Machine learning based predictive model and genetic mutation landscape for high-grade colorectal neuroendocrine carcinoma: a SEER database analysis with external validation by Ruixin Wu, Ruixin Wu, Sihao Chen, Sihao Chen, Yi He, Yi He, Ya Li, Song Mu, Aishun Jin, Aishun Jin

“…This study was designed to construct a risk model based on comprehensive clinical and mutational genomics data to facilitate clinical decision making.MethodsA retrospective analysis was conducted using data from the Surveillance, Epidemiology, and End Results (SEER) database, spanning 2000 to 2019. …”
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A Rare Case of Severe Congenital RYR1-Associated Myopathy by Nicola Laforgia, Manuela Capozza, Lucrezia De Cosmo, Antonio Di Mauro, Maria Elisabetta Baldassarre, Francesca Mercadante, Anna Laura Torella, Vincenzo Nigro, Nicoletta Resta

“…This report confirms that early diagnosis and accurate study of genomic disorders are very important, enabling proper genetic counselling of the reproductive risk, as well as disease prognosis and patient management.…”
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Habitat fragmentation increases the risk of local extinction of small reptiles: A case study on Phrynocephalus przewalskii by Cui Yang, Yue Qi, Jiayuan Guo, Liangfei Peng, Neng Xiong, Wenya Zhang, Wei Zhao

“…Results showed that individuals in highly fragmented areas exhibited smaller body size, higher reproductive investment, and lower genetic diversity. Genomic analyses revealed significantly fewer SNPs, INDELs, and SVs in the highly fragmented area compared to others, with the slowest linkage disequilibrium decay rate, indicating strong environmental pressure. …”
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Antagonism of Eucalyptus endophytic fungi against some important crop fungal diseases by Parmida Aleahmad, Leila Ebrahimi, Naser Safaie, Hassan Reza Etebarian

“…Lastly, the selected isolates were identified as Trichoderma longibrachiatum KL1, T. longibrachiatum 8S1, Chaetomium globosum DL4, Phaeophleospora eucalypticola XL4, and Pseudosydowia eucalypti VL3 based on their morphological features and molecular data of the ITS1-5.8S-ITS2 and tef-1α genomic regions.…”
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Comparative analysis of the inheritance of a high development rate in the Rimax and Rico lines of spring bread wheat (<i>Triticum aestivum</i> L.) by B. V. Rigin, Е. V. Zuev, А. S. Andreeva, I. I. Matvienko, Z. S. Pyzhenkova

“…Alleles of the Vrn and Ppd genes were identified by PCR according to known publications, and genomic DNA was isolated from 3-day-old seedlings by the CTAB method.Results. …”
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Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype. by Florence E McLean, Brian R Omondi, Nouhoum Diallo, Stanley Otoboh, Carolyne Kifude, Abdirahman I Abdi, Rivka Lim, Thomas D Otto, Ashfaq Ghumra, J Alexandra Rowe

“…However, making functional sense of genomic data relies on the ability to infer binding phenotype from var gene sequence. …”
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Classifications of triple-negative breast cancer: insights and current therapeutic approaches by Ziqi Chen, Yumeng Liu, Minchuan Lyu, Chi Ho Chan, Meiheng Sun, Xin Yang, Shuangying Qiao, Zheng Chen, Sifan Yu, Meishen Ren, Aiping Lu, Ge Zhang, Fangfei Li, Yuanyuan Yu

“…Additionally, TNBC exhibits significant heterogeneity at histopathological, proteomic, transcriptomic, and genomic levels, further complicating the development of effective treatments. …”
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Newcastle disease virus genotype VII.1.1 identified from backyard chickens with low antibody titer: Jimma Zone, Southwest Ethiopia. by Bezina Arega Emeru, Haregawi Tesfaye Desta, Yosef Deneke

“…From the swab samples, total RNA was extracted and the viral genomic material was detected by amplifying the Fusion gene by Reverse transcription polymerase chain reaction (RT-PCR). …”
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The Construction of Heterothallic Strains of <i>Komagataella kurtzmanii</i> Using the I-SceI Meganuclease by Daria D. Sokolova, Philipp I. Akentyev, Kristina O. Petrova, Lyudmila V. Lyutova, Aleksei A. Korzhenkov, Irek I. Gubaidullin, Stepan V. Toshchakov, Dmitry G. Kozlov

“…The results of PCR and whole genome analysis confirmed the identity of the contents of the MAT loci. …”
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Characterization of demethylating DNA glycosylase ROS1 from Nicotiana tabacum L. by D. V. Petrova, N. V. Permyakova, I. R. Grin, D. O. Zharkov

“…Expression of the NtROS1 gene in cultured human cells resulted in a global decrease in the level of genomic DNA methylation. In general, it can be said that the NtROS1 protein and other homologues of DME and ROS1 represent a promising scaffold for engineering enzymes to analyze the status of epigenetic methylation and to control gene activity.…”
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Genetic diversity, population structure in a historical panel of Brazilian soybean cultivars. by Adriel Carlos da Silva, Danielle C Gregorio da Silva, Everton Geraldo Capote Ferreira, Ricardo V Abdelnoor, Aluízio Borém, Carlos Arrabal Arias, Marcelo F Oliveira, Marcio Elias F de Oliveira, Francismar Corrêa Marcelino-Guimarães

“…This finding is consistent with the history of soybean expansion in Brazil. We identified 123 genomic regions under selection among the groups of Brazilian cultivars associated with 440 quantitative trait loci (QTLs), revealing regions fixed across the breeding process associated with yield, disease resistance, water efficiency use, and others.…”
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Genetic Evidence of Killer Whale Predation on White Sharks in Australia by Isabella M. M. Reeves, Andrew R. Weeks, Alison V. Towner, Rachael Impey, Jessica J. Fish, Zach S. R. Clark, Paul A. Butcher, Lauren Meyer, David M. Donnelly, Charlie Huveneers, Nicky Hudson, Adam D. Miller

“…Visual inspection of the carcass revealed that the liver, digestive, and reproductive organs were missing, and the presence of four distinctive bite wounds, one of which was characteristic of killer whale liver extraction as seen in South Africa. Genomic analyses performed on swabs taken from the bite wounds confirmed the presence of killer whale DNA in the major bite area, while the other bites were embedded with genetic material from the scavenging broadnose sevengill shark (Notorynchus cepedianus). …”
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Characterization and functional analysis of chicken hnRNP protein by Ke Wang, Manzi Huang, Qinghua Zeng, Huansheng Wu

“…In this study, multiple chicken hnRNPs were identified to interact with genomic dsRNA. Initially, these hnRNPs were found to be exclusively localized in the nucleus before IBDV infection. …”
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Development of a Loop Mediated Isothermal Amplification for Diagnosis of Ascaris lumbricoides in Fecal Samples by Esther A. Shiraho, Agola L. Eric, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku, Robert M. Mugambi, Jackson M. Mwandi, Gerald M. Mkoji

“…Ascaris adult and ova were obtained from naturally infected school children, whose parents/guardians gave consent for their participation in the study. Genomic DNA was extracted using alkaline lysis method and amplified by LAMP at 63°C for 45 minutes. …”
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Defining patient-reported outcomes in diabetes, obesity, cardiovascular disease, and chronic kidney disease for clinical practice guidelines - perspectives of the taskforce of the... by Katharine Barnard-Kelly, Tadej Battelino, Frank C. Brosius, Antonio Ceriello, Francesco Cosentino, James R. Gavin, Francesco Giorgino, Jennifer Green, Linong Ji, Monika Kellerer, Sue Koob, Mikhail Kosiborod, Nebojsa Lalic, Nikolaus Marx, Prashant Nedungadi, Christopher G. Parkin, Helena W. Rodbard, René D. Rötzer, Lars Rydén, Wayne Huey-Herng Sheu, Eberhard Standl, Britta Tendal Jeppesen, Pinar Topsever, Per Olav Vandvik, Christoph Wanner, Oliver Schnell

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Identification of Microbial and Proteomic Biomarkers in Early Childhood Caries by Thomas C. Hart, Patricia M. Corby, Milos Hauskrecht, Ok Hee Ryu, Richard Pelikan, Michal Valko, Maria B. Oliveira, Gerald T. Hoehn, Walter A. Bretz

“…The purpose of this study was to provide a univariate and multivariate analysis of genomic microbial data and salivary mass-spectrometry proteomic profiles for dental caries outcomes. …”
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G-quadruplex-forming small RNA inhibits coronavirus and influenza A virus replication by Ryoya Sekine, Kouki Takeda, Tsukasa Suenaga, Satsuki Tsuno, Takumi Kaiya, Maki Kiso, Seiya Yamayoshi, Yoshihide Takaku, Shiho Ohno, Yoshiki Yamaguchi, Seiichi Nishizawa, Kazuhiro Sumitomo, Kazufumi Ikuta, Teru Kanda, Yoshihiro Kawaoka, Hidekazu Nishimura, Shusuke Kuge

“…Unlike previous antiviral strategies that target the G-quadruplexes of the viral genome, we now show that excess exogenous G-quadruplex-forming small RNA displaces genomic RNA from ribonucleoprotein, effectively inhibiting viral replication. …”
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Association of Plasma Levels of Nitric Oxide Oxidative Metabolites with Acute Stroke in Patients Presenting to the Emergency Department of a Low-Middle Income Country by Shahan Waheed, Ayaz Ghouse Kalsekar, Ayeesha Kamran Kamal, Nathan S. Bryan, Asad I. Mian

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Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02 by Gwendolin S. Simper, Gia-Gia T. Hò, Alexander A. Celik, Trevor Huyton, Joachim Kuhn, Heike Kunze-Schumacher, Rainer Blasczyk, Christina Bade-Döding

“…The HLA allele B∗15:02 has been described to be a genomic biomarker for CBZ-mediated immune reactions. …”
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RETRACTED ARTICLE: Construction and validation of a machine learning-based immune-related prognostic model for glioma by Qi Mao, Zhi Qiao, Qiang Wang, Wei Zhao, Haitao Ju

“…The model genes were further studied using GSCA, TISCH2, and HPA databases to understand their role in glioma pathology at the genomic, molecular, and single-cell levels, and validate the biological function of IKBKE in vitro experiments. …”
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