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4001
Learning with semantic ambiguity for unbiased scene graph generation
Published 2025-01-01“…Our approach is evaluated on widely-used datasets, including Visual Genome and Generalized Question Answering, both with over 100,000 images, providing rich visual contexts for scene graph model evaluation. …”
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4002
Comparison of Procleix Ultrio Elite and Procleix Ultrio NAT Assays for Screening of Transfusion Transmitted Infections among Blood Donors in India
Published 2016-01-01“…NAT combines the advantages of direct and highly sequence-specific detection of viral genomes. We analysed the performance of newer Procleix Ultrio Elite (PUE) and Procleix Ultrio assay (PUA) for the screening of the viral markers in our donor population. …”
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4003
Identification and expression analysis of the ZF-HD gene family in castor
Published 2024-12-01“…[Methods] Based on the whole genome data of castor, ZF-HD genes were identified, and bioinformatics and expression analysis under abiotic stress were carried out. …”
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4004
Inheritance patterns of male asexuality in hybrid males of a water frog Pelophylax esculentus
Published 2024-09-01“…Also, most male tadpole progeny in two successive backcrossed generations simultaneously eliminated L and R parental genomes, while some progeny produced only one type of sperm. …”
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4005
A Micro-RNA Connection in BRafV600E-Mediated Premature Senescence of Human Melanocytes
Published 2012-01-01“…Recent high-throughput-sequencing of the cancer genome has identified oncogenic mutations in BRaf genetic locus as one of the critical events in melanomagenesis. …”
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4006
Prospects for marker-associated selection in tomato <i>Solanum lycopersicum</i> L.
Published 2019-08-01“…A separate chapter is devoted to the use of various types of DNA markers for constructing detailed genetic maps of the specified object, which, along with full-genome sequencing data, can be used to screen for genes responsible for breeding traits. …”
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4007
Single-cell transcriptomes reveal cell-type-specific and sample-specific gene function in human cancer
Published 2025-02-01“…We found that 500 or more cells should be considered in the prediction with scRNA-seq, and that scRNA-seq datasets generated from 10x Genomics platform had a better performance than those from Smart-seq2. …”
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4008
Recent Advances in the Pathogenesis of Syndromic Autisms
Published 2009-01-01“…Identifying cryptic chromosomal abnormalities by whole genome microarray analysis can increase the understanding of the neurobiological pathways to autism.…”
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4009
GENES DETERMINING THE SYNTHESIS OF LAVONOID AND MELANIN PIGMENTS IN BARLEY
Published 2018-05-01“…Since the 1970s, structural genes that encode the enzymes of lavonoid metabolism, as well as regulatory genes that determine the tissue-speciic accumulation of these pigments in grain tissues, as well as in vegetative organs have been identiied and localized in the barley genome. The Ant1 and Ant2 genes, determining the accumulation of anthocyanins in grain pericarp, the Ant28 gene controlling the biosynthesis of proanthocyanidins (condensed tannins) in seed coat, as well as the HvMpc2, HvMyc2 and HvWD40 genes responsible for the accumulation of anthocyanins in the aleurone layer of barley grain have been determined. …”
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4010
Genotyping of HCV RNA Reveals That 3a Is the Most Prevalent Genotype in Mardan, Pakistan
Published 2014-01-01“…RNA was extracted from serum and reverse-transcribed to cDNA and the core region of HCV genome was targeted and amplified by multiplex PCR. …”
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4011
Evaluation and Prediction of the HIV-1 Central Polypurine Tract Influence on Foamy Viral Vectors to Transduce Dividing and Growth-Arrested Cells
Published 2014-01-01“…In this process, the HIV-1 central polypurine tract (cPPT) serves as a primer for plus-strand synthesis to produce a “flap” element and is believed to be crucial for the subsequent double-stranded cDNA formation of all retroviral RNA genomes. In this study, the effects of the lentiviral cPPT element on the FV transduction potential in dividing and growth-arrested (G1/S phase) adenocarcinomic human alveolar basal epithelial (A549) cells are investigated by experimental and theoretical methods. …”
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4012
Loss of Lkb1 cooperates with BrafV600E and ultraviolet radiation, increasing melanoma multiplicity and neural‐like dedifferentiation
Published 2025-02-01“…Analysis of human melanoma tumors [data from The Cancer Genome Atlas (TCGA)] revealed that 50% or more of the samples expressed no or low amounts of serine/threonine protein kinase STK11 (also known as LKB1) protein. …”
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4013
Integration of single-cell and bulk RNA-sequencing data to construct and validate a signature based on NK cell marker genes to predict immunotherapy response and prognosis in color...
Published 2025-02-01“…We integrated scRNA-seq data from four Gene Expression Omnibus (GEO) samples and performed Weighted gene correlation network analysis (WGCNA) based on 587 the Cancer Genome Atlas (TCGA) colorectal cancer samples to uncover NK cell-related genes. …”
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4014
Diet-derived urolithin A is produced by a dehydroxylase encoded by human gut Enterocloster species
Published 2025-01-01“…Here, we use a combination of untargeted bacterial transcriptomics, proteomics, and comparative genomics to uncover an inducible uroC dehydroxylase (ucd) operon in Enterocloster species. …”
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4015
Integrated Bioinformatics-Based Identification of Potential Diagnostic Biomarkers Associated with Diabetic Foot Ulcer Development
Published 2021-01-01“…These DEGs were then arranged into a protein-protein interaction (PPI) network, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and Gene Ontology (GO) term enrichment analyses were performed to explore the functional roles of these genes. …”
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4016
Therapies for Mitochondrial Disorders
Published 2022-12-01“…Mitochondria contain their own genome, mitochondrial DNA (mtDNA), which is maternally inherited from the oocyte. …”
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4017
Systematic and Cell Type-Specific Telomere Length Changes in Subsets of Lymphocytes
Published 2016-01-01“…Telomeres, the protective DNA-protein complexes at the ends of linear chromosomes, are important for genome stability. Leukocyte or peripheral blood mononuclear cell (PBMC) telomere length is a potential biomarker for human aging that integrates genetic, environmental, and lifestyle factors and is associated with mortality and risks for major diseases. …”
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4018
The Pathogenesis of Nonalcoholic Fatty Liver Disease: Interplay between Diet, Gut Microbiota, and Genetic Background
Published 2016-01-01“…Moreover, several genetic variants have been identified through genome-wide association studies, particularly rs738409 (Ile748Met) in PNPLA3 and rs58542926 (Glu167Lys) in TM6SF2, which are critical risk alleles of the disease. …”
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4019
Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer
Published 2025-01-01“…We utilized these two algorithms to analyze the immune components of 433 bladder cancer cases from The Cancer Genome Atlas database, aiming to compensate for the current lack of large-sample single-cell information. …”
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4020
Antioxidant and cytotoxic potentials of Streptomyces gilvigriseus MUSC 26T isolated from mangrove soil in Malaysia
Published 2018-07-01“…By the same token, the availability of its genome sequence allows further investigation into the biosynthetic gene clusters responsible for the production of these compounds which could essentially accelerate its development as chemopreventive drug(s).…”
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