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3921
Colitis in spondyloarthritis
Published 2020-01-01“…Apart from the strong Class I human leukocyte antigen B27 link for both diseases, several new shared genetic risk loci are identified from genome-wide association studies. Demonstrable mucosal inflammation of gut is present in most of the patients with SpA, even in the absence of clinically overt IBD. …”
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3922
Science et développement : l’action de François Gros au COPED
Published 2023-12-01Get full text
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3923
The war inside your mind: unprotected brain battlefields and neuro-vulnerability
Published 2024-02-01“… The 21st century featured explosive discoveries, inventions, and finely crafted technologies where the vaguely dangerous and ambiguous mix of genomics, neuroscience, nanotech, robotics, cyber, and other advanced scientific ventures leads to unknown and possibly unpleasant outcomes pose an acute dilemma. …”
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3924
Monkeypox and other orthopoxvirus zoonoses
Published 2022-09-01“…Scientists are alarmed by these facts as the camelpox virus genomeis 99% homologous to the genome of the small poxvirus. This requires strengthening the epizootological and epidemiological monitoring of orthopoxvirus zoonotic pathogens.…”
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3925
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3926
Evaluation of Transforming Growth Factor Beta-1 Gene 869T/C Polymorphism with Hypertension: A Meta-Analysis
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3927
Metabolic Analysis of the Mode of Action and Mode of Resistance for Novobiocin in Staphylococcus aureus
Published 2025-01-01“…Further metabolomic analysis revealed the function of the major mutation (in gyrB) in relation to the potential mechanism through which S. aureus responds to novobiocin. Through whole genome sequencing, three mutations of S. aureus in gyrB, potB, and fpgS were identified. …”
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3928
Correlation between Ferroptosis-Related Gene Signature and Immune Landscape, Prognosis in Breast Cancer
Published 2022-01-01“…FRG expression profiles and clinical data were downloaded from The Cancer Genome Atlas (TCGA) database and Gene Expression Omnibus (GEO). …”
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3929
NOS2 as a prognostic biomarker for early-onset colorectal cancer based on public data and clinical validation analysis
Published 2025-02-01“…EOCRC from The Cancer Genome Atlas Program (TCGA) database and Gene Expression Mapping (GEO) database were used to screen biomarkers for prognosis and treatment guidance. …”
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3930
Mitogenomic Phylogenetic Analyses Reveal New Insights into the Taxonomy and Evolution of Parnassiinae Swallowtail Butterflies (Lepidoptera: Papilionidae)
Published 2024-12-01“…Mitochondrial genomes provide powerful insights into insect phylogeny and molecular evolution, aiding in the clarification of complex taxonomic relationships. …”
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3931
Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets
Published 2017-01-01“…Our research group recently described genome-wide characterization of motor cortex samples from sporadic ALS (SALS) patients, revealing the existence of molecular and functional heterogeneity in SALS. …”
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3932
A CACTA-like transposon in the Anthocyanidin synthase 1 (Ans-1) gene is responsible for apricot fruit colour in the raspberry (Rubus idaeus) cultivar 'Varnes'.
Published 2025-01-01“…By performing RNASeq, we revealed differential expression patterns in the apricot-fruited 'Varnes' for genes in the anthocyanin biosynthesis pathway and following whole genome sequencing using long-read Oxford Nanopore Technologies sequencing, we identified a CACTA-like transposable element (TE) in the second exon of the Anthocyanidin synthase (Ans) gene that caused a truncated predicted ANS protein. …”
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3933
RECQ4-MUS81 interaction contributes to telomere maintenance with implications to Rothmund-Thomson syndrome
Published 2025-02-01“…This underscores the importance of RECQ4-MUS81 in safeguarding genome integrity and suggests potential implications for human disease. …”
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3934
Application of Metabolomics in Thyroid Cancer Research
Published 2015-01-01“…However, in some cases, cytological and histological patterns are inconclusive; hence, classification based on histopathology could be supported by molecular biomarkers, including markers identified with the use of high-throughput “omics” techniques. Beside genomics, transcriptomics, and proteomics, metabolomic approach emerges as the most downstream attitude reflecting phenotypic changes and alterations in pathophysiological states of biological systems. …”
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3935
Rapid Identification and Systematic Mechanism of Flavonoids from Potentilla freyniana Bornm. Based on UHPLC-Q-Exactive Orbitrap Mass Spectrometry and Network Pharmacology
Published 2021-01-01“…Finally, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were carried out via DAVID. …”
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3936
Determination of FMDV 146S particle concentration by spectrometric method during viral RNA quantification
Published 2021-01-01“…Tests of the positive control demonstrated 99.0–99.6% compatibility of actual and expected results. FMDV genome and 146S particles were not detected in the negative control, and that was in line with expectations.…”
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3937
Nuclear mRNA export
Published 2024-09-01“…While these mechanisms are generally conserved across eukaryotes, significant differences exist between yeast and higher eukaryotic cells, particularly due to the more genome complexity of the latter. …”
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3938
NHÂN DÒNG VÀ NGHIÊN CỨU MỨC ĐỘ METHYL HÓA VÙNG ICR (Imprinting control region) TRÊN LOCUS Igf2/H19 Ở CHUỘT (Mus musculus)
Published 2012-11-01“…Epigenetic (ngoại di truyền) là hiện tượng trong quá trình in dấu hệ gen (genome imprinting) mà chỉ một allele bố mẹ được biểu hiện tùy thuộc vào nguồn gốc allele đó. …”
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3939
Sequence Variants of ADIPOQ and Association with Type 2 Diabetes Mellitus in Taiwan Chinese Han Population
Published 2014-01-01“…Diabetes is a serious global health problem. Large-scale genome-wide association studies identified loci for type 2 diabetes mellitus (T2DM), including adiponectin (ADIPOQ) gene and transcription factor 7-like 2 (TCF7L2), but few studies clarified the effect of genetic polymorphisms of ADIPOQ and TCF7L2 on risk of T2DM. …”
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3940
A SH3b domain-containing peptidoglycan recognition protein from Magallana gigas with broad recognition spectrum
Published 2025-06-01“…In the present study, nine MgPGRP genes were identified in the updated genome of Magallana gigas, and the cDNA of MgPGRP5 which was consisted of a SH3b and a PGRP domain was cloned. …”
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