Islands of genomic stability in the face of genetically unstable metastatic cancer. by Kirsten Bowland, Jiaying Lai, Alyza Skaist, Yan Zhang, Selina Shiqing K Teh, Nicholas J Roberts, Elizabeth Thompson, Sarah J Wheelan, Ralph H Hruban, Rachel Karchin, Matthew H Bailey, Christine A Iacobuzio-Donahue, James R Eshleman

“…<h4>Methods</h4>Whole genome sequencing was performed on five rapid autopsy cases of patient-matched primary tumor, normal and metastatic tissue from pancreatic ductal adenocarcinoma decedents. …”
Get full text

The Complete Chloroplast Genome of Erythrina variegata L. (Papilionoideae, Fabaceae) by Nguyen Nhat Nam, Nguyen Ngoc Trai, Nguyen Phuong Thuy, Le Quoc Duy, Pham Nguyen Tuong Van, Tan Tai Nguyen, Hoang Dang Khoa Do

Subjects: “…comparative genomics…”
Get full text

Diversity and distribution of mobile genetic elements in marine invertebrates genomes by M. V. Puzakov, L. V. Puzakova, I. K. Zakharov

Subjects: Get full text

Application of reproductive technologies to the improvement of dairy cattle genomic selection by N. S. Yudin, K. I. Lukyanov, M. I. Voevoda, N. A. Kolchanov

Subjects: Get full text

Chromosome-level and haplotype-resolved genome assembly of Bougainvillea glabra by Lan Lan, Haiyan Li, Shisong Xu, Yueting Xu, Qingyun Leng, Linbi Zhang, Linqiao Wu, Junmei Yin, Zhiqiang Wu, Junhai Niu

“…In this study, based on PacBio and Hi-C sequencing data, we presented the haplotype-resolved, and chromosome-level assembled genomes for B. glabra (2n = 34). We obtained two haplotypes with genome size of 2,855,692,602 bp and 2,889,511,499 bp, N50 of 165 Mbp and 167 Mbp, and both anchored to 17 chromosomes with anchor ratio of 97.07% and 97.55%, respectively. …”
Get full text

Nanopore-based random genomic sampling for intraoperative molecular diagnosis by Francesco E. Emiliani, Abdol Aziz Ould Ismail, Edward G. Hughes, Gregory J. Tsongalis, George J. Zanazzi, Chun-Chieh Lin

“…Genome Medicine…”
Get full text

Chromosome level genome assembly of ‘Wanfeng’ almond (Prunus dulcis) by Dongdong Zhang, Zhenfan Yu, Xingyue Liu, Yong Li, Bin Zeng, Lirong Wang

“…Abstract We assembled a chromosome-level genome of Chinese native ‘Wanfeng’ almond, with a size of 288.53 Mb and a contig N50 of 30.48 Mb. …”
Get full text

Whole genome sequencing in early onset advanced heart failure by Erik Linnér, Tomasz Czuba, Olof Gidlöf, Jakob Lundgren, Entela Bollano, Maria Hellberg, Selvi Celik, Neha Pimpalwar, Philipp Rentzsch, Molly Martorella, Anders Gummesson, Olle Melander, Sebastian Albinsson, Göran Dellgren, Jan Borén, Anders Jeppsson, R. Thomas Lumbers, Sonia Shah, Johan Nilsson, Pradeep Natarajan, Tuuli Lappalainen, Malin Levin, Hans Ehrencrona, J. Gustav Smith

Subjects: Get full text

Comparative Analysis of Predicted Gene Expression among Crenarchaeal Genomes by Shibsankar Das, Brajadulal Chottopadhyay, Satyabrata Sahoo

“…Genomics & Informatics…”
Get full text

Genomic characterization of chronic lymphocytic leukemia in patients of African ancestry by Cecilia Bonolo de Campos, Chantal E. McCabe, Laura A. Bruins, Daniel R. O’Brien, Sochilt Brown, Renee C. Tschumper, Cristine Allmer, Yuan Xiao Zhu, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Huihuang Yan, James R. Cerhan, John N. Allan, Richard R. Furman, J. Brice Weinberg, Danielle M. Brander, Diane F. Jelinek, Marta Chesi, Susan L. Slager, Esteban Braggio

“…In summary, these results suggest that genomic instability and NF-kB activation is more prevalent in AA CLL than EA CLL.…”
Get full text

Genomic Characterization of Radiation-Induced Intracranial Undifferentiated Pleomorphic Sarcoma by Christopher S. Hong, Edwin Partovi, James Clune, Anita Huttner, Henry S. Park, Sacit Bulent Omay

“…Further similar genomic studies of intracranial pleomorphic sarcoma are needed to develop better therapies for this rare but challenging disease entity.…”
Get full text

IDENTIFICATION OF WHOLE GENOMES OF ENDOGENOUS RETROVIRUSES IN SIBERIAN MINIATURE PIGS by R. B. Aitnazarov, N. S. Yudin, S. V. Nikitin, V. I. Ermolayev, M. I. Voevoda

“…Currently, the frequency of carriers of types A, B, and C of PERV genomes in minipigs is high. Their breeding conducted from 2005 till 2013 increased the percentage of animals free from type B retroviruses.…”
Get full text

The big challenge for livestock genomics is to make sequence data pay by Johnsson, Martin

Subjects: “…genomics, animal breeding, genomic prediction, whole-genome sequence, quantitative genetics…”
Get full text

Structural and functional divergence of homoeologous genes in allopolyploid plant genomes by A. Y. Glagoleva, O. Y. Shoeva, E. K. Khlestkina

“…Thanks to the whole genome sequencing of a wide range of angiosperm species and comparative analysis of genome structure, the sequence of events that formed the genomes of modern plant taxa was restored. …”
Get full text

Comprehensive genome-scale CRISPR knockout screening of CHO cells by Sung Wook Shin, Su Hyun Kim, Aghiles Gasselin, Gyun Min Lee, Jae Seong Lee

“…In the present study, we conducted a genome-scale pooled CRISPR knockout (KO) screening using a virus-free, recombinase-mediated cassette exchange-based platform in CHO-K1 host and CHO-K1 derived recombinant cells. …”
Get full text

Editorial: Exploring genomic instability of cancers: applications in diagnosis and treatment by Dong Zhang, Dong Zhang, Shiaw-Yih Lin, Marietta Lee

Subjects: “…genomic instability…”
Get full text

Gut Microbiome: An Intersection between Human Genome, Diet, and Epigenetics by Abdullahi Y. Muhammad, Malik Amonov, Atif A. Baig, Farrukh J. Alvi

“…Recently, the association between the human genome and the gut microbiome has been analyzed and considered a multiomic approach, and extensive genome-wide association studies were conducted to further understand the complex relationship.…”
Get full text

Immune and genomic biomarkers of immunotherapy response in cancer of unknown primary by Madhu Singh, Linda Mileshkin, Penelope Schofield, Bo Gao, Gary Richardson, Andrew Pattison, Rodney J Hicks, Niko Thio, Mark Warren, Colin Wood, Stephen B Fox, Anna DeFazio, Andrew Fellowes, Christopher Steer, David Bowtell, Nicholas Wilcken, Tharani Sivakumaran, Atara Posner, Dariush Etemadmoghadam, Krista Fisher, Samantha Webb, Christos S Karapetis, Ian M Collins, Narayan Karanth, Owen W J Prall, Richard William Tothill

“…We therefore assessed immune and genomic biomarkers as well as predicted TOO in patients with CUP, including a subset treated with ICIs.Methods Patients with CUP were subject to gene-expression profiling (GEP) and DNA panel sequencing. …”
Get full text

Post-genomic approaches to understanding interactions between fungi and their environment by R.P. de Vries, I. Benoit, G. Doehlemann, T. Kobayashi, J.K. Magnuson, E.A. Panisk, S.E. Baker, M.-H. Lebrun

Subjects: “…(POST- )GENOMICS…”
Get full text

ICGenomics: A PROGRAM COMPLEX FOR ANALYSIS OF SYMBOL SEQUENCES IN GENOMICS by Y. L. Orlov, A. O. Bragin, I. V. Medvedeva, K. V. Gunbin, P. S. Demenkov, O. V. Vishnevsky, V. G. Levitsky, D. Y. Oshchepkov, N. L. Podkolodnyy, D. A. Afonnikov, I. Grosse, N. A. Kolchanov

Subjects: “…genomics…”
Get full text