RNA splicing: a split consensus reveals two major 5′ splice site classes by Matthew T. Parker, Sebastian M. Fica, Gordon G. Simpson

“…The two 5′ splice site classes are separable in genome sequences, sensitized by specific genotypes and associated with splicing complexity. …”
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Different Genotypes of the Rare and Threatened Moss <i>Physcomitrium eurystomum</i> (Funariaceae) Exhibit Different Resilience to Zinc and Copper Stress by Djordje P. Božović, Marija V. Ćosić, Vladislav Kolarčik, Michal Goga, Claudio Varotto, Mingai Li, Aneta D. Sabovljević, Marko S. Sabovljević

“…Flow cytometry analyses revealed that the two accessions differ significantly in terms of genome size. However, the different amplitude of resilience to the tested PTEs, the divergence in physiological responses, and survival within two accessions of the same species are confirmed, as well as the dissimilarity of their genome size, likely associated with ploidy level difference and possibly distinct hybrid origin.…”
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Cardiovascular Effects Mediated by HMMR and CD44 by Kinga Jaskuła, Mariusz Sacharczuk, Zbigniew Gaciong, Dominik S. Skiba

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Microbiome and Colorectal Cancer in Humans: A Review of Recent Studies by Hiroyuki Takamaru, Cynthia Tsay, Satoshi Shiba, Shinichi Yachida, Yutaka Saito

“…In recent years, metagenomic techniques such as shotgun sequencing and genome-wide association studies focused on understanding the role of the microbiota and the metabolome on early CRCs and colon carcinogenesis to determine if there are modifiable or intervenable targets for CRC. …”
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Construction and efficacy of recombinant Newcastle disease virus co-expressing VP2 and VP3 proteins of very virulent infectious bursal disease virus by Tongfei Liu, Lin Lin, Yun Pan, Xiaoling Lin, Ming Liang, Guanming Shao, Keyu Feng, Yaxin Liu, Xinheng Zhang, Qingmei Xie

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Two Sides of the Same Coin: TFIIH Complexes in Transcription and DNA Repair by Alexander Zhovmer, Valentyn Oksenych, Frédéric Coin

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Artificial intelligence across oncology specialties: current applications and emerging tools by Frank Lin, Tim Rattay, John Kang, Evangelia Katsoulakis, Kyle Lafata, Ellen Kim, Christopher Yao, Harsha Nori, Christoph Ilsuk Lee

“…In this review, we provide multidisciplinary perspectives on oncology applications touched by AI—imaging, pathology, patient triage, radiotherapy, genomics-driven therapy and surgery—and integration with existing tools—natural language processing, digital twins and clinical informatics.…”
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Peroxisome Proliferator-Activated Receptor Alpha Target Genes by Maryam Rakhshandehroo, Bianca Knoch, Michael Müller, Sander Kersten

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Synthesis, antimycobacterial and antifungal evaluation of new 4-(furan-2-ylmethyl)-6-methylpyridazin-3(2H)-ones by Karayavuz Burcu, Vagolu Siva Krishna, Kart Didem, Tønjum Tone, Unsal-Tan Oya

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Protocol for direct cDNA cap analysis of gene expression for paired-end patterned flow cell sequencing by Diane Delobel, Hiromi Nishiyori-Sueki, Ilaria Nisoli, Hideya Kawaji, Pauline Robbe, Piero Carninci, Hazuki Takahashi

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Trajectory of human migration: insights from autosomal and non-autosomal variant clustering patterns by Samayeta Sarkar Tuli, Joyatry Sarker, Mrinmoy Saha Roddur, Anik Biswas, Reefa Nawar, Tahmina Akter, Md. Wahid Murad, Abu Ashfaqur Sajib

“…Moreover, the genetic markers on the Y chromosome constitute only a minor fraction of the entire human genome. Here, we analyzed over 75 million genetic variants (single nucleotide variants (SNVs) and short insertion-deletion (InDels)) within consecutive 2500000 base pair windows in the autosomal as well as non-autosomal chromosomes of 22 populations in four major geographic regions that are cataloged in the 1000 Genomes Project to understand the clustering patterns of the autosomal and non-autosomal variants. …”
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Determination of the copy numbers of type A porcine endogenous retroviruses in domestic pigs and wild boars by R. B. Aitnazarov, N. S. Yudin, R. S. Kiril’chuk, N. N. Kochnev, S. P. Knyazev, M. I. Voevoda

“…Thus, the Siberian minipig genome has a considerable number of type A PERVs, conceivably pathogenic to humans. …”
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DNA methylation and its influence on the pathogenesis of osteoarthritis: a systematic literature review by Thomas Nau, Samira Cutts, Nerissa Naidoo

“…Others reported on the association between OA risk genes and DNA methylation. Genome-wide methylation studies reported on differentially methylated regions (DMRs) comparing OA and non-OA chondrocytes. …”
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Ophthalmomyiasis Case Caused by Two Blow Fly (Diptera: Calliphoridae) Species in North America by Taylor B. Parker, Kelly A. Meiklejohn, Gregory A. Dahlem, Ralph C. Eagle, Marius J. Heersink

“…A representative subsample of five larvae was used for taxonomic identification via two approaches (a) DNA analysis, via sequencing of the complete mitochondrial genome (mtGenome) and comparison of the mtGenome and mitochondrial COI barcode region to GenBank, and (b) morphology, examination of the posterior spiracles using microscopy, and comparison to published larval descriptions of blow flies. …”
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The role of transposable elements in the ecological morphogenesis under the influence of stress by R. N. Mustafin, E. K. Khusnutdinova

“…In natural selection, insertional mutagenesis is an important source of genome variability. Transposons are sensors of environmental stress effects, which contribute to adaptation and speciation. …”
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Evaluation of Recombinant Antibody Production Efficiency in CHO Cells with Sleeping Beauty Transposon Vector System by Pelin Kolçak Yaşlı, Seda Kulabaş, Evren Doruk Engin

“…Different transfection systems are employed for the integration of the target gene cassette into the cell genome and have limitations, such as (i) the integration region in the genome, (ii) the size of the target cassette, and (iii) long selection periods for stable expression. …”
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AAV-based vectors for human diseases modeling in laboratory animals by Timur I. Aliev, Dmitry V. Yudkin

“…This review analyzes the features of the adeno-associated virus genome that make it an advantageous vector for transgenesis. …”
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Effects of farming specialisation on grassland birds in Mediterranean High Nature Value farmland by Joana Santana, Pedro J. Leitão, Paulo Flores Ribeiro, Pedro Beja, Ângela Lomba, Rui Pedroso, Rui Morgado, Ricardo C. Martins, Inês Catry, Ana Teresa Marques, Luís Reino, Francisco Moreira

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Table for two: Diet composition differences of allopatric and sympatric populations of island geckos by Catarina J. Pinho, Bárbara Santos, Vanessa A. Mata, Ricardo J. Lopes, Maria M. Romeiras, Evandro P. Lopes, Paulo C. Alves, Brent C. Emerson, Raquel Vasconcelos

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Association between BDNF rs6265 and Obesity in the Boston Puerto Rican Health Study by Xian-Yong Ma, Wei Qiao Qiu, Caren E. Smith, Laurence D. Parnell, Zong-Yong Jiang, Jose M. Ordovas, Katherine L. Tucker, Chao-Qiang Lai

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