Blood-based epigenome-wide association study and prediction of alcohol consumption by Elena Bernabeu, Aleksandra D. Chybowska, Jacob K. Kresovich, Matthew Suderman, Daniel L. McCartney, Robert F. Hillary, Janie Corley, Maria Del C. Valdés-Hernández, Susana Muñoz Maniega, Mark E. Bastin, Joanna M. Wardlaw, Zongli Xu, Dale P. Sandler, Archie Campbell, Sarah E. Harris, Andrew M. McIntosh, Jack A. Taylor, Paul Yousefi, Simon R. Cox, Kathryn L. Evans, Matthew R. Robinson, Catalina A. Vallejos, Riccardo E. Marioni

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A new insight into the impact of copy number variations on cell cycle deregulation of luminal-type breast cancer by Amir Mahdi Khamaneh, Davoud Jafari-Gharabaghlou, Khalil Ansarin, Khalil Ansarin, Khalil Ansarin, Pouya Pazooki, Zahra Akbarpour, Behrooz Naghili, Behrooz Naghili, Nosratollah Zarghami, Nosratollah Zarghami

“…Structural and Numerical-Chromosomal instability initiates tumor development and is recognized as the primary driver of genetic alteration in luminal breast tumors. Genomic instability refers to the increased tendency of cancer cells to accumulate genomic alterations during cell proliferation. …”
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Rational metabolic engineering of <i>Corynebacterium glutamicum</i> to create a producer of L-valine by M. E. Sheremetieva, K. E. Anufriev, T. M. Khlebodarova, N. A. Kolchanov, A. S. Yanenko

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High throughput single cell metagenomic sequencing with semi-permeable capsules: unraveling microbial diversity at the single-cell level in sewage and fecal microbiomes by Meilee Ling, Judit Szarvas, Vaida Kurmauskaitė, Vaidotas Kiseliovas, Rapolas Žilionis, Rapolas Žilionis, Baptiste Avot, Baptiste Avot, Patrick Munk, Frank M. Aarestrup

“…Our method involves extracting and amplifying single bacterial DNA within individual SPCs, followed by combinatorial split-and-pool single-amplified genome (SAG) barcoding and short-read sequencing. …”
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Geo-behavioural predictors of diagnosed hypertension in Igbo Ora Area, Oyo State, Nigeria by Olalekan J. Taiwo, Joshua O. Akinyemi, Ayodeji Adebayo, Oluwafemi A. Popoola, Rufus O. Akinyemi, Onoja M. Akpa, Paul Olowoyo, Akinkunmi P. Okekunle, Ezinne O. Uvere, Omotolani Titilayo Ajala, Chukwuemeka Nwimo, Olayinka J. Adebajo, Adewale E. Ayodele, Ayodeji Salami, Oyedunni S. Arulogun, Olanrewaju Olaniyan, Richard W. Walker, Carolyn Jenkins, Bruce Ovbiagele, Mayowa Owolabi

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PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival by Chenxiao Yu, Marco Tigano, Erin L Seifert

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Detection of genetic relations between species in the genus Prunus L. when using them in breeding of stone fruit crops by G. V. Eremin

“…This effect is manifested by hybrids between the species of the subgenus Prunophora, and the species of the subgenus Amygdalus;-    the fourth level: no hybrids are produced.Genomic morphological markers were also used in genomic analysis. …”
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Maximising informativeness for target capture-based phylogenomics in Erica (Ericaceae) by Seth D. Musker, Nicolai M. Nürk, Michael D. Pirie

“…Plant phylogenetics has been revolutionised in the genomic era, with target capture acting as the primary workhorse of most recent research in the new field of phylogenomics. …”
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National Thalassemia Registry: a 30 year journey of implementing carrier screening in Singapore by Stella Zhang, Guek Peng Tan, Soh Lan Peh, Swee Lim Ang, Sylvia Kam, Weng Khong Lim, Teck Wah Ting, Angeline Lai, Ee Shien Tan, Saumya Shekhar Jamuar, Hai Yang Law, Ivy Ng

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Gut-Lung Axis in COVID-19 by Imane Allali, Youssef Bakri, Saaïd Amzazi, Hassan Ghazal

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Production of subtilisin proteases in bacteria and yeast by A. S. Rozanov, S. V. Shekhovtsov, N. V. Bogacheva, E. G. Pershina, A. V. Ryapolova, D. S. Bytyak, S. E. Peltek

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Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

“…The correct deployment of genetic programs for development and differentiation relies on finely coordinated regulation of specific gene sets. Genomic regulatory elements play an exceptional role in this process. …”
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Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat by François Brial, Aurélie Le Lay, Claude Rouch, Edouard Henrion, Mathieu Bourgey, Guillaume Bourque, Mark Lathrop, Christophe Magnan, Dominique Gauguier

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GBS-DP: a bioinformatics pipeline for processing data coming from genotyping by sequencing by A. Y. Pronozin, E. A. Salina, D. A. Afonnikov

“…It has been applied to genetic mapping, molecular marker discovery, genomic selection, genetic diversity studies, variety identification, conservation biology and evolutio nary studies. …”
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Human-Specific Endogenous Retroviruses by Anton Buzdin

“…This review focuses on a small family of human-specific genomic repetitive elements, presented by 134 members that shaped ~330 kb of the human DNA. …”
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Molecular-genetic pathways of hepatitis C virus regulation of the expression of cellular factors PREB and PLA2G4C, which play an important role in virus replication by E. L. Mishchenko, A. A. Makarova, E. A. Antropova, A. S. Venzel, T. V. Ivanisenko, P. S. Demenkov, V. A. Ivanisenko

“…However, rapid mutation processes in the viral genome and acquisition of drug resistance to the existing drugs remain the main obstacles to fighting HCV. …”
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Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation by Jeeho Kim, Young Jin Jeon, In-Youb Chang, Jung-Hee Lee, Ho Jin You

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Splicing accuracy varies across human introns, tissues, age and disease by S. García-Ruiz, D. Zhang, E. K. Gustavsson, G. Rocamora-Perez, M. Grant-Peters, A. Fairbrother-Browne, R. H. Reynolds, J. W. Brenton, A. L. Gil-Martínez, Z. Chen, D. C. Rio, J. A. Botia, S. Guelfi, L. Collado-Torres, M. Ryten

“…We find support for the latter by observing a genome-wide increase in splicing inaccuracies in samples affected with Alzheimer’s disease as compared to neurologically normal individuals. …”
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A software module to assess the metabolic potential of mutant strains of the bacterium <i>Corynebacterium glutamicum</i> by F. V. Kazantsev, M. F. Trofimova, T. M. Khlebodarova, Yu. G. Matushkin, S. A. Lashin

“…There are already 5 whole-genome flux balance models for it, which can be used for me­tabolism research and optimization tasks. …”
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DArTseq-based silicoDArT and SNP markers reveal the genetic diversity and population structure of Kenyan cashew (Anacardium occidentale L.) landraces. by Dennis Wamalabe Mukhebi, Pauline Wambui Gachanja, Diana Jepkoech Karan, Brenda Muthoni Kamau, Pauline Wangeci King'ori, Bicko Steve Juma, Wilton Mwema Mbinda

“…Understanding cashew genomics through the application of SilicoDArT and SNP markers is crucial for advancing cashew genomic breeding programs aimed at improving yield and nut quality, and enhancing resistance or tolerance to biotic and abiotic stresses. …”
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