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4521
Acorus shannai (Acoraceae), a new species from Southern China
Published 2025-01-01“…Based on morphological and plastid genomic data, this study formally describes and illustrates Acorus shannai, distributed in the Qiandongnan area of Guizhou Province and its surroundings, confirming it as a new species within the genus Acorus. …”
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4522
Alcohol consumption and allergic diseases: Mendelian randomization evidence from China
Published 2024-12-01“…Objectives This study aimed to integrate survey and genomic data to explore the potential causal relationship between alcohol consumption and allergic diseases. …”
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4523
Genotyping Genebank Collections: Strategic Approaches and Considerations for Optimal Collection Management
Published 2025-01-01“…Due to the advancement of technology, genotyping and sequencing whole genomes of plant germplasm collections is now feasible. …”
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4524
The Identification of Key Genes and Pathways in Glioma by Bioinformatics Analysis
Published 2017-01-01“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were applied for the enriched pathways. …”
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4525
The future of plant lectinology: Advanced technologies and computational tools
Published 2025-01-01“…Phage display libraries enable the identification of carbohydrate-mimetic peptides and the development of ligands for lectins by presenting diverse peptide libraries on bacteriophages. Genomic and transcriptomic analyses facilitate the exploration of the lectome in various plant species by scanning entire datasets to identify genes that contain lectin motifs—specific conserved amino acid sequences involved in carbohydrate recognition—and lectin domains, the larger structural regions that facilitate and stabilize these interactions. …”
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4526
Liquid Chromatography-Mass Spectrometry-Based Metabolomic Analysis of Metabolites and Metabolic Pathways of Selenium-Enriched Auricularia auricula
Published 2025-02-01“…Kyoto Encyclopedia of Genes and Genomes (KEGG) metabolic pathway analysis found that selenization had a significant effect on lipid and amino acid metabolism. …”
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4527
TRα1 mutant suppresses KLF9 to cause endometrial metaplasia with ectopic IL-33 expression leading to uterine fibrosis and infertility
Published 2025-01-01“…Abstract Thyroid hormone receptors (TRs) mediate the genomic actions of thyroid hormone. Mutations of THRA gene cause a human disease known as resistance to thyroid hormone (RTHα). …”
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4528
Protein C deficiency with recurrent systemic thrombosis associated with compound heterozygous PROC missense variants
Published 2025-02-01“…PCR amplification of genomic DNA spanning these exons followed by Sanger sequencing analysis revealed that the c.76G>A and the synonymous c.423G>T variants were in the same allele, whereas the c.1000G>A variant was on the opposite allele, indicating compound heterozygosity. …”
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4529
Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19
Published 2023-01-01“…We evaluated the identified variants based on the predictive performance of 5 deleteriousness-scoring methods and the 2015 American College of Medical Genetics and Genomics (ACMG) guidelines. The results indicated 299 variants within the ACE2 gene. …”
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4530
Prenatal Identification and Molecular Characterization of Two Simultaneous De Novo Interstitial Duplications of Chromosomal Regions 7p22.1p21.1 and 15q24.1
Published 2018-01-01“…Cytogenetic analysis of cultured amniocytes by conventional chromosome analysis, comparative genomic hybridization, and fluorescence in situ hybridization revealed two interstitial duplications of the chromosomal regions 7p22.1p21.1 and 15q24.1, leading to partial trisomy of 7p and 15q and karyotype 46,XY,dup(7)(p22.1-p21.1),dup (15)(q24.1). …”
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4531
Proteome differences of dental stem cells between permanent and deciduous teeth by data-independent acquisition proteomics
Published 2025-01-01“…Subsequent Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses, along with protein–protein interaction network construction, revealed significant metabolic differences and key regulatory nodes. …”
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4532
Prevalence and Subtype Analysis of Blastocystis hominis Isolated from Patients in the Northeast of Iran
Published 2021-01-01“…Samples were examined by a wet mount, and genomic DNA was extracted from positive samples. Also, PCR was done on the positive samples, and sequencing and phylogenetic analysis were subsequently performed. …”
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4533
Antagonistic functions of CTL1 and SUH1 mediate cell wall assembly in Arabidopsis
Published 2024-03-01“…Abstract Plant genomes contain numerous genes encoding chitinase‐like (CTL) proteins, which have a similar protein structure to chitinase belonging to the glycoside hydrolase (GH) family but lack the chitinolytic activity to cleave the β‐1,4‐glycosidic bond in chitins, polymers of N‐acetylglucosamine. …”
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4534
The impact of PD-L1 polymorphisms on the efficacy of immune checkpoint inhibitors depends on the tumor proportion score: a retrospective study
Published 2025-02-01“…Method Patients treated with immune checkpoint inhibitor monotherapy for non-small cell lung cancer at Kyoto University Hospital until January 2023, with TPS data and biological specimens available for SNP measurement, were eligible for this study. Genomic DNA was extracted from peripheral blood leukocytes. …”
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4535
Dealing With the Complexity of Effective Population Size in Conservation Practice
Published 2024-12-01“…To address the challenges associated with estimating Ne for conservation purposes, the COST Action 18134, Genomic Biodiversity Knowledge for Resilient Ecosystems (G‐BiKE), organized an international workshop that met in August 2022 in Brașov, Romania. …”
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4536
Comprehensive review of mapping climate change impacts on tea cultivation: bibliometric and content analysis of trends, influences, adaptation strategies, and future directions
Published 2025-01-01“…The results show significant progress in understanding the physiological, biochemical, and molecular responses of tea plants to climate-induced stressors, including antioxidant mechanisms, secondary metabolite regulation, and genomic adaptations. Despite these advancements, challenges remain, particularly regarding the combined effects of multiple stressors, long-term adaptation strategies, and the socioeconomic implications of climate change. …”
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4537
An annotated high-content fluorescence microscopy dataset with EGFP-Galectin-3-stained cells and manually labelled outlineszenodo
Published 2025-02-01“…In the context of microscopy-based high-throughput drug and genomic screening and even in smaller scale microscopy experiments, the objects that most often need to be detected are cells. …”
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4538
The metabolomic approach to the assessment of cultivar specificity of Brassica napus L. seeds
Published 2015-07-01“…Recent biomolecular studies tend to involve combinations of different methods and approaches that allow analyzing organisms on the genomic and proteomic levels, as well as on the level of metabolomics. …”
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4539
Comprehensive analysis of cuproptosis-related genes in immune infiltration and development of a novel diagnostic model for acute kidney injury
Published 2024-12-01“…Our study aimed to investigate the involvement of cuproptosis-related genes (CRGs) in AKI.Methods Identification of CRGs was conducted using differential expression analysis, and subsequent Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted using human sequencing profiles. …”
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4540
Pulp stones and kidney stones-related gene: An investigation of single nucleotide polymorphisms in the gene encoding parathyroid hormone
Published 2025-02-01“…The samples were processed, and genomic DNA was used to genotype the rs694, rs6256, and rs307247 SNPs. …”
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