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3861
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders
Published 2016-01-01Get full text
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3862
Modes and mechanisms for the inheritance of mitochondria and plastids in pathogenic protists.
Published 2025-01-01“…However, mutations within the organellar genomes of mitochondria and plastids can lead to drug resistance. …”
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GH inhibits ALV-J replication and restricts cell cycle by activating PI3K/Akt signaling pathway
Published 2025-01-01Get full text
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3865
ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2
Published 2025-01-01Get full text
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3866
Identification of GBN5 as a molecular biomarker of pan-cancer species by integrated multi-omics analysis
Published 2025-01-01“…Materials and methods We employed a multi-omics approach, including transcriptomic, genomic, proteomic, single-cell cytomic, spatial transcriptomic, and genomic data, to explore the prognostic value and potential oncogenic mechanisms of GBN5 across pan-cancers from multiple perspectives. …”
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3867
Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment.
Published 2025-01-01“…Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). …”
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3868
Expanding the Diversity of <i>Actinobacterial Tectiviridae</i>: A Novel Genus from <i>Microbacterium</i>
Published 2025-01-01“…The phages have linear dsDNA genomes 15,438–15,636 bp with 112–120 bp inverted terminal repeats. …”
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3869
Tumor mutational burden quantification from targeted gene panels: major advancements and challenges
Published 2019-07-01“…However, to date WES remains confined to research settings, due to high cost of the large genomic space sequenced. In the clinical setting, instead, targeted enrichment panels (gene panels) of various genomic sizes are emerging as the routine technology for TMB assessment. …”
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3870
DNA Ligase IV Prevents Replication Fork Stalling and Promotes Cellular Proliferation in Triple Negative Breast Cancer
Published 2019-01-01“…DNA damage is a hallmark of cancer, and mutation and misregulation of proteins that maintain genomic fidelity are associated with the development of multiple cancers. …”
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3871
BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts
Published 2009-01-01“…So far, most studies have focused on the role of BRCA-pathways in the maintenance of genomic stability.…”
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3872
Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers
Published 2025-01-01Get full text
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3875
Functional Comparison between Healthy and Multiple Myeloma Adipose Stromal Cells
Published 2020-01-01Get full text
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3876
Diagnostic efficiency of exome-based sequencing in pediatric patients with epilepsy
Published 2025-01-01Get full text
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3877
Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy
Published 2023-01-01“…Genomic sequencing analysis revealed that the genomic aberration landscape of PMME predominated in classical cancer driver genes, with approximately half of PMME cases harboring mutations in BRAF, N/KRAS, and NF1. …”
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