Variability of mitochondrial DNA D-loop sequences in Zabaikalskaya horse breed by L. A. Khrabrova, N. V. Blohina, B. Z. Bazaron, T. N. Khamiruev

“…Genetic analysis of the mitochondrial genome of the Zabaikalskaya horse revealed a high level of diversity of haplotypes and haplogroups, which are typical for the horse populations of Eurasia.…”
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Establishment of Novel Limbus-Derived, Highly Proliferative ABCG2+/ABCB5+ Limbal Epithelial Stem Cell Cultures by Eung Kweon Kim, Ga-Hyun Lee, Boram Lee, Yong-Sun Maeng

“…In addition, cultured LESCs expressed high levels of the stem cell markers Sox2, Oct4, c-Myc, and Klf4, had high telomerase activity, and had stable, normal genomes. These results suggest that our novel cultivation protocol affects the phenotype and differentiation capacity of LESCs. …”
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Causal Relationship Between Psoriasis and Bullous Pemphigoid: A Mendelian Randomization Analysis by Xiaoxue Wang, Zexin Zhu

“…Objectives: In order to explore the causal relationship between psoriasis and BP, we performed a bidirectional two-sample Mendelian randomization (MR) study. Methods: Genome-wide association study (GWAS) data related to psoriasis and BP were collected. …”
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Cyclin-dependent protein kinases and cell cycle regulation in biology and disease by Ilenia Pellarin, Alessandra Dall’Acqua, Andrea Favero, Ilenia Segatto, Valentina Rossi, Nicole Crestan, Javad Karimbayli, Barbara Belletti, Gustavo Baldassarre

“…In reality, the human genome contains 20 different CDKs, which can be divided in at least three different sub-family with different functions, mechanisms of regulation, expression patterns and subcellular localization. …”
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Latest Approved Therapies for Metastatic Melanoma: What Comes Next? by Farid Menaa

“…Eventually, multidisciplinary approaches are still requested (e.g., genomics for personalized medicine, nanomedicine to overcome low free-drug bioavailability and targeting, systematic search of “melanoma stem cells” to enhance the prognosis and develop more valuable theranostics). …”
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<i>Salmonella</i> bacteria in farm animal feeds. Review by N. B. Shadrova, O. V. Pruntova, G. S. Skitovich, О. А. Akulich

“…A research into antimicrobial resistance of Salmonella isolates demonstrated resistance to such medicinalproducts as ceftriaxone, carbopenem and imipenem; and full genome sequencing showed at least one antibiotic resistance gene in 40% of Salmonella isolates detected at pig feed production plants.…”
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Rule-Based Knowledge Acquisition Method for Promoter Prediction in Human and Drosophila Species by Wen-Lin Huang, Chun-Wei Tung, Chyn Liaw, Hui-Ling Huang, Shinn-Ying Ho

“…The rapid and reliable identification of promoter regions is important when the number of genomes to be sequenced is increasing very speedily. …”
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Truncated SPAG9 as a novel candidate gene for a new syndrome: Coarse facial features, albinism, cataract and developmental delay (CACD syndrome) by Majid Alfadhel, Bashayr S. Alhubayshi, Muhammad Umair, Ahmed Alfaidi, Deemah Alwadaani, Essra Aloyouni, Safdar Abbas, Abdulkareem Al Abdulrahman, Mohammed Aldrees, Abeer Al Tuwaijri, Ruaa S. Alharithy, Abdulaziz Alajlan, Abdulrahman Alswaid, Saad Almohrij, Sultan Al-Khenaizan

“…We identified two families (A and B) having multisystem features like coarse facial features, albinism, cataracts, skeletal abnormalities, and developmental delay. Whole genome sequencing (WGS) in families A and B revealed a homozygous frameshift variant (c.903del; p.Phe301Leufs*2) in the SPAG9 gene. …”
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Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response by Guo Liu, Feng Liu

“…Furthermore, studies in various animal models show that Bach2 knockout animals spontaneously develop Th2 inflammation in the airway and gastrointestinal tract. Genome-wide association studies have identified various susceptibility loci of Bach2 which are linked with Th2 inflammatory diseases such as asthma and inflammatory bowel disease. …”
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Bioinformatics Analysis, Prokaryotic Expression and Biological Activity of Lysin from Vibrio parahaemolyticus Phage vB_VpP_1 by ZHANG Defu, YANG Wenjing, LIU Ke, LIU Qingqing, BAI Wutong, LI Fan, LÜ Xinran, BAI Xue, TAN Xiqian, LI Xuepeng, LI Jianrong

“…To study the in vitro cleavage effect of a recombinant lysin from bacteriophage vB_VpP_1 on Vibrio parahaemolyticus, the gp32 gene fragment of vB_VpP_1 was identified as a lysin gene according to the results of whole-genome sequencing (WGS) and functional analysis. The amino acid sequence and structure of gp32 were analyzed by various tools such as Expasy. …”
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Synthesis, Structure, and Anticancerous Properties of Silver Complexes by Shraddha Shukla, A. P. Mishra

“…The completion of the human genome sequence and its subsequent improvements in the sequence data are important steps to fully comprehend cancer cell biology. …”
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Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. by William M Brandler, Andrew P Morris, David M Evans, Thomas S Scerri, John P Kemp, Nicholas J Timpson, Beate St Pourcain, George Davey Smith, Susan M Ring, John Stein, Anthony P Monaco, Joel B Talcott, Simon E Fisher, Caleb Webber, Silvia Paracchini

“…The molecular basis of these asymmetries is unknown. We report a genome-wide association study meta-analysis for a quantitative measure of relative hand skill in individuals with dyslexia [reading disability (RD)] (n = 728). …”
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Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response by Sophie C. van der Horst, Leonie Kollenstart, Amandine Batté, Sander Keizer, Kees Vreeken, Praveen Pandey, Andrei Chabes, Haico van Attikum

“…Here, we develop Replication-IDentifier (Repli-ID), which allows for genome-wide identification of regulators of DNA replication in Saccharomyces cerevisiae. …”
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A Nonoscillatory Second-Order Time-Stepping Procedure for Reaction-Diffusion Equations by Philku Lee, George V. Popescu, Seongjai Kim

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Potential for Isolation of Immortalized Hepatocyte Cell Lines by Liver-Directed In Vivo Gene Delivery of Transposons in Mice by Masahiro Sato, Issei Saitoh, Emi Inada, Shingo Nakamura, Satoshi Watanabe

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Structure‐based computational design of antibody mimetics: challenges and perspectives by Elton J. F. Chaves, Danilo F. Coêlho, Carlos H. B. Cruz, Emerson G. Moreira, Júlio C. M. Simões, Manassés J. Nascimento‐Filho, Roberto D. Lins

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Innovative approaches in colorectal cancer screening: advances in detection methods and the role of artificial intelligence by Changwei Duan, Jianqiu Sheng, Xianzong Ma

“…This review aims to provide a comprehensive perspective on new strategies for CRC screening, emphasizing the potential of noninvasive detection technologies and the prospects of AI and genomics in clinical applications. Despite several challenges, this review advocates for future large-scale prospective studies to validate the effectiveness and cost-effectiveness of these new screening methods while promoting the implementation of screening protocols tailored to individual characteristics.…”
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Human Gut Microbes Associated with Systolic Blood Pressure by Tulsi Kumari Joishy, Aashish Jha, Mai Oudah, Santanu Das, Atanu Adak, Dibyayan Deb, Mojibur Rohman Khan

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Melittin, a Potential Natural Toxin of Crude Bee Venom: Probable Future Arsenal in the Treatment of Diabetes Mellitus by Md. Sakib Hossen, Siew Hua Gan, Md. Ibrahim Khalil

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Applications of Healthcare Robots in Combating the COVID-19 Pandemic by Shruti Raje, Nikunj Reddy, Houssem Jerbi, Princy Randhawa, Georgios Tsaramirsis, Nikhil Vivek Shrivas, Athanasia Pavlopoulou, Miloš Stojmenović, Dimitris Piromalis

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