Cytoplasmic male sterility and prospects for its utilization in breeding, genetic studies and seed production of potato by I. N. Anisimova, T. A. Gavrilenko

“…The main results of research on molecular mechanisms of CMS and fertility restoration obtained in the post-genomic era for various plant species using methods of transcriptomic and proteomic analyses are provided. …”
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Epigenetic Methylation of Parathyroid CaR and VDR Promoters in Experimental Secondary Hyperparathyroidism by Jacob Hofman-Bang, Eva Gravesen, Klaus Olgaard, Ewa Lewin

“…Melting temperature profiling of CaR and VDR PCR products after bisulfite treatment of genomic DNA from rat parathyroids was performed. Real-time PCR measured expression of PTH, CaR, VDR, and klotho genes in vitro. …”
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ADF1 and BEAF-32 chromatin proteins affect nucleosome positioning and DNA decompaction in 61C7/C8 interband region of Drosophila melanogaster polytene chromosomes by M. B. Schwartz (Berkaeva), T. E. Pankova, S. A. Demakov

“…Under these conditions, the genome retains its functionality due to the dynamic and uneven DNA compaction along the chromatin fiber. …”
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Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients by Peizeng Jia, Jianyin Zou, Shankai Yin, Feng Chen, Hongliang Yi, Qian Zhang

“…Saliva was collected from 15 OSAS patients and nine healthy controls, and bacterial genomic DNA was extracted for 16S rRNA amplicon sequencing based on the Illumina platform. …”
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RETRACTED ARTICLE: Screening and identification of susceptibility genes for cervical cancer via bioinformatics analysis and the construction of an mitophagy-related genes diagnosti... by Zhang Zhang, Fangfang Chen, Xiaoxiao Deng

“…Method We initially collected a large amount of genomic data, including gene expression profile and single nucleotide polymorphism (SNP) data, from the control group and Cervical cancer (CC) patients. …”
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Clinical Report of a 17q12 Microdeletion with Additionally Unreported Clinical Features by Jennifer L. Roberts, Stephanie K. Gandomi, Melissa Parra, Ira Lu, Chia-Ling Gau, Majed Dasouki, Merlin G. Butler

“…Subsequently, a 400 K array-based comparative genomic hybridization (aCGH) + SNP analysis was performed which identified a de novo suspected pathogenic deletion on chromosome 17q12 encompassing 28 genes. …”
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Decoding the mechanisms behind second primary cancers by Meiyuan Zeng, Anqi Lin, Aimin Jiang, Zhengang Qiu, Hongman Zhang, Shifu Chen, Mingyan Xu, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo

“…This review summarizes recent studies on the mechanisms of SPCs, including the roles of genomic changes after first primary cancer (FPC) treatments, stromal cell phenotypic and metabolic changes, hormone levels and receptor expression, immunosuppression, aberrant gene methylation, EGFR signaling, and cell-free DNA in SPC development. …”
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Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary by Ulises Urzua, Carlos Chacon, Renato Espinoza, Sebastián Martínez, Nicole Hernandez

“…In addition, the 8-OHdG adduct was evaluated in ovarian genomic DNA. Both hemosiderin and lipofuscin were significantly higher in virgin compared to multiparous ovaries. …”
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Di-Genic Inheritance in Genodermatoses: Insights from Two Consanguineous Cases in a Reference Lebanese Center within the Middle East and North Africa (MENA) Region by Ayat Kadhi, Lamiaa Hamie, Edward Eid, Georges Nemer, Mazen Kurban

“…Conclusion: This study identified novel candidate disease genes and inheritance model that could explain the underlying phenotypes that could open the doors for a better-guided genomic approach for personalized treatment and early diagnosis. …”
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A versatile site-directed gene trap strategy to manipulate gene activity and control gene expression in Caenorhabditis elegans. by Haania Khan, Xinyu Huang, Vishnu Raj, Han Wang

“…Thus, our cGAL-based gene trap is versatile and represents a powerful genetic tool for gene function analysis in C. elegans, which will ultimately provide new insights into how genes in the genome control the biology of an organism.…”
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Corrigendum to Noninflammatory 97-amino acid High Mobility Group Box 1 derived polypeptide disrupts and prevents diverse biofilms. EBioMedicine 107 (2024) by Jaime D. Rhodes, Aishwarya Devaraj, Frank Robledo-Avila, Sabarathnam Balu, Lauren Mashburn-Warren, John R. Buzzo, Santiago Partida-Sanchez, Lauren O. Bakaletz, Steven D. Goodman

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Construction and Antiapoptosis Activities of Recombinant Adenoviral Expression Vector Carrying EBV Latent Membrane Protein 2A by Xishuang Liu, Yu Gao, Bing Luo, Youan Zhao

“…To evaluate the possible effects of LMP2A (EBV latent membrane protein 2A) on human gastric cancer cell line SGC-7901, LMP2A coding gene was subcloned into shuttle plasmid pAdTrackCMV to form transfer plasmid pAdTrackCMV-2A, which was linearized with PmeI and cotransformed into E.coli BJ5183 with adenovirus genomic plasmid of pAdeasy-1. The identified recombinant adenovirus plasmid DNA was digested with PacI and transfected into 293 cells to package recombinant adenovirus particles named vAd-2A. …”
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Expression evaluation of exogenous and endogenous alcohol dehydrogenase genes in transgenic Arabidopsis by Haoqiang Yu, Hong Lv, Fengzhong Lu, Qingqing Yang, Huaming Duan, Wanchen Li, Fengling Fu

“…Three homozygous T3 lines with a single integration site were screened for each of the three transformed genes by antibiotic screening, polymerase chain reaction (PCR) identification, and genomic DNA resequencing. Real-time quantitative PCR (RT-qPCR) analysis showed that the relative expression levels of the transformed exogenous ZmADH and EcADH genes were ten or tens of times higher than that of the transformed endogenous AtADH gene. …”
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Phylogeography and hybridization of corvid birds in the Palearctic Region by A. P. Kryukov

“…We studied mitochondrial and complete genome variation in the bird family Corvidae, genera Corvus, Pica, Cyanopica, Perisoreus and Nucifraga. …”
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Drug repurposing screen for the rare disease ataxia-telangiectasia by Namrata Jayanth, Gurvan Mahé, Matthew Campbell, Mike Lipkin, Shushant Jain, Rhea van de Bospoort, Jennifer Thornton, Brad Margus, David F. Fischer

“…It is caused by bi-allelic mutations impacting a gene encoding a serine/threonine kinase ATM (Ataxia Telangiectasia Mutated), which plays a crucial role in DNA repair and maintenance of genomic stability. The disorder primarily affects the nervous system, leading to a range of neurological issues, including cerebellar ataxia. …”
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Autosplenectomy in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH) by Ethan Burns, Kartik Anand, Gonzalo Acosta, Malcolm Irani, Betty Chung, Abhishek Maiti, Ibrahim Ibrahim, Lawrence Rice

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The evolving landscape: Role of artificial intelligence in cancer detection by Praveen Kumar, Sakshi V. Izankar, Induni N. Weerarathna, David Raymond, Prateek Verma

“…Furthermore, it explained the indispensable role of pathology and histopathology in cancer diagnosis, emphasizing AI's potential to augment traditional methods and improve diagnostic precision. Genomics and personalized medicine were explored as integral components of cancer detection, illustrating how AI facilitates tailored treatment strategies by analyzing vast genomic datasets. …”
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Cryo-EM structure and evolutionary history of the conjugation surface exclusion protein TraT by Chloe Seddon, Sophia David, Joshua L. C. Wong, Naito Ishimoto, Shan He, Jonathan Bradshaw, Wen Wen Low, Gad Frankel, Konstantinos Beis

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Decoding vascular aging: implications for atherosclerosis progression and clinical intervention by Silumbwe Ceaser Wankumbu, Xiao-Man Ji, Ming Xu

“…In the review, we highlighted five altered vascular mechanisms in cardiovascular models: genomic instability, neurohormonal deregulation, epigenetics, protein regulation, and the gut microbiome. …”
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A sequencing-based method for quantifying gene-deletion mutants of bacteria in the intracellular environment by Xiao Fei, Xiao Fei, Zengzhi Yuan, Zengzhi Yuan, Sandra Marina Wellner, Yibing Ma, John Elmerdahl Olsen

“…Based on standardized Illumina short-read sequencing of genomic DNA, the method eliminates the need for specific selective markers on each deletion mutant. …”
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