The war inside your mind: unprotected brain battlefields and neuro-vulnerability by Robert McCreight

“… The 21st century featured explosive discoveries, inventions, and finely crafted technologies where the vaguely dangerous and ambiguous mix of genomics, neuroscience, nanotech, robotics, cyber, and other advanced scientific ventures leads to unknown and possibly unpleasant outcomes pose an acute dilemma. …”
Get full text

Mental Health Across the Metabolic Spectrum by Vrinda Saxena, Isaac Marin-Valencia

Get full text

Evaluation of Transforming Growth Factor Beta-1 Gene 869T/C Polymorphism with Hypertension: A Meta-Analysis by Wenquan Niu

Get full text

scCamAge: A context-aware prediction engine for cellular age, aging-associated bioactivities, and morphometrics by Vishakha Gautam, Subhadeep Duari, Saveena Solanki, Mudit Gupta, Aayushi Mittal, Sakshi Arora, Anmol Aggarwal, Anmol Kumar Sharma, Sarthak Tyagi, Rathod Kunal Pankajbhai, Arushi Sharma, Sonam Chauhan, Shiva Satija, Suvendu Kumar, Sanjay Kumar Mohanty, Juhi Tayal, Nilesh Kumar Dixit, Debarka Sengupta, Anurag Mehta, Gaurav Ahuja

“…We present scCamAge, an advanced context-aware multimodal prediction engine that co-leverages image-based cellular spatiotemporal features at single-cell resolution alongside cellular morphometrics and aging-associated bioactivities such as genomic instability, mitochondrial dysfunction, vacuolar dynamics, reactive oxygen species levels, and epigenetic and proteasomal dysfunctions. scCamAge employed heterogeneous datasets comprising ∼1 million single yeast cells and was validated using pro-longevity drugs, genetic mutants, and stress-induced models. scCamAge also predicted a pro-longevity response in yeast cells under iterative thermal stress, confirmed using integrative omics analyses. …”
Get full text

Mitogenomic Phylogenetic Analyses Reveal New Insights into the Taxonomy and Evolution of Parnassiinae Swallowtail Butterflies (Lepidoptera: Papilionidae) by Lu Song, Xiaoxiao Chen, Xiushan Li, Raul Narciso C. Guedes, Youssef Dewer, Suqin Shang, Jingjiang Zhou

“…Mitochondrial genomes provide powerful insights into insect phylogeny and molecular evolution, aiding in the clarification of complex taxonomic relationships. …”
Get full text

De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii by Valentina Mastrantonio, Daniele Porretta, Franco Liberati, Roberta Bisconti, Tiziana Castrignanò, Daniele Canestrelli

“…Abstract Understanding the genomic consequences of hybridization is an essential research focus in global change biology. …”
Get full text

Application of Metabolomics in Thyroid Cancer Research by Anna Wojakowska, Mykola Chekan, Piotr Widlak, Monika Pietrowska

“…However, in some cases, cytological and histological patterns are inconclusive; hence, classification based on histopathology could be supported by molecular biomarkers, including markers identified with the use of high-throughput “omics” techniques. Beside genomics, transcriptomics, and proteomics, metabolomic approach emerges as the most downstream attitude reflecting phenotypic changes and alterations in pathophysiological states of biological systems. …”
Get full text

Rapid Identification and Systematic Mechanism of Flavonoids from Potentilla freyniana Bornm. Based on UHPLC-Q-Exactive Orbitrap Mass Spectrometry and Network Pharmacology by Wei Cai, Kailin Li, Shihan Qin, Pei Xiong, Jie Peng, Silin Shi, Zaiqi Zhang

“…Finally, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were carried out via DAVID. …”
Get full text

The emerging roles of aberrant alternative splicing in glioma by Reda Ben Mrid, Sara El Guendouzi, Marco Mineo, Rachid El Fatimy

“…AS is a process that produces, from a single genomic sequence, several mature messenger RNAs. Splicing of pre-messenger RNAs concerns at least 95% of transcripts and constitutes an important mechanism in gene expression regulation. …”
Get full text

Connecting electronic health records to a biomedical knowledge graph to link clinical phenotypes and molecular endotypes in atopic dermatitis by Francesca Frau, Paul Loustalot, Margaux Törnqvist, Nina Temam, Jean Cupe, Martin Montmerle, Franck Augé

“…Through our analysis, we identified seven subgroups of patients each characterized by clinical and genomic characteristics.…”
Get full text

In Vitro Analyses Reveal the Effect of Synthetic Cytokinin Forchlorfenuron (FCF) on a Septin-Like Protein of Taeniid Cysticerci by Diana G. Rios-Valencia, Edgar O. López-Villegas, Dylan Diaz Chiguer, Adrian Marquez Navarro, Ruben D. Díaz-Martín, Benjamin Nogueda-Torres, Javier R. Ambrosio

“…Cytokinin forchlorfenuron (FCF), a synthetic cytokinin, has been used specifically for the characterization of septins. In spite of genomic evidence of their existence, nothing is known about septin filaments in taeniid cestodes. …”
Get full text

A Hybrid Approach of Using Wavelets and Fuzzy Clustering for Classifying Multispectral Florescence In Situ Hybridization Images by Yu-Ping Wang, Ashok Kumar Dandpat

“…Multicolor or multiplex fluorescence in situ hybridization (M-FISH) imaging is a recently developed molecular cytogenetic diagnosis technique for rapid visualization of genomic aberrations at the chromosomal level. By the simultaneous use of all 24 human chromosome painting probes, M-FISH imaging facilitates precise identification of complex chromosomal rearrangements that are responsible for cancers and genetic diseases. …”
Get full text

A first exploratory comparison of the behaviour of wolves (Canis lupus) and wolf-dog hybrids in captivity by Federica Amici, Simone Meacci, Emmeline Caray, Linda Oña, Katja Liebal, Paolo Ciucci

“…Abstract Extensive introgression of genes from domesticated taxa may be a serious threat for the genomic integrity and adaptability of wild populations. …”
Get full text

1q21.1 Duplication Syndrome and Anorectal Malformations: A Literature Review and a New Case by Maria Minelli, Chiara Palka Bayard de Volo, Melissa Alfonsi, Serena Capanna, Elisena Morizio, Maria Enrica Miscia, Gabriele Lisi, Liborio Stuppia, Valentina Gatta

“…Case presentation: The present case describes a male, referred to us for an ARM, in whom array—comparative genomic hybridization (array-CGH) identified 1q21.1 duplication inherited from his healthy mother. …”
Get full text

Novel MFSD8 Variants in a Chinese Family with Nonsyndromic Macular Dystrophy by Qin Xiang, Yanna Cao, Hongbo Xu, Zhijian Yang, Liang Tang, Ju Xiang, Jianming Li, Hao Deng, Lamei Yuan

“…Ophthalmic examinations were performed, and genomic DNA was extracted from available family members. …”
Get full text

Rapid degradation of DHX36 revealing its transcriptional role by interacting with G‐quadruplex by Ziang Lu, Jinglei Xu, Yuqi Chen, Yuanyuan Zhou, Xiaolu Zhou, Qi Wang, Qi Wei, Shaoqing Han, Ruiqi Zhao, Xiaocheng Weng, Xiaolian Zhang, Xiang Zhou

“…Our results reveal a significant enrichment of G4 structures at DHX36 target sites, predominantly located in active genomic regions. In vitro assays further demonstrate DHX36's interaction with G4 sequences from three specific oncogenes. …”
Get full text

Mitotic Kinases and p53 Signaling by Geun-Hyoung Ha, Eun-Kyoung Yim Breuer

“…Mitosis is tightly regulated and any errors in this process often lead to aneuploidy, genomic instability, and tumorigenesis. Deregulation of mitotic kinases is significantly associated with improper cell division and aneuploidy. …”
Get full text

Some anatomical, morphological and physiological features of the flag leaf in introgressive bread wheat lines with <i>Aegilops columnaris</i> Zhuk. genetic material by Iu. V. Dashtoian, A. V. Kalinina

“…A negative effect of substitutions of chromosomes 2A, 5B, 6A and 6D for chromosomes of the U and X genomes on the size of the flag leaf area was disclosed. …”
Get full text

The role of artificial intelligence and machine learning in predicting and combating antimicrobial resistance by Hazrat Bilal, Muhammad Nadeem Khan, Sabir Khan, Muhammad Shafiq, Wenjie Fang, Rahat Ullah Khan, Mujeeb Ur Rahman, Xiaohui Li, Qiao-Li Lv, Bin Xu

“…AI/ML models can use various data sources, such as clinical information, genomic sequences, microbiome insights, and epidemiological data for predicting AMR outbreaks. …”
Get full text

Molecular Characterization of Chicken Anemia Virus Circulating in Chicken Flocks in Egypt by Mohammed AboElkhair, Alaa G. Abd El-Razak, Abd Elnaby Y. Metwally

“…Although many previous studies reported detection of chicken anemia virus (CAV) in Egypt since 1990, genomic characterization of this circulating CAV has not been published. …”
Get full text