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3461
The relationship of lamins with epigenetic factors during aging
Published 2022-03-01“…The key factor of genome instability during aging is transposon dysregulation. …”
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3462
Mining Prognostic Biomarkers of Thyroid Cancer Patients Based on the Immune-Related Genes and Development of a Reliable Prognostic Risk Model
Published 2023-01-01“…According to The Cancer Genome Atlas (TCGA) cohort, we developed a least absolute shrinkage and selection operator (LASSO) regression prognostic model and performed validation analyses regard to the predictive value of the model in internal (TCGA) and external (International Cancer Genome Consortium) cohorts respectively. …”
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3463
Identification of two new genetic loci for high-resolution genotyping of Enterocytozoon bieneusi
Published 2025-01-01“…In this study, comparison of a clinical genome sequence (C44566) with the whole genome sequence of an E. bieneusi isolate (H348) in GenBank led to the selection of the hypothetical protein 1 (hp1) and tubulin 1 (tub1) loci. …”
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3464
Epidemiological monitoring of avian influenza in the Republic of Crimea in 2019–2020
Published 2021-11-01“…In 2019, the AIV type A (H9) genome was detected in one fecal sample taken from wild birds near Kuchuk-Adzhigol Lake in Feodosia Urban Okrug. …”
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3465
Interspecific hybridization of potato: theoretical and applied aspects
Published 2017-03-01“…To date, molecular genetics, genomics, and biotechnology have accumulated a large amount of information, allowing the problems of extension of the genetic diversity of common potato to be addressed. …”
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3466
Mendelian randomization analysis of the causal relationship between trimethylamine N-oxide and its precursors and Parkinson’s disease
Published 2024-12-01“…Material and methods We aggregated data from three genome-wide association studies (International Parkinson’s Disease Genomics Consortium, Parkinson’s Research: The Organized Genetics Initiative and GenePD, and FinnGen) to extract single-nucleotide polymorphisms (SNPs) associated with circulating concentrations of TMAO, choline, carnitine, and betaine. …”
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3467
GmERF57 negatively regulates root development and phosphate absorption in soybean
Published 2025-03-01“…Previously, we identified soybean Ethylene Response Factor 57 (GmERF57) as a candidate gene responsible for q20, a major QTL associated with soybean low Pi (LP) tolerance-related traits identified through QTL mapping and genome-wide association analysis (GWAS). Population genomics analysis revealed that GmERF57 has undergone artificial selection, and allelic distribution analysis significantly correlated with traits associated with LP tolerance in soybean. …”
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3468
Modern issues of sugar beet (<i>Beta vulgaris</i> L.) hybrid breeding
Published 2021-07-01“…It has been found that DNA markers of the sugar beet mitochondrial genome belonging to the TR minisatellite family (TR1 and TR3) enable reliable enough identification of haploid microclonal plants as MSor O-type forms. …”
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3469
Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein.
Published 2025-01-01“…We recently characterized homeobox protein MSX-1 (MSX1) as a host restriction factor that inhibits HBV gene expression and genome replication by directly binding to HBV enhancer II/core promoter (EnII/Cp) and suppressing its promoter and enhancer activities. …”
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3470
Pan-cancer analysis and single-cell analysis identifies the CENPN as a biomarker for survival prognosis and immunotherapy
Published 2025-01-01“…Methods Investigate the role of CENPN in various malignancies, we leveraged data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases. …”
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3471
Current concepts in the pathogenesis of spondyloarthritis
Published 2020-01-01“…The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us understand and postulate various theories. …”
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3472
Diagnostic Role of Chromosomal Instability in Melanoma
Published 2012-01-01“…Chromosomal instability (CIN) is a hallmark of cancer and is markedly prevalent in melanoma. Advances in genomics have opened the door for the development of molecular tools to better segregate benign and malignant lesions. …”
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3473
Advances in lignocellulosic feedstocks for bioenergy and bioproducts
Published 2025-02-01“…It also explores emerging biotechnologies such as CRISPR-based genome editing informed by machine learning, aimed at improving feedstock traits and reducing the environmental impact of fossil fuel dependence.…”
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3474
The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes
Published 2014-01-01“…This is because protein components of the RC are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis and maintenance of mitochondria, including mitochondrial DNA (mtDNA) replication, transcription, and translation, require nuclear-encoded genes. …”
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3475
Novel Roles of the Picornaviral 3D Polymerase in Viral Pathogenesis
Published 2010-01-01“…The RNA-dependent RNA-polymerase, 3Dpol, is an essential component in the picornavirus genome for the replication of single stranded RNA. …”
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3476
The Zebrafish model in dermatology: an update for clinicians
Published 2022-06-01“…Several studies have proved that there is a high level of similarity between human and zebrafish genomes, which encourages the use of zebrafish as a model for understanding human genetic disorders, including cancer. …”
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3477
Role of FTO in Adipocyte Development and Function: Recent Insights
Published 2015-01-01“…In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with obesity in humans. …”
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3478
Dermatophyte Virulence Factors: Identifying and Analyzing Genes That May Contribute to Chronic or Acute Skin Infections
Published 2012-01-01“…The recent availability of genome sequence information and improved genetic manipulation have enabled researchers to begin to identify and study the role of virulence factors of dermatophytes. …”
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3479
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3480
Data on insect biodiversity in a Chinese potato agroecosystem from DNA metabarcoding
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