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4241
An approximate likelihood method reveals ancient gene flow between human, chimpanzee and gorilla
Published 2024-01-01“…Distinguishing between the two processes is a key objective of current evolutionary genomics. This is most often pursued via the so-called ABBA-BABA type of method, which relies on a prediction of symmetry of gene tree discordance made by the incomplete lineage sorting hypothesis. …”
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4242
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4243
Evaluation of Positron Emission Tomographic Tracers for Imaging of Papillomavirus-Induced Tumors in Rabbits
Published 2014-01-01“…New Zealand White rabbits were infected with cottontail rabbit papillomavirus genomes and were imaged for up to 10 months with a simultaneous PET/MR system during the course of infection. …”
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4244
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4245
The Role of the Key Differentially Mutated Gene FGFR3 in the Immune Microenvironment of Bladder Cancer
Published 2022-01-01“…In this work, we downloaded the RNA-seq expression profiles and somatic mutation data of 433 bladder cancer cases from The Cancer Genome Atlas (TCGA) and then employed a comprehensive bioinformatics approach to evaluate them. …”
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4246
The Systematic Analysis of Exercise Mechanism in Human Diseases
Published 2022-01-01“…To study and analyze the samples in the GSE18966 gene expression profile, we first performed an analysis on the differential expressed genes (DEGs) through GEO2R, and then the DEGs enrichment in Gene Ontology functions and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways through the Database for Annotation, Visualization and Integrated Discovery database was conducted. …”
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4247
Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers
Published 2025-02-01“…Enrichment analyses using gene ontology, Kyoto Encyclopedia of Genes and Genomes, and gene set enrichment were performed. Protein-protein interaction networks were constructed to identify key genes, and regulatory networks involving transcription factors, miRNAs, and RNA-binding proteins were established. …”
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4248
Exploration on Molecular Mechanism of Reversal Effect of Compound Danshen Tablets on Hepatic Fibrosis Based on Network Pharmacology
Published 2022-01-01“…The DAVID enrichment database (the database for annotation, visualization, and integrated discovery) was adopted for GO (Gene Ontology) enrichment and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway enrichment of vital nodes. Results. …”
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4249
Why Rights are Wrong in ASEAN and Beyond: A Critique of the Foundations of Universal Human Rights
Published 2020-05-01“…Part Two then examines whether the original axiomatic listing of human rights or an iteration of human rights founded upon the human genome or a Kantian underpinning can legitimise human rights and, if not, whether reference to the human soul made in the image of God with its natural law may substantiate the human rights project, perhaps, articulated as congruent with the purpose and design courts now recognise in the natural laws found in every ecosystem of nature. …”
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4250
A hypothesis about interrelations of epigenetic factors and transposable elements in memory formation
Published 2024-09-01“…The data obtained suggest that transposons, which are genome sensors highly sensitive to various environmental and internal influences, form memory at the nuclear coding level. …”
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4251
Mutations of the Electron Transport Chain Affect Lifespan and ROS Levels in <i>C. elegans</i>
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4252
Identification of Molecular Subtypes and Prognostic Features of Breast Cancer Based on TGF-β Signaling-related Genes
Published 2025-02-01“…However, the specific role of TGF-β in prognostic assessment and treatment strategies for breast cancer (BC) remains unclear. Methods: The Cancer Genome Atlas (TCGA) database was utilized to develop a predictive model incorporating five TGF-β signaling-related genes (TSRGs). …”
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4253
Seasonal Dynamics of the Bacterial Community in Lake Urmia, a Hypersaline Ecosystem
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4254
Data from a multi-year targeted proteomics study of a longitudinal birth cohort of type 1 diabetes
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4255
Prenatal Diagnosis of Rare Familial Unbalanced Translocation of Chromosomes 7 and 12
Published 2015-01-01“…Ultrasonography findings included fetal microcephaly and alobar holoprosencephaly, dysmorphic face (flat occiput, absent nasal bone, microphthalmia, hypotelorism, and single nostril), and hyperechogenic bowel. Genome-wide array analysis and cytogenetic results from the amniotic fluid showed unbalanced translocation in chromosomes 7 and 12 with deletion of an approximately 16.5 Mb and a duplication of 6.1 Mb, respectively, Arr 7q34q36.3(142,668,576-159,161,648)x1,12q24.32q24.33(127,708,720-133,777,560)x3, karyotype (der (7) t(7;12) (q34;q24)pat). …”
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4256
Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer
Published 2023-01-01“…We tried to identify the key factors of the p53 signaling pathway involved in gastric cancer (GC) occurrence and development based on the genotype-tissue expression (GTEx) and the Cancer Genome Atlas (TCGA) screening. We downloaded gene expression data and clinical data of GC included in the GTEx and TCGA databases, followed by differential analysis. …”
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4257
Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis.
Published 2025-01-01“…We explored the roles of these DEGs in cellular senescence through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. We then pinpointed three key genes (DHX9, CYR61, and ITGB) using random forest and LASSO Cox regression machine learning techniques. …”
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4258
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4259
lncRNA ZFAS1 Promotes HMGCR mRNA Stabilization via Binding U2AF2 to Modulate Pancreatic Carcinoma Lipometabolism
Published 2022-01-01“…ZFAS1 expression in PC and normal counterparts retrieved from the Genotype-Tissue Expression (GTEx) project and The Cancer Genome Atlas (TCGA) database was analysed by GEPIA2. …”
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4260