Showing 661 - 680 results of 5,161 for search '"genome"', query time: 0.07s Refine Results
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    Defective homologous recombination and genomic instability predict increased responsiveness to carbon ion radiotherapy in pancreatic cancer by Brock J. Sishc, Janapriya Saha, Elizabeth M. Alves, Lianghao Ding, Huiming Lu, Shih-Ya Wang, Katy L. Swancutt, James H. Nicholson, Angelica Facoetti, Arnold Pompos, Mario Ciocca, Todd A. Aguilera, Michael D. Story, Anthony J. Davis

    Published 2025-01-01
    “…Increased radiosensitivity was linked to impaired DNA double-strand break (DSB) repair, particularly in cell lines with deficiencies in the homologous recombination (HR) repair pathway and/or elevated genomic instability from replication stress. Furthermore, pretreatment with the HR inhibitor B02 significantly enhanced CIRT sensitivity in a radioresistant PDAC cell line when irradiated in the spread-out Bragg peak but not at the entry position of the beam. …”
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    Prioritization of causal genes from genome-wide association studies by Bayesian data integration across loci. by Zeinab Mousavi, Marios Arvanitis, ThuyVy Duong, Jennifer A Brody, Alexis Battle, Nona Sotoodehnia, Ali Shojaie, Dan E Arking, Joel S Bader

    Published 2025-01-01
    “…<h4>Motivation</h4>Genome-wide association studies (GWAS) have identified genetic variants, usually single-nucleotide polymorphisms (SNPs), associated with human traits, including disease and disease risk. …”
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    Genomic characteristics and molecular epidemiology of MRSA from medical centers in Mexico: Results from the Invifar network. by Gabriela Echaniz-Avilés, Luis Ángel Núñez-García, Eduardo Rodríguez-Noriega, Consuelo Velázquez-Acosta, Luis Esaú López-Jácome, Eduardo López-Gutiérrez, Talia Pérez-Vicelis, Cristina Torres-Báez, Ulises Garza-Ramos, Nadia Rodríguez-Medina, Juan Manuel Barajas-Magallón, Rosario Vázquez-Larios, Aldo Rafael Silva-Gamiño, Rafael Franco-Cendejas, Adolfo Gómez-Quiroz, Elvira Garza-González

    Published 2025-01-01
    “…<h4>Introduction</h4>The methicillin-resistant Staphylococcus aureus (MRSA) genome varies by geographical location. This study aims to determine the genomic characteristics of MRSA using whole-genome sequencing (WGS) data from medical centers in Mexico and to explore the associations between antimicrobial resistance genes and virulence factors.…”
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    Clinical isolates of Candida auris with enhanced adherence and biofilm formation due to genomic amplification of ALS4. by Jian Bing, Zhangyue Guan, Tianhong Zheng, Zhijie Zhang, Shuru Fan, Craig L Ennis, Clarissa J Nobile, Guanghua Huang

    Published 2023-03-01
    “…Global transcriptional profiling and quantitative real-time PCR assays indicated that genomic amplification of ALS4 results in a dramatic increase in overall levels of transcription. …”
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    Prevalent integration of genomic repetitive and regulatory elements and donor sequences at CRISPR-Cas9-induced breaks by Chongwei Bi, Baolei Yuan, Yingzi Zhang, Mengge Wang, Yeteng Tian, Mo Li

    Published 2025-01-01
    “…RE frequencies and 3D genome organization analysis suggest LgIns originate from randomly acquired genomic fragments by DNA repair mechanisms. …”
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    Complete Whole Genome Sequence of Vibrio parahaemolyticus RP0132 Strain Isolated from Shrimp in Malaysia by Ke-Yan Loo, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Kah-Ooi Chua, Priyia Pusparajah, Learn-Han Lee, Vengadesh Letchumanan

    Published 2023-12-01
    “…Therefore, we report the genome sequence of V. parahaemolyticus RP0132 isolated from shrimp to gain insight into its antimicrobial resistance traits and potential resistance mechanisms. …”
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