Oxidative Stress and DNA Methylation in Prostate Cancer by Krishna Vanaja Donkena, Charles Y. F. Young, Donald J. Tindall

“…An imbalance in the oxidative stress/antioxidant status is observed in prostate cancer patients. Genome oxidative damage in prostate cancer patients is associated with higher lipid peroxidation and lower antioxidant levels. …”
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Science et développement : l’action de François Gros au COPED by Auger, Pierre, Delseny, Michel

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Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases by Sudha Sharma

“…Increasing evidence suggests that genomic instabilities induced by non-B DNA secondary structures result in predisposition to diseases. …”
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Monkeypox and other orthopoxvirus zoonoses by K. N. Gruzdev

“…Scientists are alarmed by these facts as the camelpox virus genomeis 99% homologous to the genome of the small poxvirus. This requires strengthening the epizootological and epidemiological monitoring of orthopoxvirus zoonotic pathogens.…”
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Genetic Diversity Analysis of Mulberry Silkworm (Bombyx Mori L.) Hybrids and Breeds in Azerbaijan Using RAPD Markers by Mammadov Ayaz, Aghayeva Saltanat, Bakırov Guduret, Gulubeyova Mahpuba, Ismayılova Gular

“…For this purpose, silkworm larvae were taken for DNA extraction and nuclear genome DNA was isolated from various parts of the silkworm (silk gland, epidermis, etc.). …”
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Metabolic Analysis of the Mode of Action and Mode of Resistance for Novobiocin in Staphylococcus aureus by Weile Xie, Dan Luo, Zhe Wang

“…Further metabolomic analysis revealed the function of the major mutation (in gyrB) in relation to the potential mechanism through which S. aureus responds to novobiocin. Through whole genome sequencing, three mutations of S. aureus in gyrB, potB, and fpgS were identified. …”
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Prevalence, Molecular Epidemiology, and Clinical Characteristics of Human Bocavirus Among Patients with Acute Gastroenteritis in Northern Brazil During 2017–2022 by Yasmim Gabrielly Souza Sousa, Carolina Alcântara Maneschy, Carolina Costa Monteiro, João Victor Souza Rodrigues, Patrícia Santos Lobo, Dielle Monteiro Teixeira, Jones Anderson Monteiro Siqueira, Kenny Costa Pinheiro, Hugo Reis Resque, Luciana Damascena Silva, Sylvia Fátima dos Santos Guerra, Luana Silva Soares

“…Fecal suspensions (20%) were prepared, and the viral genome was extracted. PCR and nested-PCR were employed to detect HBoV, followed by nucleotide sequencing to identify viral types. …”
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A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins by Xiuxiu Lu, Monika Chandravanshi, Venkata R. Sabbasani, Snehal Gaikwad, V. Keith Hughitt, Nana Gyabaah-Kessie, Bradley T. Scroggins, Sudipto Das, Wazo Myint, Michelle E. Clapp, Charles D. Schwieters, Marzena A. Dyba, Derek L. Bolhuis, Janusz W. Koscielniak, Thorkell Andresson, Michael J. Emanuele, Nicholas G. Brown, Hiroshi Matsuo, Raj Chari, Deborah E. Citrin, Beverly A. Mock, Rolf E. Swenson, Kylie J. Walters

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Identification of the Granule-Bound Starch Synthase (GBSS) Genes Involved in Amylose Biosynthesis in Tartary Buckwheat (<i>Fagopyrum tataricum</i> (L.) Gaertn.) by Juan Huang, Fei Liu, Jieqiong Zhang, Bin Tang, Jiao Deng, Taoxiong Shi, Liwei Zhu, Hongyou Li, Qingfu Chen

“…Although one has already been cloned, the <i>GBSS</i> genes at the genome-wide level have not yet been fully assessed and thoroughly analyzed in Tartary buckwheat. …”
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Transcriptome Analysis of <i>Stephania yunnanensis</i> and Functional Validation of CYP80s Involved in Benzylisoquinoline Alkaloid Biosynthesis by Wenlong Shi, Qishuang Li, Xinyi Li, Linglong Luo, Jingyi Gan, Ying Ma, Jian Wang, Tong Chen, Yifeng Zhang, Ping Su, Xiaohui Ma, Juan Guo, Luqi Huang

“…Previous research reported the genome of <i>S. yunnanensis</i> and preliminarily identified the norcoclaurine synthase (NCS), which is involved in the early stages of the BIA biosynthetic pathways. …”
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A prognostic model of 8-T/B cell receptor-related signatures for hepatocellular carcinoma by Xuan Zuo, Hui Li, Shi Xie, Mengfen Shi, Yujuan Guan, Huiyuan Liu, Rong Yan, Anqi Zheng, Xueying Li, Jiabang Liu, Yifan Gan, Haiyan Shi, Keng Chen, Shijie Jia, Guanmei Chen, Min Liao, Zhanhui Wang, Yanyan Han, Baolin Liao

“…Methods In this study, we categorized gene expression data of HCC patients from The Cancer Genome Altas and identified TCR related genes by the Least Absolute Shrinkage and Selection Operator and multivariate Cox regression analysis. …”
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Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

“…NMM exhibited a minimum inhibitory concentration (MIC) of 5 μM against S. aureus USA300, impacting cell division and the cell wall by repressing the expressions of genes in the division cell wall (dcw) gene cluster. Genome-wide bioinformatics analysis of G4 motifs and their mapping on S. aureus genome, identified the presence of G4-motif in the promoter of mraZ, a conserved master regulator of the dcw cluster regulating the coordinated cell division and cell wall synthesis. …”
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Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma by Hengchang Liu, Jialiang Liu, Xu Guan, Zhixun Zhao, Pu Cheng, Haipeng Chen, Zheng Jiang, Xishan Wang

“…Methods Data on gene expression and mutations in READ were obtained from The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) databases. …”
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Shared genetic risk and causal associations between Post-traumatic stress disorder and migraine with antithrombotic agents and other medications by Charlotte K. Bainomugisa, Dagmar Bruenig, Heidi G. Sutherland, Lyn R. Griffiths, Dale R. Nyholt, Divya Mehta

“…There are proposed biological, genetic and environmental factors associated with both PTSD and migraine suggesting shared etiology. Genome-Wide Association Studies (GWAS) have been used to identify genomic risk loci associated with various disorders and to investigate genetic overlap between traits. …”
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ATP1B3 may promote glioma proliferation and migration through MAPK/NF-KB signaling pathway by Qikang Yan, Quan Sun, Yan Feng, Qingyun Hu, Jinling Zhu

“…ObjectiveTo investigate the function of ATPase Na+/K+ Transporting Subunit Beta 3 (ATP1B3) in gliomas and the molecular mechanisms associated with them in order to identify a novel target and approach for glioma clinical diagnosis and treatment.MethodsThe Cancer Genome Atlas (TCGA), a public tumor database, and the Chinese Glioma Genome Atlas (CGGA) were used to evaluate the differential expression of ATP1B3 in glioma cells of various grades. …”
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Advances in auxin synthesis, transport, and signaling in rice: implications for stress resilience and crop improvement by Mengmeng Hou, Yuanbo Zhang, Xinyi Xu, Hao Ai

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Correlation between Ferroptosis-Related Gene Signature and Immune Landscape, Prognosis in Breast Cancer by Jiahao Zhu, Qingqing Chen, Ke Gu, You Meng, Shengjun Ji, Yutian Zhao, Bo Yang

“…FRG expression profiles and clinical data were downloaded from The Cancer Genome Atlas (TCGA) database and Gene Expression Omnibus (GEO). …”
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Nutrigenomics: Definitions and Advances of This New Science by N. M. R. Sales, P. B. Pelegrini, M. C. Goersch

“…With the advance of science, especially after the conclusion of the Human Genome Project (HGP), scientists started questioning if the interaction between genes and food bioactive compounds could positively or negatively influence an individual’s health. …”
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Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets by Giovanna Morello, Antonio Gianmaria Spampinato, Sebastiano Cavallaro

“…Our research group recently described genome-wide characterization of motor cortex samples from sporadic ALS (SALS) patients, revealing the existence of molecular and functional heterogeneity in SALS. …”
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A CACTA-like transposon in the Anthocyanidin synthase 1 (Ans-1) gene is responsible for apricot fruit colour in the raspberry (Rubus idaeus) cultivar 'Varnes'. by Daniel James Sargent, Matteo Buti, Stefan Martens, Claudio Pugliesi, Kjersti Aaby, Dag Røen, Chandra Bhan Yadav, Felicidad Fernández Fernández, Muath Alsheikh, Jahn Davik, R Jordan Price

“…By performing RNASeq, we revealed differential expression patterns in the apricot-fruited 'Varnes' for genes in the anthocyanin biosynthesis pathway and following whole genome sequencing using long-read Oxford Nanopore Technologies sequencing, we identified a CACTA-like transposable element (TE) in the second exon of the Anthocyanidin synthase (Ans) gene that caused a truncated predicted ANS protein. …”
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