PneumoniaCheck, a novel aerosol collection device, permits capture of airborne Mycobacterium tuberculosis and characterisation of the cough aeromicrobiome in people with tuberculos... by Tinaye L. Chiyaka, Georgina R. Nyawo, Charissa C. Naidoo, Suventha Moodley, Jose C. Clemente, Stephanus T. Malherbe, Robin M. Warren, David N. Ku, Leopoldo N. Segal, Grant Theron

Get full text

Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2 by Siyao Li, Mingdan You, Chengjie Chen, Jingqi Fu, Yuanyuan Xu, Jingbo Pi, Yi Wang

Get full text

Evaluation of wheat products with high flavonoid content: justification of importance of marker-assisted development and production of flavonoid-rich wheat cultivars by E. K. Khlestkina, N. I. Usenko, E. I. Gordeeva, O. I. Stabrovskaya, I. B. Sharfunova, Y. S. Otmakhova

“…These two wheat lines have almost similar genomes with the exception of a small part of chromosome 2A, which contains the Pp3/TaMyc1 gene regulating anthocyanin biosynthesis. …”
Get full text

Enhancing surveillance for dengue fever in Oyo State, Nigeria – a one health approach by Olawale Sunday Animasaun, Joseph Ojonugwa Shaibu, Busayo Kayode Akomolafe, Olamide Priscilla Animasaun, Piring’ar Mercy Niyang, Olukemi Titilope Olugbade, Akinfemi Oyewumi Akinyode, Ibukun Akinsola Omisakin, Adedapo Olufemi Adeogun, Rosemary Ajuma Audu

Get full text

The impact of trauma and how to intervene: a narrative review of psychotraumatology over the past 15 years by Miranda Olff, Irma Hein, Ananda B. Amstadter, Cherie Armour, Marianne Skogbrott Birkeland, Eric Bui, Marylene Cloitre, Anke Ehlers, Julian D. Ford, Talya Greene, Maj Hansen, Nathaniel G. Harnett, Debra Kaminer, Catrin Lewis, Alessandra Minelli, Barbara Niles, Nicole R. Nugent, Neil Roberts, Matthew Price, Anthony N. Reffi, Soraya Seedat, Antonia V. Seligowski, Anka A. Vujanovic

Get full text

Investigation of metabolic features of glioblastoma tissue and the peritumoral environment using targeted metabolomics screening by LC-MS/MS and gene network analysis by N. V. Basov, A. V. Adamovskaya, A. D. Rogachev, E. V. Gaisler, P. S. Demenkov, T. V. Ivanisenko, A. S. Venzel, S. V. Mishinov, V. V. Stupak, S. V. Cheresiz, O. S. Oleshko, E. A. Butikova, A. E. Osechkova, Yu. S. Sotnikova, Y. V. Patrushev, A. S. Pozdnyakov, I. N. Lavrik, V. A. Ivanisenko, A. G. Pokrovsky

Get full text

Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples by Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Maxim Sorokin, Vladimir Lyadov, Vladimir Lyadov, Vladimir Lyadov, Maria Suntsova, Marat Garipov, Anna Semenova, Natalia Popova, Egor Guguchkin, Rustam Heydarov, Marianna Zolotovskaia, Xiaowen Zhao, Qing Yan, Ye Wang, Evgeny Karpulevich, Anton Buzdin, Anton Buzdin, Anton Buzdin, Anton Buzdin

Get full text

Metabolite Profiling and Association Analysis of Leaf Tipburn in Heat-Tolerant Bunching Onion Varieties by Tetsuya Nakajima, Reina Yamamoto, Kanako Matsuse, Masato Fuji, Koei Fujii, Sho Hirata, Mostafa Abdelrahman, Muneo Sato, Masami Yokota Hirai, Masayoshi Shigyo

Get full text

Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production by Michelle A.E. Brouwer, Zara Karami, Samuel T. Keating, Hedwig Vrijmoeth, Heidi L.M. Lemmers, Helga Dijkstra, Frank L. van de Veerdonk, Mihaela Lupse, Hadewych J.M. ter Hofstede, Mihai G. Netea, Leo A.B. Joosten

Get full text

Small RNA CjNC110 regulates the activated methyl cycle to enable optimal chicken colonization by Campylobacter jejuni by Brandon Ruddell, Alan Hassall, Orhan Sahin, Paul J. Plummer, Qijing Zhang, Amanda J. Kreuder

“…Depending on the strain examined and accessory genomic content present, conserved regulatory actions might be masked, thus investigation in multiple strains may be warranted.…”
Get full text

Pharmacogenomic profiling of variants affecting efficacy and toxicity of anti-infective medicines in a south Asian population from Sri Lanka by Priyanga Ranasinghe, Hajanthy Jeyapragasam, Nirmala Sirisena, D. P. Bhagya Hendalage, Vajira H. W. Dissanayake

“…Sri Lankan genetic data were sourced from an anonymized database of 670 Sri Lankans maintained by the Centre for Genetics and Genomics, Faculty of Medicine, University of Colombo. …”
Get full text

Folic acid alleviates the negative effects of dexamethasone induced stress on production performance in Hyline Brown laying hens by Xi Sun, Chaohui Wang, Sijing Li, Xiaoying Liu, Yun Li, Yumeng Wang, Yuxin Niu, Zhouzheng Ren, Xin Yang, Xiaojun Yang, Yanli Liu

“…Kyoto Encyclopedia of Genes and Genomes enrichment from the transcriptome and metabolomics showed that the reduced production performance may be due to the disturbance of oocyte production, calcium metabolism, and oxidative stress. …”
Get full text

Telomere Length Is Associated With Adverse Atrial Remodeling in Patients With Atrial Fibrillation by Kabita Pradhan, Balram Neupane, Paul Niehues, Martin Kirschner, Fabian Beier, Chao‐Chung Kuo, Erika Anneliese Hilbold, Christian Bär, Oana‐Maria Thoma, Maximilian Waldner, Margherita Vieri, Tim H. Brümmendorf, Vithurithra Tharmapalan, Wolfgang Wagner, Michael Kleines, Mahdi Emrani, Matthias Daniel Zink, Andreas Napp, Nikolaus Marx, Michael Gramlich

Get full text

Adjuvant Autologous Melanoma Vaccine for Macroscopic Stage III Disease: Survival, Biomarkers, and Improved Response to CTLA-4 Blockade by Michal Lotem, Sharon Merims, Stephen Frank, Tamar Hamburger, Aviram Nissan, Luna Kadouri, Jonathan Cohen, Ravid Straussman, Galit Eisenberg, Shoshana Frankenburg, Einat Carmon, Bilal Alaiyan, Shlomo Shneibaum, Zeynep Ozge Ayyildiz, Murat Isbilen, Kerem Mert Senses, Ilan Ron, Hanna Steinberg, Yoav Smith, Eitan Shiloni, Ali Osmay Gure, Tamar Peretz

Get full text

Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

Get full text

Association of Irisin with Fat Mass, Resting Energy Expenditure, and Daily Activity in Conditions of Extreme Body Mass Index by María Pardo, Ana B. Crujeiras, María Amil, Zaida Aguera, Susana Jiménez-Murcia, Rosa Baños, Cristina Botella, Rafael de la Torre, Xavier Estivill, Ana B. Fagundo, Jose M. Fernández-Real, José C. Fernández-García, Gema Fruhbeck, Javier Gómez-Ambrosi, Roser Rodríguez, Francisco J. Tinahones, Fernando Fernández-Aranda, Felipe F. Casanueva

Get full text

Targeting NANOS1 in triple-negative breast cancer: synergistic effects of digoxin and PD-1 inhibitors in modulating the tumor immune microenvironment by Tangyi Wang, Yadian Lei, Jingwei Sun, Li Wang, Yuxin Lin, Zhijing Wu, Shoude Zhang, Chengzhu Cao, Chengzhu Cao, Chengzhu Cao, Haiyan Wang, Haiyan Wang, Haiyan Wang

“…RNA-seq analysis after target silencing by small interfering RNA (siRNA) was performed, followed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. Validation of findings was conducted through quantitative PCR and Western blot analysis.ResultsTOE inhibited TNBC cell growth, migration, and invasion, as assessed by CCK-8 and transwell assays. …”
Get full text

Diverse fox circovirus (Circovirus canine) variants circulate at high prevalence in grey wolves (Canis lupus) from the Northwest Territories, Canada by Canuti, Marta, King, Abigail V.L., Franzo, Giovanni, Cluff, H. Dean, Larsen, Lars E., Fenton, Heather, Dufour, Suzanne C., Lang, Andrew S.

“…Phylogenetic analysis of all available complete fox circovirus genomes (32 from foxes and 15 from wolves from North America and Europe) demonstrated four lineages, each including sequences from this study. …”
Get full text

شناسایی و بررسی سیلیمارین قارچ اﻧﺪوﻓﻳﺖ ﺟﺪاﺳﺎزی شده از بذر گیاه خارمریم (Silybum marianum (L) Gaert.) by هدی السادات عقیلی, حسین مرادی, محمد علی تاجیک قنبری, ولی الله قاسمی

“…سپس با نرم‌افزارCLC Genomics Workbench5.5.2 مورد تجزیه و تحلیل قرار گرفته و جدول مشخصات آنها رسم گردید. …”
Get full text

Innovative models of healthcare delivery: an umbrella review of reviews by Frances Rapport, Jeffrey Braithwaite, Yvonne Zurynski, Peter D Hibbert, Kate Churruca, Louise A Ellis, Chiara Pomare, Robyn Clay-Williams, Stephanie Best, Janet C Long, Gaston Arnolda, Bróna Nic Giolla Easpaig, Zeyad Mahmoud, Mitchell N Sarkies, Hoa Mi Nguyen, Karen Hutchinson, Gilbert Thomas Knaggs, Katherine Maka, Elizabeth E Austin, Diana Fajardo Pulido, Sarah Hatem, Natalie Roberts, Emilie Francis Auton, Genevieve Dammery, Isabelle Meulenbroeks, Ann Carrigan, Mai-Tran Nguyen

Get full text