Showing 3,861 - 3,880 results of 5,161 for search '"genome"', query time: 0.07s Refine Results
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    Modes and mechanisms for the inheritance of mitochondria and plastids in pathogenic protists. by Sophie L Collier, Sarah N Farrell, Christopher D Goodman, Geoffrey I McFadden

    Published 2025-01-01
    “…However, mutations within the organellar genomes of mitochondria and plastids can lead to drug resistance. …”
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    Article
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  6. 3866

    Identification of GBN5 as a molecular biomarker of pan-cancer species by integrated multi-omics analysis by Qian Guo, Xinxin Zhong, Zihan Dang, Baiquan Zhang, Zixin Yang

    Published 2025-01-01
    “…Materials and methods We employed a multi-omics approach, including transcriptomic, genomic, proteomic, single-cell cytomic, spatial transcriptomic, and genomic data, to explore the prognostic value and potential oncogenic mechanisms of GBN5 across pan-cancers from multiple perspectives. …”
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  7. 3867

    Impact of developmental state, p53 status, and interferon signaling on glioblastoma cell response to radiation and temozolomide treatment. by Artem Berezovsky, Oluwademilade Nuga, Indrani Datta, Kimberly Bergman, Thais Sabedot, Katherine Gurdziel, Susan Irtenkauf, Laura Hasselbach, Yuling Meng, Claudius Mueller, Emanuel F Petricoin, Stephen Brown, Neeraja Purandare, Sidhesh Aras, Tom Mikkelsen, Laila Poisson, Houtan Noushmehr, Douglas Ruden, Ana C deCarvalho

    Published 2025-01-01
    “…Glioblastoma (GBM) tumors exhibit extensive genomic, epigenomic, and transcriptional diversity, with significant intratumoral heterogeneity, complicating standard treatment approaches involving radiation (RT) and the DNA-alkylating agent temozolomide (TMZ). …”
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  8. 3868

    Expanding the Diversity of <i>Actinobacterial Tectiviridae</i>: A Novel Genus from <i>Microbacterium</i> by Jacqueline M. Washington, Holly Basta, Angela Bryanne De Jesus, Madison G. Bendele, Steven G. Cresawn, Emily K. Ginser

    Published 2025-01-01
    “…The phages have linear dsDNA genomes 15,438–15,636 bp with 112–120 bp inverted terminal repeats. …”
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  9. 3869

    Tumor mutational burden quantification from targeted gene panels: major advancements and challenges by Sara Gandini, Laura Fancello, Pier Giuseppe Pelicci, Luca Mazzarella

    Published 2019-07-01
    “…However, to date WES remains confined to research settings, due to high cost of the large genomic space sequenced. In the clinical setting, instead, targeted enrichment panels (gene panels) of various genomic sizes are emerging as the routine technology for TMB assessment. …”
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  10. 3870

    DNA Ligase IV Prevents Replication Fork Stalling and Promotes Cellular Proliferation in Triple Negative Breast Cancer by Rashmi R. Joshi, Sk Imran Ali, Amanda K. Ashley

    Published 2019-01-01
    “…DNA damage is a hallmark of cancer, and mutation and misregulation of proteins that maintain genomic fidelity are associated with the development of multiple cancers. …”
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    Article
  11. 3871

    BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts by Asta Björk Jonsdottir, Maaike P. G. Vreeswijk, Ron Wolterbeek, Peter Devilee, Hans J. Tanke, Jorunn E. Eyfjörd, Karoly Szuhai

    Published 2009-01-01
    “…So far, most studies have focused on the role of BRCA-pathways in the maintenance of genomic stability.…”
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    Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy by Yu Chen, Xuan Wang, Jie Dai, Li Zhou, Xuefeng Xia, Jun Guo, Xue Bai, Lu Si, Bixia Tang, Chuanliang Cui, Xiaoting Wei, Xinan Sheng, Siming Li, Zhihong Chi, Lili Mao, Bin Lian, Xieqiao Yan, Yan Kong, Caili Li, Xuan Gao, Lirui Tang, Linzi Sun, Zhonghui Qi, Zelong Xu

    Published 2023-01-01
    “…Genomic sequencing analysis revealed that the genomic aberration landscape of PMME predominated in classical cancer driver genes, with approximately half of PMME cases harboring mutations in BRAF, N/KRAS, and NF1. …”
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