ATP1B3 may promote glioma proliferation and migration through MAPK/NF-KB signaling pathway by Qikang Yan, Quan Sun, Yan Feng, Qingyun Hu, Jinling Zhu

“…ObjectiveTo investigate the function of ATPase Na+/K+ Transporting Subunit Beta 3 (ATP1B3) in gliomas and the molecular mechanisms associated with them in order to identify a novel target and approach for glioma clinical diagnosis and treatment.MethodsThe Cancer Genome Atlas (TCGA), a public tumor database, and the Chinese Glioma Genome Atlas (CGGA) were used to evaluate the differential expression of ATP1B3 in glioma cells of various grades. …”
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Fecal microbiota is more stable during degradation and more diverse for ex situ cheetahs in Namibia compared to the USA by Morgan A. Maly, Morgan A. Maly, Morgan A. Maly, Morgan A. Maly, Reade B. Roberts, Mia M. Keady, Anne Schmidt-Küntzel, Meagan Maxwell, Laurie Marker, Matthew Breen, Carly R. Muletz-Wolz, Adrienne E. Crosier

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Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells by Ying Yin, Liquan Zhou, Shuiqiao Yuan

“…Retrotransposons comprise a significant fraction of mammalian genome with unclear functions. Increasing evidence shows that they are not just remnants of ancient retroviruses but play important roles in multiple biological processes. …”
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A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence by Georg Kuales, Matthias Weiss, Oliver Sedelmeier, Dietmar Pfeifer, Sebastian J. Arnold

“…To define the transcriptional signature of bona fide TSCs, we used inducible gain- and loss-of-function alleles of Eomes or Cdx2, and EomesGFP, to manipulate and monitor the core maintenance factors of TSCs, followed by genome-wide expression profiling. Combinatorial analysis of resulting expression profiles allowed for defining novel TSC marker genes that might functionally contribute to the maintenance of the TSC state. …”
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Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome by Karen Kelley, Shin-Ju E. Chang, Shi-Lung Lin

“…The majority of the human genome is comprised of non-coding DNA, which frequently contains redundant microsatellite-like trinucleotide repeats. …”
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Gene Structures, Classification, and Expression Models of the DREB Transcription Factor Subfamily in Populus trichocarpa by Yunlin Chen, Jingli Yang, Zhanchao Wang, Haizhen Zhang, Xuliang Mao, Chenghao Li

“…We analyzed gene structures, phylogenies, domain duplications, genome localizations, and expression profiles. The phylogenic construction suggests that the PtrDREB gene subfamily can be classified broadly into six subtypes (DREB A-1 to A-6) in Populus. …”
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Application of Next-Generation Sequencing Technology Based on Single Gene Locus in Species Identification of Mixed Meat Products by Xinmei Liu, Zhiyang Liu, Yiyu Cheng, Haijing Wu, Wei Shen, Yan Liu, Qiushi Feng, Jun Yang

“…The primers designed from mitochondrial 16S rRNA and nuclear genome gene (growth hormone receptor, GHR), respectively, were used to detect these meats. …”
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First VIM-producing representative of Pseudomonas putida group from the largest Bulgarian hospital by Atanaska Petrova, Ivan N. Ivanov, Liubomir Paunov, Angel Uchikov, Ivan Stoikov, Todor Kantardjiev, Marianna Murdjeva

“…The species group P. putida was confirmed with MALDI-TOF system and whole genome sequencing defined it as P. kurunegalensis. …”
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Response of host immune system to tick borne encephalitis virus by Iveta Stibraniova, Pavlina Bartikova, Jozef Dzubara

“…Tick-borne encephalitis virus (TBEV, Flaviviridae), a small enveloped flavivirus with an unsegmented positive-stranded RNA genome, is the most prominent member of the mammalian group of tick-borne flaviviruses. …”
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Search for Anti-EA(D) Antibodies in Subjects with an “Isolated VCA IgG” Pattern by Massimo De Paschale, Debora Cagnin, Teresa Cerulli, Maria Teresa Manco, Carlo Agrappi, Paola Mirri, Arianna Gatti, Cristina Rescaldani, Pierangelo Clerici

“…The presence of an “isolated viral capsid antigen (VCA) IgG” pattern in serum is not easy to interpret without the aid of further tests, such as specific immunoblotting or a virus genome search, that often give rise to organisational and economic problems. …”
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MFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy by Xiao-Yu Pan, Zai-Wei Zhang

“…Then, the DEGs were used for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. Finally, the protein-protein interaction (PPI) network was constructed and Cytoscape was used to find the key genes. …”
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Novel Mutations in the MKKS, BBS7, and ALMS1 Genes in Iranian Children with Clinically Suspected Bardet–Biedl Syndrome by Roghayeh Dehghan, Mahdiyeh Behnam, Mansoor Salehi, Roya Kelishadi

“…All variants were interpreted as pathogenic according to American College of Medical Genetics and Genomics (ACMG) guidelines and confirmed through Sanger sequencing. …”
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Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque by Tingfu Du, Shuaiyao Lu, Qinfang Jiang, Yun Li, Kaili Ma

“…This study is the first to explore genome-wide protein expression in hepatic tissue of diabetes macaque model using HPLC-Q-TOF/MS technology. …”
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CDC40 suppression induces CDCA5 splicing defects and anti-proliferative effects in lung cancer cells by Die Hu, Brigitte L. Thériault, Vida Talebian, Laurent Hoffer, Julie Owen, Justin Lim, Benjamin J. Blencowe, Evelyne Lima-Fernandes, Punit Saraon, Richard Marcellus, Rima Al-awar

“…Data mining of whole-genome genetic dependency screens suggest Cell Division Cycle 40 (CDC40) to be an essential protein for lung cancer cell survival. …”
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The zinc finger protein560(ZNF560) functions as a novel oncogenic gene in osteosarcoma by Xiong Dong, Guanhua Xu, Hongxiang Hong, Jinlong Zhang, Zhiming Cui, ZiLiang Yu

“…Results: By analyzing data from both the GEO and the Cancer Genome Atlas (TCGA) databases, increased expression of ZNF560 in OS tissues was verified, which was significantly associated with poorer outcomes in osteosarcoma patients both in TCGA-SARC and our own OS cohorts. …”
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Comparative Analysis of Deep Learning Algorithm for Cancer Classification using Multi-omics Feature Selection by Nur Sabrina Azmi, Azurah A Samah, Vivekaanan Sirgunan, Zuraini Ali Shah, Hairudin Abdul Majid, Chan Weng Howe, Nies Hui Wen, Nuraina Syaza Azman

“…The multi-omics data used in this study includes genomics, methylomics, transcriptomics and clinical data for a case study of lung squamous cell carcinoma. …”
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Elucidating genetic intersections: Co-differentially expressed genes in myasthenia gravis and idiopathic inflammatory myopathies and their role in comorbid pathogenesis by Wenqu Yang, Feng Liang

“…Functional enrichment analyses were performed using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. A nomogram prediction model was developed, and receiver operating characteristic (ROC) analysis was used to evaluate its diagnostic potential. …”
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Stem cell status and prognostic applications of cuproptosis-associated lncRNAs in acute myeloid leukemia by Zhuodong Chai, Zhongyue Yuan, Yifei Chen

“…Additionally, we developed a prognostic model—the cuproptosis-associated long noncoding RNA prognostic model (CRLPM)—y analyzing data from The Cancer Genome Atlas (TCGA). Patients were stratified into high- and low-risk groups based on CRLPM, revealing significant survival differences. …”
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Metagenomic Detection of Multiple Viruses in Monk Parakeet (Myiopsitta monachus) in Australia by Babu Kanti Nath, Suman Das Gupta, Saranika talukder, Nasrin Sultana Tonu, Shane R. Raidal, Jade K. Forwood, Subir Sarker

“…Virus enrichment and nucleic acid extraction were performed on the faecal samples, followed by high‐throughput sequencing at the Australian Genome Research Facility (AGRF). Results Utilising an established pipeline for high‐throughput sequencing data analysis, this study revealed the presence of three viruses of the families Circoviridae, Parvoviridae and Adenoviridae. …”
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Introgressions of Vitis rotundifolia Michx. to obtain grapevine genotypes with complex resistance to biotic and abiotic stresses by V. A. Volynkin, V. V. Likhovskoi, I. A. Vasylyk, N. A. Rybachenko, E. A. Lushchay, S. M. Gorislavets, V. A. Volodin, V. I. Risovannaya, E. K. Potokina

“…As a result, almost all recombinant genotypes that received a resistant allele from the paternal genome are highly resistant to powdery mildew.…”
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