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3001
Association between wide-ranging food intake and Parkinson’s disease: a comprehensive mendelian randomization study
Published 2025-01-01“…Utilizing data from large-scale genome-wide association studies (GWAS) and dietary databases, we constructed genetic instruments for various dietary factors, including fruit, vegetable, meat, fish, dairy, and grain intake, among others, totaling 170 different food items. …”
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3002
Screening for transcriptomic associations with Swine Inflammation and Necrosis Syndrome
Published 2025-01-01“…For this purpose, the three to five least affected (SINS-low) and most SINS affected (SINS-high) 3d-old piglets, each of three boars, a relatively SINS stable Duroc boar (DU), a relatively stable Pietrain boar (PI+) and a highly susceptible Pietrain boar (PI-) were selected from 27 litters of mixed semen to minimize environmental effects. Results A genome-wide expression experiment revealed a huge set of differentially expressed genes that are involved in vasculitis, inflammation and necrosis, keratinization and erythrocyte epitopes. …”
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3003
Automation-aided construction and characterization of Bacillus subtilis PrsA strains for the secretion of amylases
Published 2025-01-01“…To achieve this, six genome-reduced strains and nine PrsA proteins were systematically selected based on their cultivation performance and the production of two reference amylases. …”
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3004
Results of scientific expedition to natural biotopes of the Republic of Tyva in 2019 with the purpose of infectious disease monitoring in wild bird populations
Published 2020-06-01“…Two samples from European herring gulls were positive for avian influenza type A virus genome and subtype H13N6 was identified in one of them. …”
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3005
Mixed Gastric Carcinomas Show Similar Chromosomal Aberrations in Both their Diffuse and Glandular Components
Published 2006-01-01“…One of the hallmarks of gastric cancer is chromosomal instability resulting in abnormal DNA copy number changes throughout the genome. Mixed gastric carcinomas constitute a rare histological entity, containing the two main histological phenotypes (diffuse and intestinal). …”
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3006
MAIP1-Related Tumor Immune Infiltration: As a Potential Prognostic Biomarker for Esophageal Cancer
Published 2022-01-01“…We obtained RNA-seq datasets and corresponding clinical data for EC patients from the Cancer Genome Atlas (TCGA) database via the UCSC Xena browser to extract MAIP1 expression and plot survival curves to determine their prognosis. …”
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3007
Structuring the genetic collection of sunflower
Published 2025-01-01“…Background. The XRQ sunflower genome has been sequenced but not yet fully annotated, and not all candidate genes for most traits have been identified. …”
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3008
PPIH is a novel diagnostic biomarker associated with immune infiltration in cholangiocarcinoma
Published 2025-02-01“…Methods We analyzed the expression levels, prognostic significance, and diagnostic efficiency of PPIH in CHOL using data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets, coupled with gene enrichment analyses. …”
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3009
Molecular Detection and Phylogenetic Analysis of the alkB Gene in Klebsiella oxytoca Strains Isolated from the Gut of Tenebrio molitor
Published 2024-01-01“…The alkB gene sequence identical to fourteen alkB gene sequences derived from Actinobacteria whole genome was detected in Klebsiella oxytoca for the first time to the best of our knowledge. …”
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3010
A method for siRNA-mediated knockdown of target genes in RA-induced neurogenesis using P19 cells
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3011
Minimization of the Bacillus subtilis divisome suggests FtsZ and SepF can form an active Z-ring, and reveals the amino acid transporter BraB as a new cell division influencing fact...
Published 2025-01-01“…Viability of the multiple deletion mutant was not greatly affected, although the frequency of cell division was considerably reduced. Whole genome sequencing suggested that the construction of this minimal divisome strain was also possible due to the accumulation of suppressor mutations. …”
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3012
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3013
Analysis of polymorphism at the <i>FaRca1</i> locus to identify strawberry genotypes resistant to <i>Colletotrichum acutatum</i>
Published 2025-01-01“…Promising genetic sources for marker-assisted breeding are strawberry cultivars combining several resistance factors in the genome: ‘Borovitskaya’ and ‘Aprica’ (FaRca1 and Rca2 anthracnose resistance loci), ‘Korona’ and ‘Ostara’ (FaRca1 anthracnose resistance locus, and 08 To-f powdery mildew resistance locus), and ‘Bylinnaya’ (FaRca1 anthracnose resistance locus, 08 To-f powdery mildew resistance locus, and Rpf1 red stele root rot resistance locus).…”
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3014
Effective resistance to powdery mildew in Aegilops L. accessions
Published 2020-10-01“…As a result of the tests, susceptibility to powdery mildew was shown in all Aegilops accessions of the D-genome group; all the studied representatives of Ae. speltoides, Ae. caudata and Ae. biuncialis were highly resistant to powdery mildew.…”
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3015
Tissue-specific effects of benzo[a]pyrene and DDT on microRNA expression profile in female rats
Published 2018-04-01“…Using in silico methods, an analysis of the rat genome was carried out to find microRNAs putatively regulated by AhR (aryl hydrocarbon receptor) and CAR (constitutive androstane receptor), activated by BP and DDT, respectively. …”
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3016
Genetic markers for the resistance of honey bee to Varroa destructor
Published 2020-12-01“…The second part focuses on research aimed at searching for loci and candidate genes associated with resistance to varroosis by mapping quantitative traits loci and genome-wide association studies. The third part summarizes studies of the transcriptome profile of Varroa resistant bees. …”
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3017
The content of yellow pigments in durum wheat (Titicum durum Desf.) grains: biosynthesis, genetic control, marker selection
Published 2020-08-01“…Molecular labeling of quantitative trait loci (QTL) that control the synthesis of the carotenoid pigment and the yellowness index (YI) found that they are distributed across all chromosomes of the durum wheat genome. The main QTLs, which determine 60 % of the variation of the trait, were mapped to 7AL and 7BL chromosome. …”
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3018
Expression and clinical significance of disulfidptosis-related LncRNA in gastric cancer
Published 2024-09-01“…Methods The multi-omics features of disulfidptosis genes in gastric cancer were first analyzed based on The Cancer Genome Atlas(TCGA) database. DRLncs were further screened, and disulfidptosis related gene recurrence score (DRG-RS) model was constructed to predict the overall survival(OS) and correlation with the clinical characteristics of gastric cancer patients. …”
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3019
Behçet's Disease (Adamantiades-Behçet's Disease)
Published 2011-01-01“…Bes-1 gene encoded partial S. sanguinis genome which is highly homologous with retinal protein, and 65 kD heat shock protein (Hsp-65) released from streptococci is playing an important role with human Hsp-60 in the pathogenesis of ABD. …”
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3020
Toll-like receptor 4 pathway evolutionary trajectory and functional emergence
Published 2025-01-01“…Our previous work on pan-genome-wide survey, indicates Callorhincus milli to be the ancestral organism with both TRAM and TRIF proteins.MethodsTo gain a deeper insight into the protein function and to compare them with Homo sapiens adaptor proteins, we modeled the docking of the TRAM–TRIF complex of representative organisms across various taxa. …”
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