High-fidelity annotated triploid genome of the quarantine root-knot nematode, Meloidogyne enterolobii by Marine Poullet, Hemanth Konigopal, Corinne Rancurel, Marine Sallaberry, Celine Lopez-Roques, Ana Paula Zotta Mota, Joanna Lledo, Sebastian Kiewnick, Etienne G. J. Danchin

“…The resulting triploid genome assembly spans 285.4 Mb with 556 contigs, a GC% of 30 ± 0.042 and an N50 value of 2.11 Mb, constituting a useful platform for comparative, population and functional genomics.…”
Get full text

The complete mitochondrial genome of Gyrodactylus pseudorasborae (Platyhelminthes: Monogenea) with a phylogeny of Gyrodactylidae parasites by Xinyi Zeng, Ye Li, Yang Liu, Yaoying Chen, Yajing Liu, Mengwei Song, Tao Chen

Subjects: Get full text

Comparative genomic analysis of ten Elizabethkingia anophelis isolated from clinical patients in China by Fei Wu, Yan Wu, Miaomiao Zhang, Lijun Tian, Xue Li, Xi Luo, Yiquan Zhang, Renfei Lu

Subjects: Get full text

A re-assessment of Taxomyces andreanae, the alleged taxol-producing fungus, using comparative genomics by Tian Cheng, Miroslav Kolařík, Luis Quijada, Marc Stadler

Subjects: Get full text

RETRACTED ARTICLE: Whole-genome assembly of Akkermansia muciniphila sequenced directly from human stool by Aurélia Caputo, Grégory Dubourg, Olivier Croce, Sushim Gupta, Catherine Robert, Laurent Papazian, Jean-Marc Rolain, Didier Raoult

Get full text

Protocol for reconstructing ancestral genomes from present-day samples by applying local ancestry inference by Xiaoxi Zhang, Baonan Wang, Jia Wen, Yang Gao, Yuwen Pan, Shuhua Xu

Subjects: Get full text

Coevolution of aah: A dps-Like Gene with the Host Bacterium Revealed by Comparative Genomic Analysis by Liyan Ping, Matthias Platzer, Gaiping Wen, Nicolas Delaroque

“…A conserved genomic synteny was identified in some taxonomically related Actinobacteria, suggesting that the ancestor genes had incorporated into the genome before the divergence of Micrococcineae from other families. …”
Get full text

Complete mitochondrial genomes of Culicoides brevitarsis and Culicoides imicola biting midge vectors of Bluetongue Virus by Khandaker Asif Ahmed, Anjana Karawita, Melissa J. Klein, Luana Fiorella Mincarelli, Barbara Secondini, Giuseppe Satta, Massimo Ancora, Cipriano Foxi, Marco Di Domenico, Michela Quaglia, Maria Goffredo, Alessio Lorusso, Cesare Cammà, Leon Court, Rahul V. Rane, Tom K. Walsh, Prasad N. Paradkar, Debbie Eagles, Gunjan Pandey, Christopher M. Hardy

“…Biting midges (Culicoides spp.) are important vectors of several insect borne arboviruses but are underrepresented in terms of availability of high-resolution genomic resources. We assembled and annotated complete mitochondrial genomes for two Culicoides species, namely C. brevitarsis and C. imicola which are proven vectors for Bluetongue Virus (BTV). …”
Get full text

A genome-wide association study identifies five loci influencing facial morphology in Europeans. by Fan Liu, Fan Liu, Fedde van der Lijn, Claudia Schurmann, Gu Zhu, M Mallar Chakravarty, Pirro G Hysi, Andreas Wollstein, Oscar Lao, Marleen de Bruijne, M Arfan Ikram, Aad van der Lugt, Fernando Rivadeneira, André G Uitterlinden, Albert Hofman, Wiro J Niessen, Georg Homuth, Greig de Zubicaray, Katie L McMahon, Paul M Thompson, Amro Daboul, Ralf Puls, Katrin Hegenscheid, Liisa Bevan, Zdenka Pausova, Sarah E Medland, Grant W Montgomery, Margaret J Wright, Carol Wicking, Stefan Boehringer, Timothy D Spector, Tomáš Paus, Nicholas G Martin, Reiner Biffar, Manfred Kayser

“…We therefore conducted a genome-wide association study for facial shape phenotypes in multiple discovery and replication cohorts, considering almost ten thousand individuals of European descent from several countries. …”
Get full text

Unlocking prognostic potential: A genomic signature of caloric restriction in patients with epithelial ovarian cancer. by Ori Tal, Tamar Zahavi, Liat Anabel Sinberger, Mali Salmon-Divon

“…Based on the gene expression of these proteins, we calculated a Non-Fasting Genomic Signature score for each ovarian cancer sample sourced from the Cancer Genome Atlas (TCGA) database. …”
Get full text

Dereplication of Natural Product Antifungals via Liquid Chromatography–Tandem Mass Spectrometry and Chemical Genomics by Nathaniel J. Brittin, David J. Aceti, Doug R. Braun, Josephine M. Anderson, Spencer S. Ericksen, Scott R. Rajski, Cameron R. Currie, David R. Andes, Tim S. Bugni

Subjects: Get full text

Identification of TUBB3 as an immunotherapy target in lung cancer by genome wide in vivo CRISPR screening by Dan Zhao, Ravindra Deshpande, Kerui Wu, Abhishek Tyagi, Sambad Sharma, Shih-Ying Wu, Fei Xing, Stacey O'Neill, Jimmy Ruiz, Feng Lyu, Kounosuke Watabe

“…To identify genes underlying anti-PD-1 immunotherapy resistance using a systematic approach, we performed an in vivo genome wide CRISPR screening in lung cancer cells. …”
Get full text

Detection and Whole-Genome Characteristics of <i>Bordetella trematum</i> Isolated from Captive Snakes by Magdalena Zając, Inga Bona, Magdalena Skarżyńska, Renata Kwit, Anna Lalak, Ewelina Skrzypiec, Emilia Mikos-Wojewoda, Paulina Pasim, Dominika Wojdat, Weronika Koza, Dariusz Wasyl

“…AMR was assessed using the microbroth dilution method, while whole-genome sequencing was performed on the Illumina NextSeq platform. …”
Get full text

Biomimetic Targeted Co‐Delivery System Engineered from Genomic Insights for Precision Treatment of Osteosarcoma by Tianqi Luo, Zhijin Fan, Anyu Zeng, Anqi Wang, Yuanwei Pan, Yanyang Xu, Hongmin Chen, Weiqing Chen, Dingmeng Nie, Jiaming Lin, Anfei Huang, Ming Gong, Yufeng Huang, Yun Ding, Xiaojun Zhu, Lang Rao, Jin Wang

“…Herein, a comprehensive genomic analysis is conducted, and identified two prominent characteristics of osteosarcoma: significant cyclin‐dependent kinases 4 (CDK4) amplification and homologous recombination repair deficiency. …”
Get full text

HUMAN GENES CONTROLLING FEEDING BEHAVIOR OR BODY MASS AND THEIR FUNCTIONAL AND GENOMIC CHARACTERISTICS: A REVIEW by E. V. Ignatieva, D. A. Afonnikov, E. I. Rogaev, N. A. Kolchanov

Subjects: Get full text

Identification of Taihang-chicken-specific genetic markers using genome-wide SNPs and machine learning by Fu Wei, Zhang Ran, Ding Hong, Wang Wenjun, Liu Huage, Zang Sumin, Zhou Rongyan

“…In this study, a total of 137 individuals from Taihang and other 4 breeds were selected to construct a genome-wide SNP map. The population genetic structure analysis revealed clear differentiation among the five breeds. …”
Get full text

Nanopore sequencing reveals that DNA replication compartmentalisation dictates genome stability and instability in Trypanosoma brucei by Marija Krasiļņikova, Catarina A. Marques, Emma M. Briggs, Craig Lapsley, Graham Hamilton, Dario Beraldi, Kathryn Crouch, Richard McCulloch

“…Abstract The Trypanosoma brucei genome is structurally complex. Eleven megabase-sized chromosomes each comprise a transcribed core flanked by silent subtelomeres, housing thousands of Variant Surface Glycoprotein (VSG) genes. …”
Get full text

Genomic patterns of strain-specific genetic structure, linkage, and selection across fall armyworm populations by Ashley E. Tessnow, Rodney N. Nagoshi, Robert L. Meagher, Todd M. Gilligan, Ben M. Sadd, Yves Carrière, Holly N. Davis, Shelby J. Fleischer, Kelly Richers, John C. Palumbo, Patrick Porter, Jose Carlos Verle Rodrigues, Gregory A. Sword

Subjects: Get full text

Genomic landscape of head and neck cancer in Asia: A comprehensive meta-analysis of 1016 samples by Srikanth S. Manda, Nafisa Arfa, Neha Sharma, Aparna R. Parikh, Thomas J. Roberts, Sewanti Limaye, Venkataraman Ramachandran, Kumar Prabhash, Moni A. Kuriakose, Prashant Kumar

Get full text

Genomic selection strategies to overcome genotype by environment interactions in biosecurity-based aquaculture breeding programs by Ziyi Kang, Jie Kong, Qi Li, Juan Sui, Ping Dai, Kun Luo, Xianhong Meng, Baolong Chen, Jiawang Cao, Jian Tan, Qiang Fu, Qun Xing, Sheng Luan

“…However, these programs may exhibit a reduced genetic gain in the presence of a genotype by environment interactions (G × E) when employing biosecurity-based breeding schemes (BS), compared to non-biosecurity-based breeding schemes (NBS). Fortunately, genomic selection shows promise in improving genetic gain by taking within-family variance into account. …”
Get full text