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4941
Nuclear mRNA export
Published 2024-09-01“…While these mechanisms are generally conserved across eukaryotes, significant differences exist between yeast and higher eukaryotic cells, particularly due to the more genome complexity of the latter. …”
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4942
NHÂN DÒNG VÀ NGHIÊN CỨU MỨC ĐỘ METHYL HÓA VÙNG ICR (Imprinting control region) TRÊN LOCUS Igf2/H19 Ở CHUỘT (Mus musculus)
Published 2012-11-01“…Epigenetic (ngoại di truyền) là hiện tượng trong quá trình in dấu hệ gen (genome imprinting) mà chỉ một allele bố mẹ được biểu hiện tùy thuộc vào nguồn gốc allele đó. …”
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4943
The homeobox family gene signature predicts the prognosis of osteosarcoma and correlates with immune invasion
Published 2025-01-01“…Data from osteosarcoma patients in The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) cohorts were collected. …”
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4944
Sequence Variants of ADIPOQ and Association with Type 2 Diabetes Mellitus in Taiwan Chinese Han Population
Published 2014-01-01“…Diabetes is a serious global health problem. Large-scale genome-wide association studies identified loci for type 2 diabetes mellitus (T2DM), including adiponectin (ADIPOQ) gene and transcription factor 7-like 2 (TCF7L2), but few studies clarified the effect of genetic polymorphisms of ADIPOQ and TCF7L2 on risk of T2DM. …”
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4945
A SH3b domain-containing peptidoglycan recognition protein from Magallana gigas with broad recognition spectrum
Published 2025-06-01“…In the present study, nine MgPGRP genes were identified in the updated genome of Magallana gigas, and the cDNA of MgPGRP5 which was consisted of a SH3b and a PGRP domain was cloned. …”
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4946
Leptospira and Inflammation
Published 2012-01-01“…The recent sequencing of the Leptospira genome has increased our knowledge about this pathogen. …”
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4947
D-2-hydroxyglutarate impairs DNA repair through epigenetic reprogramming
Published 2025-02-01“…Oncometabolites jeopardize genome stability and DNA repair by affecting high-order chromatin structure.…”
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4948
MOLECULAR IDENTIFICATION OF ROOT-KNOT NEMATODES MELOIDOGYNE SPP. ISOLATED FROM CUCUMBER FARMS IN DIFFERENT IRAQI REGIONS
Published 2024-12-01“…PCR was used to amplify the part of the Meloidogyne spp. genome between the COI and 16S mtDNA genes. Afterward, M. incognita, M. hapla, M. javanica, M. enterolobii, and M. arenaria were genotyped using Sequence Characterized Amplified Region (SCAR-PCR), with decreasing prevalence rates, respectively. …”
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4949
Gene Expression Changes in Venous Segment of Overflow Arteriovenous Fistula
Published 2013-01-01“…Total RNA was extracted from the venous tissue samples, and gene expression between the 2 groups was compared using Whole Human Genome DNA microarray 44 K. Microarray data were analyzed by GeneSpring GX software and Ingenuity Pathway Analysis. …”
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4950
First detection of recombinant variant of African swine fever virus in the Russian Federation (brief communication)
Published 2024-09-01“…As part of extensive molecular and genetic research into African swine fever virus isolates circulating in Russia, a recombinant variant with a mosaic genome structure has been identified. The one that caused an outbreak on a pig farm in the Primorsky Krai, in 2023. …”
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4951
BRD8 Guards the Pluripotent State by Sensing and Maintaining Histone Acetylation
Published 2025-02-01“…This data supports a model for BRD8 reading histone acetylation to accurately localize the genome‐wide binding of the histone acetyltransferase KAT5. …”
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4952
Migration of primordial germ cells and their relationship of PGCs with sex development in transgenic germline-specific fluorescent freshwater angelfish (Pterophyllum scalare)
Published 2025-01-01“…In this study, we developed a novel transgenic line, Tg(ddx4:TcCFP13-nanos3), based on the Nile tilapia genome, to label PGCs with clear fluorescent signals in the freshwater angelfish (Pterophyllum scalare). …”
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4953
HSV-1 miR-H6 Inhibits HSV-1 Replication and IL-6 Expression in Human Corneal Epithelial Cells In Vitro
Published 2012-01-01“…It has been previously demonstrated that miR-H6 encoded from HSV-1 genome targets ICP4 to help maintain latency. In this study, synthesized miR-H6 mimics were transfected into HSV-1-infected human cornea epithelial (HCE) cells. …”
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4954
Genetic analyses identify circulating genes related to brain structures associated with Parkinson’s disease
Published 2025-01-01“…However, their relationships remain insufficiently studied. Using genome-wide association summary statistics, we found in the general population a genetic negative correlation between white matter tract mean diffusivity and PD (-0.17 < Rg < -0.11, p < 0.05), and a positive correlation with intracellular volume fraction (0.12 < Rg < 0.2, p < 0.05). …”
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4955
Clinical Relevance of HLA Gene Variants in HBV Infection
Published 2016-01-01“…The human leukocyte antigen (HLA) system, the major histocompatibility complex (MHC) in humans, is one of the most important host factors that are correlated with the clinical course of HBV infection. Genome-wide association studies (GWASs) have shown that single nucleotide polymorphisms (SNPs) near certain HLA gene loci are strongly associated with not only persistent HBV infection but also spontaneous HBV clearance and seroconversion, disease progression, and the development of liver cirrhosis and HBV-related hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB). …”
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4956
Amelioration of dextran sodium sulphate-induced colitis in mice by treatment with Lactobacillus rhamnosus and Lactobacillus reuteri: intraspecific and interspecific patterns
Published 2024-09-01“…In this study, four strains each of Rh and Re were isolated from fecal samples and their draft genomes were sequenced. The anti-colitis activities of both strains involved various aspects of intestinal immune, physical, chemical, and biological barrier function. …”
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4957
Some anatomical, morphological and physiological features of the flag leaf in introgressive bread wheat lines with <i>Aegilops columnaris</i> Zhuk. genetic material
Published 2024-07-01“…A negative effect of substitutions of chromosomes 2A, 5B, 6A and 6D for chromosomes of the U and X genomes on the size of the flag leaf area was disclosed. …”
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4958
First Molecular and Phylogenetic Characterization of Equine Herpesvirus-1 (EHV-1) and Equine Herpesvirus-4 (EHV-4) in Morocco
Published 2025-01-01“…A subset of EHV-positive samples underwent virus isolation followed by whole-genome sequencing. PCR assays revealed that 42 samples (27%) tested positive for EHV-4, while only 3 samples (1.94%) were positive for EHV-1. …”
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4959
Raise of short-stemmed vaviloid branched spike lines and their cytogenetics
Published 2015-07-01“…The chromosome composition of one of the lines (378/3SD) was characterized by fluorescence in situ hybridization (FISH) and genome in situ hybridization (GISH), and it was identified as a substitution line. …”
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4960
FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy
Published 2025-02-01“…Here we report that O-GlcNAcylation level is positively correlated with EC histologic grade in a Chinese cohort containing 219 tumors, validated in The Cancer Genome Atlas dataset. Increasing O-GlcNAcylation in patient-derived endometrial epithelial organoids promotes proliferation and stem-like cell properties, whereas decreasing O-GlcNAcylation limits the growth of endometrial cancer organoids. …”
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