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421
Complete Sequence and Characterization of Mitochondrial and Chloroplast Genome of <i>Navicula incerta</i> CACC 0356
Published 2025-01-01“…Our research presents a pioneering exploration into the complete mitochondrial and chloroplast genome sequences of <i>N. incerta</i> CACC 0356, shedding light on its phylogeny and evolutionary history. …”
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422
Identification of novel genes responsible for a pollen killer present in local natural populations of Arabidopsis thaliana.
Published 2025-01-01“…By exploiting available de novo genomic sequences, we propose a scenario for the emergence of this pollen killer in A. thaliana. …”
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423
Comparative Genome Characterization of a Petroleum-Degrading Bacillus subtilis Strain DM2
Published 2019-01-01“…The complete genome sequence of Bacillus subtilis strain DM2 isolated from petroleum-contaminated soil on the Tibetan Plateau was determined. …”
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424
A re-assessment of Taxomyces andreanae, the alleged taxol-producing fungus, using comparative genomics
Published 2022-09-01“…Consequently, the taxonomic affinities of this fungus have remained obscure. However, a full genome sequence of this strain was generated by a German research group in 2013, in an unsuccessful attempt to detect the biosynthesis genes encoding for taxol. …”
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425
Attenuation and Immunogenicity of a Live High Pathogenic PRRSV Vaccine Candidate with a 32-Amino Acid Deletion in the nsp2 Protein
Published 2014-01-01“…Furthermore, we determined the whole genome sequences of these four intermediate viruses. The results showed that after 100 passages, compared to QY1 P5, a total of 32 amino acid mutations were found. …”
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426
On the ability to extract MLVA profiles of Vibrio cholerae isolates from WGS data generated with Oxford Nanopore Technologies
Published 2025-01-01“…The MLVAType shiny application was previously designed to extract MLVA profiles of Vibrio cholerae isolates from whole-genome sequencing (WGS) data, and provide backward compatibility with traditional MLVA typing methods. …”
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427
Gut microbial 3α‐hydroxysteroid dehydrogenase promotes depression in males via degrading testosterone
Published 2025-01-01“…We found that A. koreensis administration in mice led to reduced serum testosterone levels and depression‐like behaviors, which were improved by antibiotic treatment. Using whole genome sequencing, the gene mediating testosterone degradation in A. koreensis was identified and annotated as 3α‐hydroxysteroid dehydrogenase (3α‐HSD). …”
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428
Application of Genomic Selection in Beef Cattle Disease Prevention
Published 2025-01-01“…By incorporating genomic technologies such as whole-genome sequencing, genotyping, and transcriptomics, researchers can identify specific genetic variants associated with resistance to pathogens like bovine respiratory disease and Johne’s disease. …”
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429
Egyptian Novel Goose Parvovirus in Immune Organs of Naturally Infected Ducks: Next-Generation Sequencing, Immunohistochemical Signals, and Comparative Analysis of Pathological Chan...
Published 2025-01-01“…To our knowledge, the current study is pioneering to address the immunopathological impact of NGPV among naturally infected ducks confirmed with full genome sequencing and immunohistochemical identification worldwide.…”
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430
Genomic and virulent characterization of a duck-associated Salmonella serovar Potsdam from China
Published 2025-01-01“…Our study aims to fill this gap by providing genomic features of the antimicrobial resistance and virulence potential of Salmonella isolates from dead duck embryos using whole-genome sequencing and in silico toolkits. We also sought to assess the virulent characterization of the major serovar isolates by experimental infection of chicken and duck embryos. …”
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431
Discovery of two novel Flavobacterium species with potential for complex polysaccharide degradation
Published 2025-01-01“…Through comprehensive analyses, including 16S rRNA gene sequencing, whole-genome sequencing, and detailed morphological, physiological, and chemotaxonomic characterizations, these strains have been identified as new species within the genus Flavobacterium. …”
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432
Antimicrobial Susceptibility of <i>Glaesserella parasuis</i> to Macrolides and Characterization of <i>erm</i>(T)-Carrying Mobile Elements on Chromosome
Published 2025-01-01“…Erythromycin-resistant isolates were sequenced using whole-genome sequencing. Further analysis of these sequences revealed the genetic basis of macrolide resistance in <i>G. parasuis</i>. …”
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433
A comprehensive overview of selective and novel fibroblast growth factor receptor inhibitors as a potential anticancer modality
Published 2024-03-01“…The arrival of comprehensive genome sequencing has accelerated the understanding of genetically aberrant advanced cancers and target identification for possible cancer treatment. …”
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434
Targeted dual biologic therapy for erythroderma of unknown etiology guided by high-parameter peripheral blood immunophenotyping
Published 2025-01-01“…We found that the index patient had a novel form of erythroderma characterized by increased interleukin (IL)-13- and IL-17-producing γVδ2 T cells, basophils, and activated platelets. Whole-genome sequencing of PBMCs and immunofluorescence staining of skin biopsies revealed increased expression of Th2- (IL-13, IL-4Rα) and Th17-associated markers (IL-17, IL-17Rα) and non-functional mutations associated with Th2 and Th17 signaling, demonstrating that PBMCs can reflect cutaneous disease pathology. …”
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435
Known and novel parvoviruses identified in domestic pigeons
Published 2025-01-01“…Additionally, we analyze two coding-complete genomic sequences acquired from pigeon feces in USA, one representing species Aveparvovirus columbid1 and one being a member of Chaphamaparvovirus genus in Hamaparvovirinae subfamily. …”
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436
Sources and Transmission Routes of Carbapenem-Resistant <i>Pseudomonas aeruginosa</i>: Study Design and Methodology of the SAMPAN Study
Published 2025-01-01“…Additionally, samples will be taken twice from wet hospital environments and monthly from the hospitals’ (drinking) water system, hospital and municipal wastewater treatment plants, and receiving rivers. Whole-genome sequencing will be performed to characterize CRPA isolates and determine the genetic relatedness among the isolates from different reservoirs. …”
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437
Studyof resistance of pathogenic and opportunistic fungi toantimycotics
Published 2022-03-01“…The results obtained can serve as a basis for the use of molecular methods to characterize fungi of Candida and Trichophyton genera, however, taking into account the biological features of pathogens from different groups it is reasonable to use several significant genome regions or the results of the whole genome sequencing, as well as the gene expression analysis for successful forecasting of potential resistance.…”
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438
Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities
Published 2025-02-01“…Using comprehensive genome analysis, we compared the genome of L. fermentum SD7 with 153 available genome sequences of L. fermentum strains and categorized the 154 strains into six distinct clades based on core gene single nucleotide polymorphisms. …”
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439
Pangenome mining of the Streptomyces genus redefines species’ biosynthetic potential
Published 2025-01-01“…Several thousand complete or nearly complete Streptomyces genome sequences are now available, affording the opportunity to deeply investigate the biosynthetic potential within these organisms and to advance natural product discovery initiatives. …”
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440
Genetic Diversity of Human Enterovirus in Kazakhstan, during 2022
Published 2024-01-01“…We then genotyped enteroviral subtypes associated with AM (n = 50) and HA (n = 9) using next-generation sequencing (NGS) on the viral protein 1 (VP1), followed up by whole-genome sequencing of the isolated viral species. All identified EVs were species B EV, consisting of five echoviruses (E6, E9, E11, E21, and E25) and three coxsackieviruses (CVA9, CVB3, and CVB5) serotypes within the cohort. …”
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