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2281
DNA Methylation Is Involved in the Expression of miR-142-3p in Fibroblasts and Induced Pluripotent Stem Cells
Published 2014-01-01“…CpG motifs were found in the 5′ genomic region of the miR-142-3p; they were highly methylated in fibroblasts, but not in undifferentiated induced pluripotent stem cells. …”
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2282
Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy
Published 2023-01-01“…Tracking the landscape of genomic alterations detected in ctDNA may reveal the clonal architecture of the metastatic cascade and thus improve our understanding of the molecular wiring of therapeutic responses. …”
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2283
Novel PITX2 Mutations including a Mutation Causing an Unusual Ophthalmic Phenotype of Axenfeld-Rieger Syndrome
Published 2019-01-01“…The ocular manifestations of both eyes of each patient were recorded. Genomic DNA was prepared from venous leukocytes. All coding exons of PITX2 and FOXC1 were amplified by polymerase chain reaction (PCR) from genomic DNA and subjected to direct DNA sequencing. …”
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2284
Wheat landraces as sources of high grain quality and nutritional properties
Published 2024-01-01“…Mineral composition in the grain of the studied landraces was analyzed at the Kurchatov Genomic Center, Novosibirsk, using atomic absorption spectrometry techniques.Results. …”
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2285
Potato spindle tuber viroid
Published 2021-06-01“…This association between the small segments of viroid genomic RNAs complementary to the untranslated regions of cellular mRNAs and disease symptoms provides a way for new resistant cultivars to be developed by genetic editing. …”
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2286
Environmental Surveillance for SARS-CoV-2 in Two Restaurants from a Mid-scale City that Followed U.S. CDC Reopening Guidance
Published 2021-12-01“…SARS-CoV-2 genomic RNA was not detected in any of the air samples. …”
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2287
Prioritization of biological processes based on the reconstruction and analysis of associative gene networks describing the response of plants to adverse environmental factors
Published 2021-09-01“…This is largely due to the development of technologies to solve problems in marker-oriented and genomic selection, which requires knowledge of the molecular genetic mechanisms underlying the formation of agriculturally valuable traits. …”
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2288
Intratumor heterogeneity of HPV integration in HPV-associated head and neck cancer
Published 2025-01-01“…Whole-genome sequencing of 51 tumors revealed intratumor heterogeneity of HPV integration, with 44% of breakpoints subclonal, and a biased distribution of integration breakpoints across the HPV genome. …”
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2289
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2290
Cancer, Senescence, and Aging: Translation from Basic Research to Clinics
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2291
Des graines, des fibres et des bobines
Published 2019-06-01“…This limited chronological framework differs from other studies devoted to the history of Gossypium sp. which explore their genomic evolution or the diffusion of textile techniques over several centuries. …”
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2292
Raise and characterization of a bread wheat hybrid line (Tulaykovskaya 10 × Saratovskaya 29) with chromosome 6Agi2 introgressed from Thinopyrum intermedium
Published 2021-12-01“…Chromosome 6Agi2 was identified by PCR with chromosome-specific primers and by genomic in situ hybridization (GISH). According to molecular data, 6Agi2 was transmitted to nearly half of the plants tested in the F2 and F3 generations. …”
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2293
Clinicopathological study and molecular subtyping of muscle-invasive bladder cancer (MIBC) using dual immunohistochemical (IHC) markers
Published 2025-01-01“…As molecular subtyping is complex, surrogate immunohistochemical (IHC) markers have been used to determine the molecular subtypes with good correlation to genomic profiling. Methods We analysed the clinicopathological features of 66 cases of MIBCs received over a 5-year study period. …”
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2294
Towards climate-resilient conservation: Integrating genetics and environmental factors in determining adaptive units of a xeric shrub
Published 2025-01-01“…The study emphasizes the necessity of incorporating adaptive diversity in conservation strategies and recommends establishing MUs that align with adaptive genotypes and climatic conditions. Integrating genomic insights into breeding programs can further enhance the resilience and sustainable management of this vulnerable species.…”
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2295
Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024
Published 2025-02-01“…Genome sequence analysis was performed with CLC Genomics Workbench, and genotyping and sequence alignment were carried out using the Nextclade platform. …”
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2296
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2297
How to convert a 3D printer to a personal automated liquid handler for life science workflows
Published 2025-02-01“…The PALH system was evaluated through common life science assays, including preparing real-time PCR samples, end-point PCR with novel pipet-based downstream purification, and genomic DNA extraction from peripheral whole blood. …”
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2298
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2299
Refining prognostic assessment of diffuse large B-cell lymphoma: insights from multi-omics and single-cell analysis unveil SRM as a key target for regulating immunotherapy
Published 2025-01-01“…Mechanisms underlying adverse prognosis in the high-risk DLBCLs were investigated through transcriptomic (n = 3,229), genomic (n = 576), and scRNA-seq (n = 20) analyses. …”
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2300
CGH, cDNA and Tissue Microarray Analyses Implicate FGFR2 Amplification in a Small Subset of Breast Tumors
Published 2001-01-01“…Multiple regions of the genome are often amplified during breast cancer development and progression, as evidenced in a number of published studies by comparative genomic hybridization (CGH). …”
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