Persistent Mosaicism for 12p Duplication/Triplication Chromosome Structural Abnormality in Peripheral Blood by Amy L. Shackelford, Laura K. Conlin, Marybeth Hummel, Nancy B. Spinner, Sharon L. Wenger

“…Utilization of fluorescence in situ hybridization (FISH) identified three copies of probes from the end of the short arm of chromosome 12 (TEL(12p13) locus and the subtelomere (12p terminal)) on the structurally abnormal chromosome 12. Genome-wide SNP array analysis revealed that the regions of duplication and triplication were of maternal origin. …”
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Raise of short-stemmed vaviloid branched spike lines and their cytogenetics by A. J. Aliyeva, S. P. Mehdiyeva, R. K. Kerimova

“…The chromosome composition of one of the lines (378/3SD) was characterized by fluorescence in situ hybridization (FISH) and genome in situ hybridization (GISH), and it was identified as a substitution line. …”
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Differential expression of plasma extracellular vesicle miRNAs as biomarkers for distinguishing psoriatic arthritis from psoriasis by Kexiang Yan, Jie Zhu, Mengmeng Zhang, Fuxin Zhang, Bing Wang, Ling Han, Qiong Huang, Yulong Tang, Yuan Li, Nikhil Yawalkar, Zhenghua Zhang, Zhenmin Niu, Xiangxiang Pan

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Urinary Catheter Colonization by Multidrug-Resistant Cedecea neteri in Patient with Benign Prostatic Hyperplasia by Peter S. Ginn, Serina B. Tart, Stephen M. Sharkady, Dorothea K. Thompson

“…This C. neteri isolate was resistant or intermediate to second-generation cephalosporins, penicillins, and certain β-lactamase inhibitor/β-lactam combinations. Analysis of whole genome sequence information for a representative C. neteri strain indicated the presence of multiple open reading frames with sequence similarity to β-lactamases, including a chromosome-encoded AmpC β-lactamase and metallo-β-lactamases, consistent with the resistance phenotype of this bacterium. …”
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An Interstitial 4q Deletion with a Mosaic Complementary Ring Chromosome in a Child with Dysmorphism, Linear Skin Pigmentation, and Hepatomegaly by J. Carter, H. Brittain, D. Morrogh, N. Lench, J. J. Waters

“…Interstitial deletions of 4q are rarely reported, vary in size, and have limited genotype-phenotype correlations. Here, genome-wide array CGH analysis identified a 21.6 Mb region of copy number loss at 4q12-q21.1 in a patient diagnosed with dysmorphism, linear skin pigmentation, and hepatomegaly. …”
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EVALUATION OF ASSISTANCE TOOLS FOR DIAGNOSIS OF DISEASES BY APPROACHING TO PERSONALIZED MEDICINE ON METAGENOMIC DATA by Phan Tấn Tài, Tạ Đặng Vĩnh Phúc, Phan Nguyễn Minh Thảo, Nguyễn Thị Ngọc Chăm, Đào Công Tính, Phạm Huỳnh Ngọc, Nguyễn Thanh Hải

“…In recent years, Metagenomic data, or “multi-genome” data, has been increasingly used for research in “personalized medicine” approaches with the purpose of improving and enhancing effectiveness in human health care. …”
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Tumor-initiating and metastasis-initiating cells of clear-cell renal cell carcinoma by Dinh-Xuan Pham, Tien Hsu

“…A majority of ccRCC is characterized by the loss of the von Hippel-Lindau (VHL) tumor suppressor gene function. Recent advances in genome analyses of ccRCC indicate that in ccRCC, tumor-initiating cells (TICs) and metastasis-initiating cells (MICs) are two distinct groups of progenitors. …”
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Single-Cell Sequencing Technology in Oncology: Applications for Clinical Therapies and Research by Baixin Ye, Qingping Gao, Zhi Zeng, Creed M. Stary, Zhihong Jian, Xiaoxing Xiong, Lijuan Gu

“…Single-cell sequencing (SCS) technology has been recently employed for analyzing the genetic polymorphisms of individual cells at the genome-wide level. SCS requires (1) precise isolation of the single cell of interest; (2) isolation and amplification of genetic material; and (3) descriptive analysis of genomic, transcriptomic, and epigenomic data. …”
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Screening and Functional Verification of Selectable Marker Genes for Cordyceps militaris by Haiwei Lou, Yu Zhao, Renyong Zhao, Zhiwei Ye, Junfang Lin, Liqiong Guo

“…The bar gene of the vector pCAMBIA0390-Bar was successfully integrated into the C. militaris genome and could be highly expressed in the transformants of C. militaris. …”
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Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen by Siew Mei Joyce-Tan, Shamsul Mohd Zain, Munavvar Zubaid Abdul Sattar, Nor Azizan Abdullah

“…Genome-wide association studies (GWAS) have been successfully used to call for variants associated with diseases including type 2 diabetes mellitus (T2DM). …”
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The Application of Single-Cell RNA Sequencing in Vaccinology by Andrés Noé, Tamsin N. Cargill, Carolyn M. Nielsen, Andrew J. C. Russell, Eleanor Barnes

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Causal role of ischemic heart disease in ovarian cancer subtypes by Jianhai Chen, Huabin He, Ling Gao

“…Methods A two-sample MR analysis was conducted using genetic instruments for IHD from large-scale genome-wide association studies (GWAS). The inverse-variance weighted (IVW) method was used as the primary analysis, supported by MR-Egger, weighted median, and MR-PRESSO for sensitivity analyses. …”
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IDENTIFICATION OF LEAF RUST RESISTANCE GENES IN SPECIES OF AEGILOPS L., SYNTHETIC FORMS, AND INTROGRESSION LINES OF COMMON WHEAT by E. R. Davoyan, R. O. Davoyan, I. V. Bebyakina, O. R. Davoyan, Yu. S. Zubanova, A. M. Kravchenko, A. N. Zinchenko

“…The synthetic forms Avrolata and Avrodes, with the substitution of the genomes of A е. umbellulata and Aе. speltoides, respectively, for the wheat D-genome, possess Lr9 and Lr35 genes. …”
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Relationship between Periodontitis and Glaucoma: A Cross-Sectional Study by Soo Hwan Byun, Dae Myoung Yoo, Minwook Chang, Hyo Geun Choi, Seok Jin Hong

“…This prospective cohort study used epidemiological data from the Korean Genome and Epidemiology Study performed between 2004 and 2016. …”
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Microscopic Analysis of Severe Structural Rearrangements of the Plant Endoplasmic Reticulum and Golgi Caused by Overexpression of Poa semilatent virus Movement Protein by Andrey G. Solovyev, Joachim Schiemann, Sergey Y. Morozov

“…Three movement proteins coded by the “triple gene block” (TGB) and named TGBp1, TGBp2 and TGBp3 have distinct functions in viral transport. TGBp1 binds viral genomic RNAs to form ribonucleoprotein complexes representing the transport form of viral genome, while TGBp2 and TGBp3 are necessary for intracellular delivery of such complexes to plasmodesmata. …”
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Semi-automatic construction of heterogeneous data schema based on structure and context-aware recommendation by Nan Yin, Junheng Liang, Xi Guo, Xue Jiang, Jie He, Xiaotong Zhang

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The genetic architecture of resistance to flubendiamide insecticide in Helicoverpa armigera (Hübner). by Douglas Amado, Eva L Koch, Erick M G Cordeiro, Wellingson A Araújo, Antonio A F Garcia, David G Heckel, Gabriela Montejo-Kovacevich, Henry L North, Alberto S Corrêa, Chris D Jiggins, Celso Omoto

“…We explore the genetic architecture of H. armigera resistance to a widely used insecticide, flubendiamide, using two complementary approaches: genome-wide association studies (GWAS) in wild-caught samples and quantitative trait locus (QTL) mapping in a controlled cross of susceptible and resistant laboratory strains. …”
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The genetic architecture of local adaptation in a cline by Laroche, Fabien, Lenormand, Thomas

“…It has been repeatedly proposed that the localization of these genes in the genome may not be random, but could be an evolved feature. …”
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p53 Mutations and DNA Ploidy in Colorectal Adenocarcinomas by Paola Campomenosi, Paola Assereto, Massimo Bogliolo, Gilberto Fronza, Angelo Abbondandolo, Antonella Capasso, Patrizia F. Bellomo, Roberto Monaco, Anna Rapallo, Andrea Sciutto, Roberto Orecchia, Elio Geido, Walter Giaretti

“…The p53 tumour suppressor gene has an important role in the the maintenance of genome stability and its mutational inactivation may be at the origin of aneuploidy in cancer cells. …”
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Causal Relationship Between Psoriasis and Bullous Pemphigoid: A Mendelian Randomization Analysis by Xiaoxue Wang, Zexin Zhu

“…Objectives: In order to explore the causal relationship between psoriasis and BP, we performed a bidirectional two-sample Mendelian randomization (MR) study. Methods: Genome-wide association study (GWAS) data related to psoriasis and BP were collected. …”
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