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When Long Noncoding RNAs Meet Genome Editing in Pluripotent Stem Cells
Published 2017-01-01“…Here, we summarize recent advancements in dissecting the roles of lncRNAs with genome editing technologies in PSCs and highlight potential genome editing tools useful for examining the functions of lncRNAs in PSCs.…”
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Genome Editing: A Promising Approach for Achieving Abiotic Stress Tolerance in Plants
Published 2022-01-01“…It also highlights the emerging potential of genome editing for developing abiotic stress-resilient crops.…”
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CRISPR/Cas genome editing for cotton precision breeding: mechanisms, advances, and prospects
Published 2025-02-01“…The constantly increasing demand needs a significant rise in cotton production. Genome editing technology, specifically with clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) tools, has opened new possibilities for trait development in cotton. …”
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Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy
Published 2018-01-01“…Furthermore, we discuss recent advances in the field of genome editing and stem cell technologies, which together enable precise and personalized therapies for patients. …”
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Efficient genome editing in dicot plants using calreticulin promoter-driven CRISPR/Cas system
Published 2025-02-01Get full text
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Genome Editing as a Vehicle to Drive Successful Chimeric Antigen Receptor T Cell Therapies to the Clinic
Published 2021-12-01“…Recent efforts have been directed toward incorporating genome editing technologies to address these challenges and develop potent CAR T cell therapies for a diverse array of haematopoietic cancers. …”
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Engineered CRISPR-Cas9 for Streptomyces sp. genome editing to improve specialized metabolite production
Published 2025-01-01“…Abstract The CRISPR-Cas9 system has frequently been used for genome editing in Streptomyces; however, cytotoxicity, caused by off-target cleavage, limits its application. …”
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The study of the regulatory region of the Drosophila melanogaster Notch gene by new methods of directed genome editing
Published 2019-03-01“…The development of new methods for directed genome editing made it possible to create a system for introducing directed changes into the regulatory zone of the gene. …”
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CRISPR/Cas9-Based Protocol for Precise Genome Editing in Induced Pluripotent Stem Cells
Published 2024-12-01“…The advent of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-based genome editing has marked a significant advancement in genetic engineering technology. …”
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Robust genome editing activity and the applications of enhanced miniature CRISPR-Cas12f1
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Huntington’s disease modeling on HEK293 cell line
Published 2017-12-01Subjects: Get full text
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Genes for editing to improve economic traits in aquaculture fish species
Published 2025-01-01Subjects: Get full text
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Robust and inducible genome editing via an all-in-one prime editor in human pluripotent stem cells
Published 2024-12-01“…Abstract Prime editing (PE) allows for precise genome editing in human pluripotent stem cells (hPSCs), such as introducing single nucleotide modifications, small insertions or deletions at a specific genomic locus. …”
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In defence of South Africa’s National Health Research Ethics Council guidelines on heritable human genome editing
Published 2025-02-01Subjects: “…heritable human genome editing…”
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HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells
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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei
Published 2025-01-01“…Another potent tool is the CRISPR/Cas9 technology, which has enabled targeted genome editing with higher accuracy and specificity and greatly advanced genome engineering in Plasmodium spp. …”
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Cellular Reprogramming, Genome Editing, and Alternative CRISPR Cas9 Technologies for Precise Gene Therapy of Duchenne Muscular Dystrophy
Published 2017-01-01“…In particular, Duchenne muscular dystrophy (DMD) has been an exemplary monogenic disease model for combining these technologies to demonstrate that genome editing can correct genetic mutations in DMD patient-derived iPSCs. …”
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Successful establishment of CRISPR-based genome-edited clonal cell populations from primary cells of buffalo, goats, and sheep
Published 2023-11-01Subjects: Get full text
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CRISPR/Cas9-Mediated Editing of a <i>NODULATION SIGNALING PATHWAY 1</i> Homolog Alters the Production of Strigolactones in Sunflower Roots
Published 2025-01-01Subjects: Get full text
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