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5781
Cuproptosis related lncRNA signature as a prognostic and therapeutic biomarker in osteosarcoma immunity
Published 2025-01-01“…The ESTIMATE algorithm, Gene Ontology and Kyoto Encyclopaedia of Genes and Genomes were applied to explore the underlying mechanisms in the immune landscape of osteosarcoma. …”
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5782
Diversity of reverse-transcriptase-containing viruses through global metagenomics
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5783
High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway
Published 2022-01-01“…Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that UPK3A was involved in the p53 signaling pathway. …”
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5784
Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer
Published 2025-02-01“…Transcriptome and clinical data of patients with GC were collected from The Cancer Genome Atlas and Gene Expression Omnibus datasets. …”
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5785
Genetic aspects of lactase deficiency in indigenous populations of Siberia
Published 2024-10-01“…Analysis of paleogenomic sequences showed that the genomes of Denisovans and Neanderthals are characterized by the above combination of alleles of the MCM6 gene. …”
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5786
Fast and Sensitive Detection of SARS-CoV-2 Nucleic Acid Using a Rapid Detection System Free of RNA Extraction
Published 2023-01-01“…The limit of detection (LoD) was determined using a negative nasopharyngeal swab matrix spiked with different concentrations of SARS-CoV-2 virus; a total of 734,337 reference sequences of viral genomes from GenBank were used for the in-silico analysis to assess the inclusivity of the assay. …”
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5787
Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer
Published 2022-01-01“…Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and gene set enrichment analysis were used for functional enrichment analysis of DEGs. …”
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5788
Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review
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5789
The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD
Published 2025-02-01“…The objective of this study was to ascertain the causal relationship between immune cells and COPD and to quantify the potential role of circulating inflammatory proteins as mediators.Methods: A two-sample Mendelian randomisation analysis was conducted involving 731 immune cells, 91 inflammatory proteins and COPD, utilising summary-level data from genome-wide association studies. The causal relationships between immune cells, inflammatory proteins and COPD were sequentially analysed by multivariate Mendelian randomisation and validated using Bayesian weighted Mendelian randomisation. …”
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5790
Molecular Assessment of Domain I of Apical Membrane Antigen I Gene in Plasmodium falciparum: Implications in Plasmodium Invasion, Taxonomy, Vaccine Development, and Drug Discovery
Published 2022-01-01“…The creation of a universal malaria vaccine based on the AMA1 antigen is challenging due to these knowledge limitations. This study used genome mining techniques to look for these particular short peptides in PfAMA1. …”
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5791
Isolation, characterization and therapeutic efficacy of lytic bacteriophage ZK22 against Salmonella Typhimurium in mice
Published 2025-01-01“…It exhibited favorable capability against 20 strains of S. Typhimurium. The genome of ZK22 consisted of a double-stranded DNA with a total length of 47,066 base pairs and a GC content of 45.71%. …”
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5792
A Drosophila melanogaster mitotype may have an adaptive meaning
Published 2019-05-01“…We compared D. melanogaster strains with different mitotypes by locomotor activity (using TriKinetics Drosophila Activity Monitor), energy expenditure (by indirect calorimetry, based on measuring oxygen consumption) and life span (under extreme conditions at 29 °C). The nuclear genomes of these strains were aligned for several generations by backcrosses. …”
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5793
Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.
Published 2024-01-01“…Differentially expressed genes (DEGs) in the dataset were screened by ClusterGVis, Weighted Gene Co-Expression Network Analysis (WGCNA) and GEO2R, and functional enrichment was performed by Gene Set Enrichment Analysis (GSEA) and Kyoto Encyclopedia of Genomes (KEGG). Then mitochondria-associated DEGs (MitoDEGs) were obtained. …”
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5794
Gene expression patterns in larval Schistosoma mansoni associated with infection of the mammalian host.
Published 2011-08-01“…<h4>Methods and principal findings</h4>All gene models from the S. mansoni genome (www.GeneDB.org) were incorporated into a high-density oligonucleotide array. …”
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5795
Identification and mechanistic insights of cell senescence-related genes in psoriasis
Published 2025-01-01“…Protein-protein interaction networks, Gene Ontology, and Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted to explore the functions and pathways of these genes. …”
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5796
Comparative transcriptomic analysis of primary endometrial cancer and bone metastatic cancer: metastasis-associated genes and abnormal cell cycle regulation
Published 2025-02-01“…The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis indicates significant changes in the Hippo signaling pathway, which regulates cell proliferation, and in the cell adhesion signaling pathway. …”
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5797
Hypermethylation at 45S rDNA promoter in cancers.
Published 2025-01-01“…Hence, clarifying hypo- or hypermethylation of rDNA will unravel its additional cellular functions, including organization of genome architecture and regulation of gene expression, in response to growth signaling, cellular stressors, and carcinogenesis. …”
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5798
Transcriptomic data reveals MYC as an upstream regulator in laying hen follicular recruitment
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5799
Determining the Potential Roles of Branched-Chain Amino Acids in the Regulation of Muscle Growth in Common Carp (Cyprinus carpio) Based on Transcriptome and MicroRNA Sequencing
Published 2023-01-01“…Kyoto Encyclopedia of Genes and Genome pathways, including the proteasome, phagosome, autophagy in animals, proteasome activator complex, and ubiquitin-dependent protein catabolic process, were enriched for these DEGs and DEMs. …”
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5800
Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis.
Published 2025-01-01“…To identify and contrast the molecular pathways underlying these morphologically and genetically distinct cell death paradigms, both mediated by follicle cells, we compared their genome-wide transcriptional, translational, and secretion profiles before and after differentiating to acquire a phagocytic capability, as well as during well-fed and nutrient-deprived conditions. …”
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