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Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders
Published 2016-01-01Get full text
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The Effect of Continuous Selection in KiwiCross<sup>®</sup> Composite Breed on Breed Ancestry and Productivity Performance
Published 2025-01-01“…We hypothesized that certain genomic regions from Holstein-Friesian or Jersey breeds were preserved due to artificial selection based on PR. …”
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Unravelling single-cell DNA replication timing dynamics using machine learning reveals heterogeneity in cancer progression
Published 2025-02-01“…Abstract Genomic heterogeneity has largely been overlooked in single-cell replication timing (scRT) studies. …”
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Heterosis: current advances in the search for molecular mechanisms
Published 2016-12-01“…To date, differences in genome organization, gene expression and epigenetic status have been found between hybrids and their parents. …”
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Angelman-Like Syndrome: A Genetic Approach to Diagnosis with Illustrative Cases
Published 2016-01-01“…With the advancement of genomic technology like array comparative genomic hybridization and next generation sequencing methods, it is found that some patients of these test negative Angelman-like Syndromes actually have alternative diagnoses. …”
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Peculiar Evolutionary History of miR390-Guided TAS3-Like Genes in Land Plants
Published 2013-01-01“…Importantly, cloning and sequencing of Marchantia polymorpha genomic DNA showed miR390 and TAS3-like sequences which were also found among genomic reads of M. polymorpha at NCBI database. …”
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Tracking the genetic diversity of SARS-CoV-2 variants in Nicaragua throughout the COVID-19 pandemic
Published 2025-02-01“…This study characterizes the genomic diversity of SARS-CoV-2 in Nicaragua from March 2020 through December 2022, utilizing 1064 genomes obtained via next-generation sequencing. …”
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Development of a rapid detection technology system for noxious plants based on a novel isothermal amplification technique
Published 2025-01-01“…The entire process, from sample collection, genomic DNA preparation to reaction completion, takes approximately 35 minutes. …”
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DNA Ligase IV Prevents Replication Fork Stalling and Promotes Cellular Proliferation in Triple Negative Breast Cancer
Published 2019-01-01“…DNA damage is a hallmark of cancer, and mutation and misregulation of proteins that maintain genomic fidelity are associated with the development of multiple cancers. …”
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Pharmacogenomics Tools for Precision Public Health and Lessons for Low- and Middle-Income Countries: A Scoping Review
Published 2025-01-01“…The objective of this study was to conduct a scoping review of technological tools, examining their evolution, the predominance of high-income countries in their development, and the gaps and needs for genomic data and advances in low- and middle-income countries (LMICs). …”
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The landscape of nucleotide diversity in Drosophila melanogaster is shaped by mutation rate variation
Published 2023-04-01“…What shapes the distribution of nucleotide diversity along the genome? Attempts to answer this question have sparked debate about the roles of neutral stochastic processes and natural selection in molecular evolution. …”
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Network-assisted target identification for haploinsufficiency and homozygous profiling screens.
Published 2017-06-01“…Chemical genomic screens have recently emerged as a systematic approach to drug discovery on a genome-wide scale. …”
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