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2721
A Comprehensive Methodological Review of Major Developments in Bioinformatics Pipelines for Transcriptomic Data Analysis
Published 2025-01-01“…Materials and Methods: This review highlights recent software and database improvements for processing RNA-Seq data, including steps like matching sequences to the genome, reconstructing RNA molecules, and measuring RNA abundance. …”
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2722
Microarray Profiling of Lymphocytes in Internal Diseases With an Altered Immune Response: Potential and Methodology
Published 2005-01-01“…Lymphocytes express more than 75% of the human genome, and, being an important part of the immune system, they play a central role in the pathogenesis of asthma, RA, and SLE. …”
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2723
Faster model-based estimation of ancestry proportions
Published 2024-12-01“…We further show that fastmixture runs approximately 30$\times$ faster than ADMIXTURE on both simulated and empirical data from the 1000 Genomes Project such that our model-based approach scales to much larger sample sizes than previously possible.…”
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2724
Modeling Alzheimer’s Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns
Published 2016-01-01“…Indeed, human induced pluripotent stem cells can be differentiated into disease-relevant cell types that recapitulate the unique genome of a sporadic AD patient or family member. …”
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2725
From phylogenomics to breeding: Can universal target capture probes be used in the development of SNP markers for kinship analysis?
Published 2025-01-01“…Abstract Premise Leveraging DNA markers, particularly single‐nucleotide polymorphisms (SNPs), in parentage analysis, sib‐ship reconstruction, and genomic relatedness analysis can enhance plant breeding efficiency. …”
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2726
Post-mortem and histological lesions in the European minks (Mustela lutreola) induced by spontaneous infection with coronavirus SARS-CoV-2
Published 2021-07-01“…Profound and detailed studies of the virus circulation in the European mink population and the clinical manifestations of the disease, comprehensive approaches to the disease diagnosis, including epidemiological studies, clinical and post-mortem examinations, molecular genetic laboratory diagnostics (polymerase chain reaction and full-genome sequencing) contributed to better understanding of the disease features. …”
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2727
Molecular Characterization of Wild and Cultivated Strawberry (Fragaria × ananassa) through DNA Barcode Markers
Published 2022-01-01“…Initially, the efficacy of eight DNA barcode markers was analyzed based on the amplification and sequencing of the genome of selected Fragaria species. The resultant sequences were analyzed using BLAST, MEGA 7.0, and Bio Edit software. …”
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2728
Why Rights are Wrong in ASEAN and Beyond: A Critique of the Foundations of Universal Human Rights
Published 2020-05-01“…Part Two then examines whether the original axiomatic listing of human rights or an iteration of human rights founded upon the human genome or a Kantian underpinning can legitimise human rights and, if not, whether reference to the human soul made in the image of God with its natural law may substantiate the human rights project, perhaps, articulated as congruent with the purpose and design courts now recognise in the natural laws found in every ecosystem of nature. …”
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2729
Pharmacogenetics of Oral Antidiabetic Drugs
Published 2013-01-01“…The function of a gene variant near ATM gene identified by a genome-wide association study is not elucidated so far. …”
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2730
Relationship between Maternal Immunological Response during Pregnancy and Onset of Preeclampsia
Published 2014-01-01“…The maternal immunological tolerance to the semiallogeneic fetus becomes greater in egg donation pregnancies with unrelated donors as the complete fetal genome is allogeneic to the mother. Instead of being rejected, the allogeneic fetus is tolerated by the pregnant woman in egg donation pregnancies. …”
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2731
History, status and genetic characteristics of native cattle breeds from the Republic of Kazakhstan
Published 2024-07-01“…The study examined the genetic structure of the Kazakh white-headed and Alatau breeds based on whole-genome SNP genotyping. Unique genetic components characterizing Kazakhstan cattle breeds were described, and comparisons were made with genetic data from other breeds. …”
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2732
The causal association of cheese intake with type 2 diabetes mellitus: results from a two-sample Mendelian randomization study
Published 2024-05-01“…Material and methods Summary cheese intake statistics were obtained from UK Biobank and publicly available genome-wide association studies (GWAS) for type 2 diabetes from IEU OpenGWAS, FinnGen Biobank, EBI GWAS, and Biobank Japan. …”
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2733
A hypothesis about interrelations of epigenetic factors and transposable elements in memory formation
Published 2024-09-01“…The data obtained suggest that transposons, which are genome sensors highly sensitive to various environmental and internal influences, form memory at the nuclear coding level. …”
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2734
A user-friendly software to accurately count and measure cysts from the parasitic nematode Heterodera glycines
Published 2025-02-01“…Researchers and breeders typically employ exploratory methods such as Genome-Wide Association Studies or Quantitative Trait Loci mapping to identify genes linked to resistance. …”
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2735
PIWI proteins and piRNAs: key regulators of stem cell biology
Published 2025-02-01“…Similarly, in Drosophila intestinal stem cells, the PIWI protein Piwi regulates metabolic pathways and genome integrity, impacting longevity and gut homeostasis. …”
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2736
Heterosis: current advances in the search for molecular mechanisms
Published 2016-12-01“…To date, differences in genome organization, gene expression and epigenetic status have been found between hybrids and their parents. …”
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2737
Decoding the Methylation Patterns of ABC Transporters in Colorectal Cancer
Published 2024-10-01“…Survival analysis demonstrated the correlation between DNA methylation of individual CpG sites and patient survival probability in colon and rectal adenocarcinoma datasets from The Cancer Genome Atlas. The study provides insights into the epigenetic landscape of ABC genes in CRC, highlighting their potential roles in drug resistance, disease initiation, and progression. …”
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2738
The Impact of Interferon Lambda 3 Gene Polymorphism on Natural Course and Treatment of Hepatitis C
Published 2012-01-01“…Very recently, three landmark genome-wide association studies identified single nucleotide polymorphisms near the interleukin 28B (IL28B) region which were more frequent in responders to treatment. …”
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2739
Nuclear Protein 1 Expression Is Associated with PPARG in Bladder Transitional Cell Carcinoma
Published 2023-01-01“…However, the role of Nuclear protein 1 in bladder transitional cell carcinoma (BTCC) is still unclear. Methods. The Cancer Genome Atlas database and immunohistochemical analysis were adopted to evaluate Nuclear protein 1 expression in BTCC. …”
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2740
CLONING OF GENES ENCODING TRANSMEMBRANE PROTEINS AND PROTEINS RESPONSIBLE FOR AFRICAN SWINE FEVER VIRUS VIRULENCE
Published 2018-07-01“…Proportion of cloned virus genes was 3.01% of Krasnodar 07/17 isolate genome, hence, total amount of the clone library has reached 7.82%.…”
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