Newly isolated halotolerant Gordonia terrae S-LD serves as a microbial cell factory for the bioconversion of used soybean oil into polyhydroxybutyrate by Song Xu, Ruiqin Han, Lidan Tao, Zhipeng Zhang, Junfei Gao, Xinyuan Wang, Wei Zhao, Xiaoxia Zhang, Zhiyong Huang

“…In addition, the whole genome was sequenced, and the PHB biosynthetic pathway and quantitative expression of key genes were delineated in the novel isolated strain. …”
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Phenotypic stability of spring bread wheat regenerant lines by V. Yu. Stupko, A. V. Sidorov

“…Selection of somaclonal variation under callus culture (СС) conditions is one of the methods of undirected genome change induction which has become actively used in the development of cultivars with high adaptive potential. …”
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A Narrative Review of Prognostic Gene Signatures in Oral Squamous Cell Carcinoma Using LASSO Cox Regression by Nur Fatinazwa Mohd Faizal, Saptarsi Shai, Bansi P. Savaliya, Lee Peng Karen-Ng, Rupa Kumari, Rahul Kumar, Vui King Vincent-Chong

“…It is essential to distinguish between cancers arising in the head and neck regions due to significant differences in their etiologies, treatment approaches, and prognoses. As the Cancer Genome Atlas (TCGA) dataset is available in HNSCC, the survival analysis prognosis of OSCC patients based on the TCGA dataset for discovering gene expression-based prognostic biomarkers is limited. …”
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Model systems of human immunodef iciency virus (HIV-1) for in vitro eff icacy assessment of candidate vaccines and drugs against HIV-1 by N. B. Rudometova, D. N. Shcherbakov, A. P. Rudometov, A. A. Ilyichev, L. I. Karpenko

“…Pseudotyped viruses have defective genomes restricting their replication to a single cycle, which renders them harmless compared to infectious viruses. …”
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Evaluation Frequency of Human Papillomavirus and Its Related Genotypes in Women of the General Population Living in 11 Provinces of Iran by Somayeh Hassani, Proshat Sadat Nadji, Anita Mohseni, Marjan Rahnamaye Farzami, Siamak Mirab Samiee, Makan Sadr, Seyed Alireza Nadji

“…The study was performed on 2562 vaginal specimens that were referred to the laboratory of the present study. HPV genome was detected by the nested MY-GP method and papillomavirus genotyping was performed using the PCR multiplex method to identify 19 papillomavirus genotypes. …”
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THE MORPHOGENIC POTENTIAL OF SIBERIAN POTATO CULTIVARS IN TISSUE CULTURES by S. M. Ibragimova, A. V. Romanova, G. Kh. Myzgina, A. V. Kochetov

“…Recent advances in plant  biotechnology have made it possible to produce resistant cultivars by plant genome editing. This approach allows crop modiications that would be diicult to obtain by conventional breeding techniques. …”
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Potato spindle tuber viroid by A. V. Kochetov, A. Y. Pronozin, N. V. Shatskaya, D. A. Afonnikov, O. S. Afanasenko

“…This association between the small segments of viroid genomic RNAs complementary to the untranslated regions of cellular mRNAs and disease symptoms provides a way for new resistant cultivars to be developed by genetic editing. …”
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A Novel Prognostic Signature Revealed the Interaction of Immune Cells in Tumor Microenvironment Based on Single-Cell RNA Sequencing for Lung Adenocarcinoma by Xing Jin, Zhengyang Hu, Qihai Sui, Mengnan Zhao, Jiaqi Liang, Zhenyu Liao, Yuansheng Zheng, Hao Wang, Yu Shi

“…Furthermore, there was a correlation between risk score and tumor-infiltrating immune cells and tumor genomics abnormity. Patients with higher risk scores had a significantly lower immunotherapy response rate. …”
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Spatio‐Temporal Changes in Effective Population Size in an Expanding Metapopulation of Eurasian Otters by Nia Evelyn Thomas, Elizabeth A. Chadwick, Michael W. Bruford, Frank Hailer

“…We obtained clear bottleneck signals in East England, and signals of recent population expansion in Wales and South West England in some analyses, consistent with national otter surveys and recent findings from whole‐genome sequencing. Analyses that did not account for spatial genetic structuring yielded strong spurious signals of United Kingdom‐wide population expansion, and Ne estimates from these analyses were suppressed by a factor of 3–4. …”
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Correlation among blastocoel fluid DNA level, apoptotic genes expression and preimplantation aneuploidy by Fattaneh Khajehoseini, Zahra Noormohammadi, Poopak Eftekhari-Yazdi, Hamid Gourabi, Reza Pazhoomand, Shirzad Hosseinishenatal, Masood Bazrgar

“…Following BF aspiration and whole genome amplification, BF-DNA level was quantified. …”
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Poly ADP-Ribosylation in a Plant Pathogenic Oomycete <i>Phytophthora infestans</i>: A Key Controller of Growth and Host Plant Colonisation by Viktoriya O. Samarskaya, Sofya Koblova, Tatiana Suprunova, Eugene A. Rogozhin, Nadezhda Spechenkova, Sofiya Yakunina, Andrew J. Love, Natalia O. Kalinina, Michael Taliansky

“…Here, we show that the <i>Phytophthora infestans</i> genome contains two PARP-like protein genes (PiPARP1 and PiPARP2), and provide evidence of PARylation activity for one of them (PiPARP2). …”
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Upregulated GSDMB in Clear Cell Renal Cell Carcinoma Is Associated with Immune Infiltrates and Poor Prognosis by Yuanshan Cui, Zhongbao Zhou, Yumeng Chai, Yong Zhang

“…The transcriptional expression profiles of GSDMB in ccRCC tissues in addition to normal tissues were retrieved from The Cancer Genome Atlas (TCGA) and additionally verified in a different independent cohort, which was obtained from the Gene Expression Omnibus (GEO) database. …”
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Phage display as a tool for identifying HIV-1 broadly neutralizing antibodies by A. N. Chikaev, A. P. Rudometov, Yu. A. Merkulyeva, L. I. Karpenko

“…Each phage particle in a library displays peptides or proteins fused to its coat protein and simultaneously carries the DNA sequence encoding the displayed peptide/protein in its genome. The biopanning procedure allows isolation of specific clones for almost any target, and due to the physical link between the genotype and the phenotype of recombinant phage particles it is possible to determine the structure of selected molecules. …”
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Causal Effects of Sleep Traits on Angina Pectoris: Mediation by Cardiovascular Risk Factors by Zeng C, Ke Y, Li H, Zhang C, Chen J, Chen M

“…Our study aims to declare the causality of sleep traits on AP by Mendelian randomization (MR) analyses.Methods: Genome-wide association study (GWAS) data of sleep traits (sleep duration, insomnia, nap during day, chronotype, getting up in morning, narcolepsy, snoring) were obtained from the UK Biobank. …”
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Common themes in architecture and interactions of prokaryotic PolB2 and Pol V mutasomes inferred from in silico studies by Kęstutis Timinskas, Albertas Timinskas, Česlovas Venclovas

“…We used highly accurate AlphaFold structural models, coupled with protein sequence and genome context analysis to comprehensively characterize PolB2 and its associated proteins, PPB2, a small helical protein, and iRadA, a catalytically inactive Rad51 homolog. …”
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Polymorphism of CLE gene sequences in potato by M. S. Gancheva, M. R. Losev, A. A. Gurina, L. O. Poliushkevich, I. E. Dodueva, L. A. Lutova

“…All potato species taken for analysis had homologues of previously identified S. phureja CLE genes; at the same time, the CLE42 gene, which is absent from the S. phureja genome, is present in all other analyzed potato species. …”
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Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independently of beta-tubulin. by J B Collins, Clayton M Dilks, Steffen R Hahnel, Briana Rodriguez, Bennett W Fox, Elizabeth Redman, Jingfang Yu, Brittany Cooke, Kateryna Sihuta, Mostafa Zamanian, Peter J Roy, Frank C Schroeder, John S Gilleard, Erik C Andersen

“…However, mutations in beta-tubulin alone do not fully explain all BZ resistance. We performed a genome-wide association study using a genetically diverse panel of Caenorhabditis elegans strains to identify loci that contribute to resistance to the BZ drug thiabendazole (TBZ). …”
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New insights into the N-glycomes of Dictyostelium species by Alba Hykollari, Daniel Malzl, Chunsheng Jin, Carina Eschenbach, Kristína Kianičková, Iain B.H. Wilson, Katharina Paschinger

“…In the present study, we have examined the N-glycans of two other Dictyostelium species, D. purpureum, whose genome is also sequenced, and D. giganteum. The detailed glycomic analysis of their fruiting bodies was based on isomeric separation of the glycan structures by HPLC, followed by mass spectrometry in combination with enzymatic digests and chemical treatments. …”
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Revealing study and breeding implications for production traits and tail characteristics in Simmental cattle by GWAS by Jie Wang, Na Shen, Kaisen Zhao, Jiayu Liao, Genglong Jiang, Jianghai Xiao, Xianbo Jia, Wenqiang Sun, Songjia Lai

“…The study recorded phenotype data from 183 Simmental cattle and performed a Genome-Wide Association Study (GWAS) analysis to elucidate the genetic mechanisms underlying milk production, body size traits, and tail characteristics. …”
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Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes by K. V. Ustyantsev, E. V. Berezikov

“…By reanalyzing the existing genome and transcriptome data of M. lignano, we estimate that 30 % of its genes are SL trans-spliced, 15 % are organized in operons, and almost 40 % are both SL trans-spliced and in operons. …”
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