Geo-behavioural predictors of diagnosed hypertension in Igbo Ora Area, Oyo State, Nigeria by Olalekan J. Taiwo, Joshua O. Akinyemi, Ayodeji Adebayo, Oluwafemi A. Popoola, Rufus O. Akinyemi, Onoja M. Akpa, Paul Olowoyo, Akinkunmi P. Okekunle, Ezinne O. Uvere, Omotolani Titilayo Ajala, Chukwuemeka Nwimo, Olayinka J. Adebajo, Adewale E. Ayodele, Ayodeji Salami, Oyedunni S. Arulogun, Olanrewaju Olaniyan, Richard W. Walker, Carolyn Jenkins, Bruce Ovbiagele, Mayowa Owolabi

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A guide to selecting high-performing antibodies for Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) for use in Western Blot, immunoprecipi... by Carl Laflamme, Kathleen Southern, Riham Ayoubi, Maryam Fotouhi, Charles Alende

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Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat by François Brial, Aurélie Le Lay, Claude Rouch, Edouard Henrion, Mathieu Bourgey, Guillaume Bourque, Mark Lathrop, Christophe Magnan, Dominique Gauguier

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Unravelling single-cell DNA replication timing dynamics using machine learning reveals heterogeneity in cancer progression by Joseph M. Josephides, Chun-Long Chen

“…Abstract Genomic heterogeneity has largely been overlooked in single-cell replication timing (scRT) studies. …”
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Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation by Jeeho Kim, Young Jin Jeon, In-Youb Chang, Jung-Hee Lee, Ho Jin You

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Improved growth performance, food efficiency, and lysine availability in growing rats fed with lysine-biofortified rice by Qing-Qing Yang, Pui Kit Suen, Chang-Quan Zhang, Wan Sheung Mak, Ming-Hong Gu, Qiao-Quan Liu, Samuel Sai-Ming Sun

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Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment. by Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C deCarvalho

“…Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). …”
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ADAM-multi: software to simulate complex breeding programs for animals and plants with different ploidy levels and generalized genotypic effect models to account for multiple allel... by Thinh Tuan Chu, Thinh Tuan Chu, Just Jensen

“…Along with the description of the updated simulation model in ADAM-Multi, this paper shows two small-scale studies that investigate the effects of multi-allelic versus bi-allelic assumptions in simulation and the use of different prediction models in a single-population breeding program for potatoes. We found that genomic models using dense bi-allelic markers could effectively predicted breeding values of individuals in a well-structure population despite the presence of multi-allelic QTL. …”
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In vitro micropropagation protocols for two endangered Dianthus species - via in vitro culture for conservation and recultivation purposes by Dóra Farkas, Judit Csabai, Angéla Kolesnyk, Pál Szarvas, Judit Dobránszki

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Porcine sperm bind to an oviduct glycan coupled to glass surfaces as a model of sperm interaction with the oviduct by Sandra Soto-Heras, Larissa J. Volz, Nicolai Bovin, David J. Miller

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Genetic parameters and parental and early-life effects of boar semen traits by Pedro Sá, Rodrigo M. Godinho, Marta Gòdia, Claudia A. Sevillano, Barbara Harlizius, Ole Madsen, Henk Bovenhuis

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Multi-locus CRISPRi targeting with a single truncated guide RNA by Molly M. Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J. Cruz, Yanjing V. Liu, Nauman Javed, Salvador Casaní-Galdón, Jason D. Buenrostro, Charles B. Epstein, Eugenio Mattei, John G. Doench, Bradley E. Bernstein, Noam Shoresh, Fadi J. Najm

“…Abstract A critical goal in functional genomics is evaluating which non-coding elements contribute to gene expression, cellular function, and disease. …”
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The effects of Thymus capitatus essential oil topical application on milk quality: a systems biology approach by Ralph Nehme, Chiara Gini, Elise Vanbergue, Sergine Even, Filippo Biscarini, Sonia Andrés, Lucie Rault, Faustine Noel, Valerie Hardit, Said Bouhallab, David M. Pereira, Riadh Ksouri, Philippe Roussel, Secundino López, Paola Cremonesi, Bianca Castiglioni, Donatella Caruso, Fiorenza Faré, Manuela Fontana, Fabrizio Ceciliani, Latifa Abdennebi-Najar

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Chronic wounds and adaptive Pseudomonas aeruginosa: A phenotypic and genotypic characterization by Kasandra Buchholtz, Rie Jønsson, Rasmus L. Marvig, Biljana Mojsoska, Karen Angeliki Krogfelt

“…This was performed using genomic and phenotypic approaches to understand the survival and persistence of Pseudomonas strains. …”
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Overcoming immunotherapy resistance in gastric cancer: insights into mechanisms and emerging strategies by Dingtian Luo, Jing Zhou, Shuiliang Ruan, Binzhong Zhang, Huali Zhu, Yangming Que, Shijie Ying, Xiaowen Li, Yuanmin Hu, Zhengwei Song

“…We also discuss emerging strategies to overcome resistance, including combination therapies, novel immunotherapeutic approaches, and personalized treatment strategies based on tumor genomics and the immune microenvironment. By highlighting these key areas, this review aims to inform future research directions and clinical practice, ultimately improving outcomes for GC patients undergoing immunotherapy.…”
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The microbiome of Total Suspended Particles and its influence on the respiratory microbiome of healthy office workers by Giulia Solazzo, Sabrina Rovelli, Simona Iodice, Matthew Chung, Michael Frimpong, Valentina Bollati, Luca Ferrari, Elodie Ghedin

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The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD by Magdalena Paplińska-Goryca, Paulina Misiukiewicz-Stępień, Monika Wróbel, Katarzyna Mycroft-Rzeszotarska, Dorota Adamska, Julia Rachowka, Milena Królikowska, Krzysztof Goryca, Rafał Krenke

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Hairy transcriptional repression targets and cofactor recruitment in Drosophila. by Daniella Bianchi-Frias, Amir Orian, Jeffrey J Delrow, Julio Vazquez, Alicia E Rosales-Nieves, Susan M Parkhurst

“…This approach identified 40 novel genomic targets for Hairy in Kc cells, as well as 155 loci recruiting Groucho, 107 loci recruiting dSir2, and wide genomic binding of dCtBP to 496 loci. …”
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An Effective and Safe Maize Seed Chipping Protocol Using Clipping Pliers With Applications in Small-Scale Genotyping and Marker-Assisted Breeding by Brian Zebosi, John Ssengo, Lander Geadelmann, Erica Unger-Wallace, Erik Vollbrecht

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Relationship between Abnormal Lipid Metabolism and Gallstone Formation by Xiang Li, Xiaodan Yin, Jun Xu, Lei Geng, Zhengtao Liu

“…This study aimed to determine the role of lipid metabolism in the pathogenesis of gallstones and provide insights for future studies using previous research in genomics, metabolomics, transcriptomics, and other fields.…”
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