Association of Androgen-Receptor Gene Mutations with the Copy Number of Androgen-Receptor Silk Protein A Complex and Glutathione-S-Transferases T1 and M1 in Prostate Cancer Patient... by Yan Zhang, Xiangdi Meng, Zhaosen Ma, Zhou Sun, Zhixin Wang

“…Fasting peripheral venous blood was collected, whole blood genomic DNA was extracted, and AR gene-receptor genotype was detected by a high-resolution melting curve analysis detection technology. …”
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A New Prognostic Indicator of Immune Microenvironment and Therapeutic Response in Lung Adenocarcinoma Based on Peroxisome-Related Genes by Zhen Xiong, Liwen Zhang, Wei Fan

“…However, the prognostic values of peroxisome-related genes (PRGs) were rarely reported. Genomic sequence, mutation, and clinical data of 535 LUAD tissues were obtained from TCGA data sets. …”
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ADAM-multi: software to simulate complex breeding programs for animals and plants with different ploidy levels and generalized genotypic effect models to account for multiple allel... by Thinh Tuan Chu, Thinh Tuan Chu, Just Jensen

“…Along with the description of the updated simulation model in ADAM-Multi, this paper shows two small-scale studies that investigate the effects of multi-allelic versus bi-allelic assumptions in simulation and the use of different prediction models in a single-population breeding program for potatoes. We found that genomic models using dense bi-allelic markers could effectively predicted breeding values of individuals in a well-structure population despite the presence of multi-allelic QTL. …”
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Integration of circulating tumor DNA in biliary tract cancer: the emerging landscape by Joy A Awosika, Cecilia Monge, Tim F Greten

“…The acquisition of tissue tumor DNA for genomic analysis in BTC is often anatomically challenging, limited by quantity and quality. …”
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Profiling of small RNAs derived from tomato brown rugose fruit virus in infected Solanum lycopersicum plants by deep sequencing by Mangle Chen, Donghai Wang, Jiali Yang, Yuhao Cao, Xuemei Song, Yuwen Lu, Hongying Zheng, Jiejun Peng, Guanwei Wu, Jian Wu, Junmin Li, Jianping Chen, Fei Yan, Shaofei Rao

“…The single-nucleotide resolution profile shows that vsiRNAs exhibit a heterogeneous continuous distribution in the ToBRFV genomic RNA, with hotspot regions on the antisense strand located at the 5′ end of the RdRP and in the coding regions of MP and CP. …”
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Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia by Amal F. Alshammary, Ghada BinSaif, Imran Ali Khan

“…The recruitment was based on the sample size calculation and based on it, we have recruited 300 Saudi individuals who were evenly divided into vitiligo cases and controls. Extracted genomic DNA was utilized to amplify rs231775 and rs3087243 SNPs in the CTLA4 gene, which were subsequently digested and verified using Sanger sequencing. …”
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Predicting metabolite response to dietary intervention using deep learning by Tong Wang, Hannah D. Holscher, Sergei Maslov, Frank B. Hu, Scott T. Weiss, Yang-Yu Liu

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Isolation, identification, and characterisation of the malachite green detoxifying bacterial strain Bacillus pacificus ROC1 and the azoreductase AzrC by Shanza Bibi, Callum W. Breeze, Vusqa Jadoon, Anum Fareed, Alina Syed, Rebecca L. Frkic, Habiba Zaffar, Muhammad Ali, Iftikhar Zeb, Colin J. Jackson, Tatheer Alam Naqvi

“…We demonstrate immobilized B. pacificus ROC1 can effectively detoxify MG, which highlights a potential method for its biodegradation. Genomic sequencing identified three candidate azo-reductases within B. pacificus ROC1 that could be responsible for the MG-degrading activity. …”
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Emerging Marine Nematodes as Model Organisms: Which Species for Which Question? by Federica Semprucci, Eleonora Grassi, Adele Cocozza di Montanara, Roberto Sandulli, Elisa Baldrighi

“…., emerge as leading candidates due to their manageable life cycles, adaptability to laboratory conditions, and available genomic resources. These tiny organisms provide valuable insights into phenomena such as developmental plasticity, epigenetic regulation, and adaptive responses to environmental stress. …”
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Etiopathogenesis of Sheehan’s Syndrome: Roles of Coagulation Factors and TNF-Alpha by Halit Diri, Elif Funda Sener, Fahri Bayram, Nazife Tascioglu, Yasin Simsek, Munis Dundar

“…Standard methods were used to extract the genomic DNAs. Factor II (G20210A), Factor V (G1691A), and MTHFR (C677T and A1298C) polymorphisms were identified by real-time PCR. …”
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Nano-technological advancements in multimodal diagnosis and treatment by Dinesh Bhatia, Tania Acharjee, Shruti Shukla, Monika Bhatia

“…Similarly, in CVD, NPs target arterial plaques to improve treatment accuracy while reducing systemic adverse effects. Furthermore, the genomic “blueprint” is evolving parallel to nanotechnology, with India's “Genome India” initiative mapping 10,000 genomes, lighting the path for genetic chips suited for specific disorders and moment tests. …”
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Pea (Pisum sativum L.): the uneasy fate of the first genetical object by O. E. Kosterin

“…Meanwhile, we await the completion of pea nuclear genome sequencing in 2016. For working out new molecular markers in pea, the synteny of its genome to the sequenced genome of Medicago truncatula is extensively used. …”
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TopoQual polishes circular consensus sequencing data and accurately predicts quality scores by Minindu Weerakoon, Sangjin Lee, Emily Mitchell, Haynes Heaton

“…Abstract Background Pacific Biosciences (PacBio) circular consensus sequencing (CCS), also known as high fidelity (HiFi) technology, has revolutionized modern genomics by producing long (10 + kb) and highly accurate reads. …”
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Generation of an induced pluripotent stem cell line (UCLi026-A) from a patient with ADCY5-related disease carrying the heterozygous variant c.1253G > A; (p. Arg418Gln) by Sharmin Alhaque, Dimitri Budinger, Barbara Garavaglia, Giovanna Zorzi, Serena Barral, Manju A. Kurian

“…This line was further characterised for pluripotency, differentiation potential and genomic integrity. This cell line, UCLi026-A (UCL-NG-ADCY5-001) can be utilized for in vitro disease modelling of ADCY5-related diseases, as well as for the development of novel therapeutic approaches.…”
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Dynamics of Salmonella Dublin infection and antimicrobial resistance in a dairy herd endemic to salmonellosis. by Victor Santos do Amarante, Joelma Kellen de Castro Pereira, Matheus Ferreira Serafini, Carolina Pantuzza Ramos, Isabela Pádua Zanon, Thayanne Gabryelle Viana de Souza, Tiago Facury Moreira, Antônio Ultimo de Carvalho, Rodrigo Melo Meneses, Flavia Figueira Aburjaile, Vasco Azevedo, Elias Jorge Facury Filho, Rodrigo Otávio Silveira Silva

“…Seven multidrug-resistant isolates were selected for genomic sequencing. Among the resistance determinants identified, a mutation in the gyrA gene, present in all sequenced isolates, was notable. …”
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Ribosomes: An Exciting Avenue in Stem Cell Research by Zhenzhen Han, Qi Zhang, Yanbo Zhu, Jingcheng Chen, Wei Li

“…Stem cell research has focused on genomic studies. However, recent evidence has indicated the involvement of epigenetic regulation in determining the fate of stem cells. …”
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Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta... by Romy Walker, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Julia Como, Susan G. Preston, Sharelle Joseland, Bernard J. Pope, Ana B.D. Medeiros, Brenely V. Murillo, Nicholas Pachter, Kevin Sweet, Allan D. Spigelman, Alexandra Groves, Margaret Gleeson, Krzysztof Bernatowicz, Nicola Poplawski, Lesley Andrews, Emma Healey, Steven Gallinger, Robert C. Grant, Aung K. Win, John L. Hopper, Mark A. Jenkins, Giovana T. Torrezan, Christophe Rosty, Finlay A. Macrae, Ingrid M. Winship, Daniel D. Buchanan, Peter Georgeson

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HER2 expression and pathway status in male breast cancer patients: results of an integrated analysis among 6,150 patients by Boqiang Lyu, Shidi Zhao, Hui Wang, Shouping Gong, Biyuan Wang

“…Altered genes in HER2 + MBC, such as ERBB2, AGO2, RECQL4, and CLTC, were not detected in HER2-MBC. Genomic analysis revealed differences between the patients with HER2 + MBC and those with HER2 + FBC. …”
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The context signals of mitochondrial miRNAs (mitomiRs) of mammals by O. V. Vishnevsky, P. S. Vorozheykin, I. I. Titov

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Multi-Omics Insights into Regulatory Mechanisms Underlying Differential Deposition of Intramuscular and Abdominal Fat in Chickens by Yuxin Xing, Chenglin Ma, Hongbo Guan, Jianing Shen, Ying Shen, Guoxi Li, Guirong Sun, Yadong Tian, Xiangtao Kang, Xiaojun Liu, Hong Li, Weihua Tian

“…This review systematically summarizes the regulatory mechanisms underlying intramuscular and abdominal fat traits at chromatin, genomic, transcriptional, post-transcriptional, translational, and epigenetic-modification scales. …”
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