Modern Genetic Education: How Does It Meet Students’ Requests? by T. A. Sedykh, L. A. Amirova, L. A. Gaysina, G. F. Galikeeva, A. I. Fazlutdinova, N. V. Sukhanova

“…It was found that despite the satisfaction of the majority of the surveyed students with the quality of genetic education, there are problems in understanding modern sections of genetics, such as molecular genetics, toxicological genetics, genomics. The students are not sufficiently involved in scientific research, most of them prefer the traditional forms of teaching and learning, only few of them are aware of modern online resources and MOOCs. …”
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Ultrasound Radiogenomics-based Prediction Models for Gene Mutation Status in Breast Cancer by Zhai Yue, Tan Dianhuan, Lin Xiaona, Lv Heng, Chen Yan, Li Yongbin, Luo Haiyu, Dan Qing, Zhao Chenyang, Xiang Hongjin, Zheng Tingting, Sun Desheng

“…Ultrasound radiogenomics, an emerging field at the intersection of radiology and genomics, employs high-throughput methods to convert radiological images into high-dimensional data, which are then processed to extract and analyze radiomic features. …”
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Role of New Biomarkers: Functional and Structural Damage by Evdoxia Tsigou, Vasiliki Psallida, Christos Demponeras, Eleni Boutzouka, George Baltopoulos

“…Innovative technologies such as genomics and proteomics have contributed to the discovery of new biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys C), kidney injury molecule-1 (KIM-1), interleukin-18 (IL-18), and liver-type fatty acid binding protein (L-FABP). …”
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Targeting Toll-Like Receptors for Treatment of SLE by Christopher G. Horton, Zi-jian Pan, A. Darise Farris

“…Activation of these TLRs results in the production of inflammatory cytokines and type I interferon. Genome-wide association studies, single nucleotide polymorphism analyses as well as experimental mouse models have provided evidence of TLR signaling involvement in SLE and other autoimmune diseases. …”
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Towards Multitarget Testing in Molecular Microbiology by Deborah Steensels, Anne Vankeerberghen, Hans De Beenhouwer

“…They are particularly useful when patient treatment has already been initiated or for specimens that may contain microorganisms that are slow-growing, difficult to culture, or for which culture methods do not exist. However, due to genome variability, single target testing might lead to false-negative results. …”
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An Interstitial 4q Deletion with a Mosaic Complementary Ring Chromosome in a Child with Dysmorphism, Linear Skin Pigmentation, and Hepatomegaly by J. Carter, H. Brittain, D. Morrogh, N. Lench, J. J. Waters

“…Interstitial deletions of 4q are rarely reported, vary in size, and have limited genotype-phenotype correlations. Here, genome-wide array CGH analysis identified a 21.6 Mb region of copy number loss at 4q12-q21.1 in a patient diagnosed with dysmorphism, linear skin pigmentation, and hepatomegaly. …”
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Algebraic and topological indices of molecular pathway networks in human cancers by Peter Hinow, Edward A. Rietman, Sara Ibrahim Omar, Jack A. Tuszyński

“…Protein-protein interaction networks associated with diseases have gained prominence as an area of research.We investigate algebraic and topological indices for protein-protein interaction networks of 11 human cancers derived from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. We find a strong correlationbetween relative automorphism group sizes and topological network complexities on the one hand and five year survival probabilities on the other hand. …”
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Analysis of Protein-Ligand Interactions of SARS-CoV-2 Against Selective Drug Using Deep Neural Networks by Natarajan Yuvaraj, Kannan Srihari, Selvaraj Chandragandhi, Rajan Arshath Raja, Gaurav Dhiman, Amandeep Kaur

“…The DNN senses the response of protein-ligand interactions for a specific drug and identifies which drug makes the interaction that combats effectively the virus. With limited genome sequence of Indian patients submitted to the GISAID database, we find that the DNN system is effective in identifying the protein-ligand interactions for a specific drug.…”
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The treasure trove of yeast genera and species described by Johannes van der Walt (1925-2011) by Maudy Th. Smith, Marizeth Groenewald

“…This pioneering work led to the discovery of many new genera and species, which were deposited in the Centraalbureau voor Schimmelcultures (CBS) collections for future studies in taxonomy, genomics, and industrial uses. These treasures collected during more than 60 years provide an outstanding legacy to the yeast community and will continue to exist in his absence. …”
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THE SUITABILITY OF THE BMY2 AND WAXY GENES AND INTERNAL TRANSCRIBED SPACERS OF RRNA AS MARKERS FOR STUDYING GENETIC VARIABILITY IN ELYMUS SPECIES by N. A. Shmakov, D. A. Afonnikov, P. A. Belavin, A. V. Agafonov

“…This variation makes it useful in investigating the genome constitutions of novel Elymus species. Finally, systematical status of E. kamczadalorum as a species was proven valid.…”
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Recent Advances in Antimicrobial Resistance: Insights from <i>Escherichia coli</i> as a Model Organism by Zhaoyang Zhang, Minliang Wei, Bin Jia, Yingjin Yuan

“…This review explores recent advances for investigating AMR in <i>E. coli</i>, including machine learning for resistance pattern analysis, laboratory evolution to generate resistant mutants, mutant library construction, and genome sequencing for in-depth characterization. Key resistance mechanisms are discussed, including drug inactivation, target modification, altered transport, and metabolic adaptation. …”
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Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence by Patrycja Kozubek, Julia Kuźniar, Magdalena Czaja, Hanna Sitka, Urszula Kochman, Jerzy Leszek

“…They make up roughly 8% of the human genome. HERVs exhibit many physiological and non-physiological functions; for example, they play a role in the development of many diseases. …”
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Methylated RNA Immunoprecipitation Sequencing Reveals the m6A Landscape in Oral Squamous Cell Carcinoma by Xi Wang, Jie Wu, Leyu Zhang, Wei Zhao, Jiayin Deng

“…The m6A peaks are always distributed in the junction of the 3′-untranslated regions (3′-UTRs) and the coding sequences (CDS) of mRNAs, as well as the entire genome of long noncoding RNA (lncRNA). Furthermore, enrichment analysis showed that differentially methylated genes were significantly enriched in NF-kappa B signaling pathway, Hedgehog signaling pathway, etc. …”
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Canadian perspectives on food security and plant breeding by Claire Williams, Savannah Gleim, Stuart J. Smyth

“…Conclusions Canadians lack basic knowledge about modern plant breeding practices and technologies and possess high levels of uncertainty regarding the potential for benefits or externalities to develop from the commercialization of new genome editing plant breeding technologies.…”
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Analytical validation of the IBD segment-based tool KinSNP® for human identification applications by Bruce Budowle, Jianye Ge, Lee Baker, Kristen Mittelman, David Mittelman

“…Herein, the tool was validated using simulated pedigree data (up to 9th degree relationships) from five diverse populations from the 1000 Genomes Project. Performance was further tested under conditions of simulated genotyping errors and allele or locus dropout. …”
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Apiospora arundinis, a panoply of carbohydrate-active enzymes and secondary metabolites by Trine Sørensen, Celine Petersen, Asmus T. Muurmann, Johan V. Christiansen, Mathias L. Brundtø, Christina K. Overgaard, Anders T. Boysen, Rasmus D. Wollenberg, Thomas O. Larsen, Jens L. Sørensen, Kåre L. Nielsen, Teis E. Sondergaard

“…In this study, we present the first genome assembly of an Apiospora arundinis isolate, demonstrating a highly complete and contiguous assembly estimated to 48.8 Mb, with an N99 of 3.0 Mb. …”
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CHST1 as a prognostic-related biomarker in gastric cancer correlating with immune infiltration by Long Gui, Jin-hao Yu, Jia-nan Tan, Guang-yu Zhong, Yong-xue Wang, Lin Zhong, Jiao-jiao Su, Dong Hou, Bin Yang, Fang-hai Han, Sheng-ning Zhou

“…In this study, we obtained the transcriptional profile and corresponding clinical information of CHST1 in gastric cancer (GC) tissues and normal tissues from The Cancer Genome Atlas database. Our functional experiments have demonstrated that CHST1 enhances the proliferation and metastasis of GC cells, both in vitro and in vivo. …”
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Modern and future forestry based on biotechnology by Shihui Niu, Jihua Ding, Changzheng Xu, Jing Wang

“…In the last 2 decades, advances in biotechnologies such as high‐throughput sequencing and genome editing are transforming tree breeding and forestry. …”
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Genetic Diversity Analysis of Mulberry Silkworm (Bombyx Mori L.) Hybrids and Breeds in Azerbaijan Using RAPD Markers by Mammadov Ayaz, Aghayeva Saltanat, Bakırov Guduret, Gulubeyova Mahpuba, Ismayılova Gular

“…For this purpose, silkworm larvae were taken for DNA extraction and nuclear genome DNA was isolated from various parts of the silkworm (silk gland, epidermis, etc.). …”
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Development of the genetic classification of Aegilops columnaris Zhuk. chromosomes based on the analysis of introgression lines Triticum aestivum×Ae. columnaris by A. A. Shishkina, A. Yu. Dragovich, A. S. Rouban, S. N. Sibikeev, A. E. Druzhin, E. D. Badaeva

“…In addition, another Aegilops chromosome has been found in the line 2305/1 as a monosomic addition; due to the lack of group-specific markers we were unable to assign this chromosome to a particular genome or a genetic group and therefore it was designated Ае-а. …”
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