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2961
Analysis of Prostate Cancer Susceptibility Variants in South African Men: Replicating Associations on Chromosomes 8q24 and 10q11
Published 2015-01-01“…Genome-wide association studies (GWAS) have implicated single nucleotide polymorphisms (SNPs) on chromosomes 2p15, 6q25, 7p15.2, 7q21, 8q24, 10q11, 10q26, 11q13, 17q12, 17q24, 19q13, and Xp11, with prostate cancer (PCa) susceptibility and/or tumour aggressiveness, in populations of African, European, and Asian ancestry. …”
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2962
Comparison of the evolutionary patterns of DNA repeats in ancient and young invertebrate species flocks of Lake Baikal
Published 2023-07-01“…DNA repeat composition of low coverage (0.1–0.5) genomic libraries of four amphipods species endemic to Lake Baikal (East Siberia) and four endemic gastropod species of the fam. …”
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2963
Leptospira and Inflammation
Published 2012-01-01“…The recent sequencing of the Leptospira genome has increased our knowledge about this pathogen. …”
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2964
Systematic and Cell Type-Specific Telomere Length Changes in Subsets of Lymphocytes
Published 2016-01-01“…Telomeres, the protective DNA-protein complexes at the ends of linear chromosomes, are important for genome stability. Leukocyte or peripheral blood mononuclear cell (PBMC) telomere length is a potential biomarker for human aging that integrates genetic, environmental, and lifestyle factors and is associated with mortality and risks for major diseases. …”
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2965
DETECTION OF PORCINE CIRCOVIRUS TYPE 3 IN RUSSIAN PIG HOLDINGS
Published 2019-10-01“…A total of 280 samples of biological materials of different types (organs, tissues, stillborn piglets) collected from domestic pigs with respiratory, reproductive and neurological disorders, dermatitis and from emaciated pigs were tested and PCV-3 genome was detected in 11 samples from 9 holdings located in 5 regions of the Russian Federation. …”
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2966
Development and validation of PCR marker array for molecular selection towards spring, vernalization-independent and winter, vernalization-responsive ecotypes of white lupin (Lupin...
Published 2025-01-01“…Abstract White lupin (Lupinus albus L.) is an ancient grain legume that is still undergoing improvement of domestication traits, including vernalization-responsiveness, providing frost tolerance and preventing winter flowering in autumn-sowing agriculture, and vernalization-independence, conferring drought escape by rapid flowering in spring-sowing. A recent genome-wide association study highlighted several loci significantly associated with the most contrasting phenotypes, including deletions in the promoter of the FLOWERING LOCUS T homolog, LalbFTc1, and some DArT-seq/silicoDArT loci. …”
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2967
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2968
The causal impact of smoking behavior on osteoarthritis: a Mendelian randomization analysis
Published 2025-01-01“…The purpose of this study was to use Mendelian randomization (MR) analysis to investigate the causal relationship between smoking phenotypes and OA risk from a genetically informed standpoint.MethodsAs instrumental variables (IVs) based on single nucleotide polymorphisms (SNPs), this study used the summary-level data of corresponding genome-wide association study (GWAS) for five smoking phenotypes involving 1,694,781 samples. …”
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2969
Presence of the Anopheles culicifacies complex species A in southeast Iran
Published 2025-01-01“…DNA was extracted from mosquito specimens, and the D3 region of the 28S rDNA gene and a segment of the COII gene from the mitochondrial genome (mtDNA) were targeted for amplification and sequencing. …”
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2970
Impact of Mediterranean Diet Adherence on the Incidence of New‐Onset Hypertension in Adults With Obesity in Korea: A Nationwide Cohort Study
Published 2025-01-01“…We used data from the Korean Genome and Epidemiology Study, a population‐based prospective cohort study. …”
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2971
The Single-Nucleotide Polymorphism (SNP) Validity to Detect Omicron Variants
Published 2023-01-01“…Variants of SARS-CoV-2 are determined by the whole genome sequencing (WGS) assay, which is time-consuming, with limited availability (only in several laboratories). …”
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2972
Low dimensionality of phenotypic space as an emergent property of coordinated teams in biological regulatory networks
Published 2025-02-01“…Summary: Cell-fate decisions involve coordinated genome-wide expression changes, typically leading to a limited number of phenotypes. …”
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2973
Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery
Published 2018-01-01“…Sex-combined and sex-stratified association testing was done between adipose measures and 1,233 disease diagnoses and 37 clinical laboratory measures. A genome-wide association study (GWAS) for adipose measures was also performed. …”
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2974
The mutational landscape of Staphylococcus aureus during colonisation
Published 2025-01-01“…Survival and persistence during colonisation are likely major drivers of S. aureus evolution. Here we applied a genome-wide mutation enrichment approach to a genomic dataset of 3060 S. aureus colonization isolates from 791 individuals. …”
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2975
Validation of <i>Monilinia fructicola</i> Putative Effector Genes in Different Host Peach (<i>Prunus persica</i>) Cultivars and Defense Response Investigation
Published 2025-01-01“…<i>M. fructicola</i> putative virulence factors have been predicted by genome investigations. The pathogen interaction with the host was validated. …”
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2976
GBS-DP: a bioinformatics pipeline for processing data coming from genotyping by sequencing
Published 2023-12-01“…It has been applied to genetic mapping, molecular marker discovery, genomic selection, genetic diversity studies, variety identification, conservation biology and evolutio nary studies. …”
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2977
Concordance between Immunohistochemistry and Microarray Gene Expression Profiling for Estrogen Receptor, Progesterone Receptor, and HER2 Receptor Statuses in Breast Cancer Patients...
Published 2018-01-01“…Gene expression profiling was performed using the GeneChip Human Genome U133 Plus 2.0 arrays (Affymetrix Inc). Immunohistochemical staining for estrogen receptor, progesterone receptor, and HER2 status was performed using standard methods at a CAP-accredited pathology laboratory. …”
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2978
Sulfatase modifying factor 2 as a predictive biomarker for urothelial carcinoma
Published 2025-02-01“…High SUMF2 mRNA levels were associated with poor overall survival (OS) and disease-free survival (DFS) in bladder UC (BLCA) from The Cancer Genome Atlas (TCGA) dataset. High SUMF2 protein levels were associated with grade (P < 0.001), T status (P = 0.01), and stage (P = 0.006) in patients with BLCA. …”
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2979
Role of bovine respiratory syncytial virus in etiology of respiratory diseases on milk farms
Published 2021-03-01“…With the help of real-time PCR the virus genome was detected in lungs (13.1%), in exudate from trachea, bronchi and nasal sinuses (6.0%), in nasal discharge (4.0%) and in bronchi (1.7%). …”
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2980
Removing limitations surrounding terpenoid biosynthesis by biotechnological techniques in Ferula sp.: A review
Published 2025-03-01“…Recently, via functional genomics, omics technologies, and high-throughput analytical techniques, our understanding about terpenoid biosynthesis and regulation has been deepened, paving the way for the overproduction of target terpenoids. …”
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