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2661
Epigenetic Properties of Compounds Contained in Functional Foods Against Cancer
Published 2024-12-01“…Epigenetics encompasses reversible and heritable genomic changes in histones, DNA expression, and non-coding RNAs that occur without modifying the nucleotide DNA sequence. …”
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2662
Detection of Chromosome X;18 Breakpoints and Translocation of the Xq22.3;18q23 Regions Resulting in Variable Fertility Phenotypes
Published 2012-01-01“…Maternal inheritance and various genomic events contributed to the resultant genotypes. …”
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2663
A TaqMan Real-Time PCR Assay for Detection and Quantification of Sporisorium scitamineum in Sugarcane
Published 2013-01-01“…This method was more sensitive (a detection limit of 10 ag pbE DNA and 0.8 ng sugarcane genomic DNA) than that of conventional PCR (10 fg and 100 ng, resp.). …”
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2664
Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells
Published 2025-01-01“…Aurora Kinase A is a major mitotic protein kinase that regulates mitotic progression; overexpression and hyperactivation of AURKA commonly promote genomic instability in many tumours. However, the relationship of functional residues of AURKA and EBV in gastric cancer progression remains unknown. …”
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2665
Biological peculiarities and cultivation of groundnut (a review)
Published 2020-04-01“…Diploid species contain 2n = 20 chromosomes of the A, B or D genome, tetraploids have A and B genomes. The А and В genomes are sequenced. …”
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2666
Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptides from Plants: Structures, Therapeutic Potential, and Future Directions
Published 2024-12-01“…By integrating traditional ethnobotanical knowledge with modern genomic and bioinformatic approaches, this study underscores the importance of plant RiPPs as a resource for developing innovative cancer treatments. …”
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2667
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2668
Opportunities for promoting open data in the Caribbean through biobanks
Published 2025-02-01“…It offers unprecedented insights into health data through extensive follow up and collection of genome-wide genotype data. H3Africa focuses on genomics research that addresses health disparities among African populations, which parallels the Caribbean’s challenges. …”
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2669
Shallow-water mussels (Mytilus galloprovincialis) adapt to deep-sea environment through transcriptomic and metagenomic insights
Published 2025-01-01“…Abstract Recent studies have unveiled the deep sea as a rich biosphere, populated by species descended from shallow-water ancestors post-mass extinctions. Research on genomic evolution and microbial symbiosis has shed light on how these species thrive in extreme deep-sea conditions. …”
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2670
Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A
Published 2020-01-01“…In this study, the impact of nsSNPs in the ATL1 gene was investigated by various in silico tools that revealed five nsSNPs (V67F, T120I, R217Q, R495W, and G504E) are deleterious SNPs, which have a functional impact on ATL1 protein and, therefore, can be used as genomic biomarkers specifically before 4 years of age; also, it may play a key role in pharmacogenomics by evaluating drug response for this disabling disease.…”
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2671
Molecular Characterization and Expression of <i>unc-13d</i> in the Sex Reversal of <i>Monopterus albus</i>
Published 2025-01-01“…</i> We found that the genomic structure of <i>unc-13d</i> was different from other species. …”
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2672
Deciphering the nature and statistical optimization of antimicrobial metabolites of two endophytic bacilli
Published 2025-01-01“…Both bacterial isolates displayed antioxidant and antiviral activity and mild cytotoxic action. Genomic sequence and antiSMASH analysis showed that the biosynthetic gene clusters of bacillomycin, mycosubtilin, fengycin, and macrolactin H in B. velezensis CCASU-C6 and bacillibactin and Macrolactin H in B. subtilis CCASU-C11 showed 100% conservation.…”
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2673
Intraspecific diversity of durum wheat (Triticum durum Desf.): a unif ied classif ication
Published 2021-06-01“…., which is based on the genomic composition of species and the presence or absence of a number of main genes that govern the “classification” traits. …”
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2674
The technology landscape for detection of DNA methylation in cancer liquid biopsies
Published 2025-12-01“…The first methods were established for DNA methylation detection in genomic DNA, while new methods have focused more on compatibility with the emerging interest of cell-free DNA (cfDNA) from liquid biopsies. …”
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2675
Multi-gene precision editing tool using CRISPR-Cas12a/Cpf1 system in Ogataea polymorpha
Published 2025-01-01“…However, the lack of precise and efficient genome editing tools severely hinders the construction of cell factories. …”
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2676
Multiple Organ Failure Associated with SARS-CoV-2 Infection in a Child with Down Syndrome: Is Trisomy 21 Associated with an Unfavourable Clinical Course?
Published 2021-01-01“…Down syndrome (DS) is one of the most frequent genomic disorders around the globe (∼1:700 births). …”
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2677
Microbial signatures in head and neck squamous cell carcinoma: an in silico study
Published 2025-02-01“…Conclusion The oral-gut microbial dysbiosis, as reflected by the differential abundance of bacterial species in oral and GI carcinomas, suggests the implication of tumor microbiome and their genomic interactions with the host in carcinogenesis.…”
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2678
Polymorphism of monogenic scab resistance loci in apple varieties
Published 2020-04-01“…Biological material was represented by apple cultivars of different environmental and geographical origin. Total genomic DNA was extracted from fresh leaves using CTAB methods according to the DArT protocols. …”
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2679
Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads?
Published 2019-01-01“…It is because of technical advances in isolation, fermentation, spectroscopy, and genomic studies which led to the efficient recovering of Streptomyces and their new chemical compounds with distinct activities. …”
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2680
Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B Streptococcus
Published 2008-01-01“…We used microarray-based comparative genomic hybridization to identify open reading frames (ORFs) present in two sequenced invasive strains, but absent or divergent in tester strains. …”
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