11p15.4 Microdeletion Associates with Hemihypertrophy by Surasak Puvabanditsin, Mehrin Sadiq, Marianne Jacob, Maaz Jalil, Kenya Cabrera, Omer Choudry, Rajeev Mehta

“…The results of whole genome SNP microarray analysis showed approximately 77 Kb interstitial deletion of the short arm of chromosome 11 (11p15.4). …”
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Correction: Integrating E-cadherin expression levels with TNM staging for enhanced prognostic prediction in colorectal cancer patients by Jae-Ghi Lee, Ilkyu Park, Hannah Lee, Seungyoon Nam, Jisup Kim, Won-Suk Lee, Myunghee Kang, Jung Ho Kim

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Advances in lignocellulosic feedstocks for bioenergy and bioproducts by Daniel B. Sulis, Nathalie Lavoine, Heike Sederoff, Xiao Jiang, Barbara M. Marques, Kai Lan, Carlos Cofre-Vega, Rodolphe Barrangou, Jack P. Wang

“…It also explores emerging biotechnologies such as CRISPR-based genome editing informed by machine learning, aimed at improving feedstock traits and reducing the environmental impact of fossil fuel dependence.…”
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Genital Abnormalities and Growth Retardation as Early Signs of Dilated Cardiomyopathy with Ataxia Syndrome by Kyriaki Papadopoulou-Legbelou, Maria Ntoumpara, Maria Kavga, Eleni P. Kotanidou, Ioannis Papoulidis, Assimina Galli-Tsinopoulou, Maria Fotoulaki

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MOLECULAR MARKERS: IMPLEMENTATION IN CROP PLANT BREEDING FOR IDENTIFICATION, INTROGRESSION, AND GENE PYRAMIDING by I. N. Leonova

“…To date, the main practical application of molecular markers is related to germplasm characterization, introgression and pyramiding of genome fragments associated with agronomically important traits controlled by major genes. …”
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Towards Multitarget Testing in Molecular Microbiology by Deborah Steensels, Anne Vankeerberghen, Hans De Beenhouwer

“…They are particularly useful when patient treatment has already been initiated or for specimens that may contain microorganisms that are slow-growing, difficult to culture, or for which culture methods do not exist. However, due to genome variability, single target testing might lead to false-negative results. …”
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HighDimMixedModels.jl: Robust high-dimensional mixed-effects models across omics data. by Evan Gorstein, Rosa Aghdam, Claudia Solís-Lemus

“…Here, we empirically study the behavior of this algorithm on simulated and real examples of three types of data that are common in modern biology: transcriptome, genome-wide association, and microbiome data. Our simulations provide new insights into the algorithm's behavior in these settings, and, comparing the performance of two popular penalties, we demonstrate that the smoothly clipped absolute deviation (SCAD) penalty consistently outperforms the least absolute shrinkage and selection operator (LASSO) penalty in terms of both variable selection and estimation accuracy across omics data. …”
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INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES by E. Blum Hubert

“…Based on modern molecular, genetic, epigenetic microbiologic and biochemical studies it is, on the one hand, possible to identify disease-related point mutations and single nucleotide polymorphisms within genome-wide association analyses (GWAS). On the other hand, high throughput array and other technologies made it possible to simultaneously analyze thousands of genes (DNA) or gene products (RNA and proteins), resulting in an individual gene or gene expression profile (‘signature’) or to characterize the individual microbiome and its pathogenetic potential. …”
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Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions by Nadia Martinez-Martin

“…Further development and application of technologies for genome-wide identification of extracellular protein interactions will be important in deciphering functional host-pathogen interaction networks, laying the foundation for development of novel therapeutics.…”
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Colistin Resistance and Management of Drug Resistant Infections by Juhi Sharma, Divakar Sharma, Amit Singh, Kumari Sunita

“…Researchers focus on the most advanced genomics (whole genome sequencing), proteomics, and bioinformatics approaches to explore the question of colistin resistance. …”
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Methylated RNA Immunoprecipitation Sequencing Reveals the m6A Landscape in Oral Squamous Cell Carcinoma by Xi Wang, Jie Wu, Leyu Zhang, Wei Zhao, Jiayin Deng

“…The m6A peaks are always distributed in the junction of the 3′-untranslated regions (3′-UTRs) and the coding sequences (CDS) of mRNAs, as well as the entire genome of long noncoding RNA (lncRNA). Furthermore, enrichment analysis showed that differentially methylated genes were significantly enriched in NF-kappa B signaling pathway, Hedgehog signaling pathway, etc. …”
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Psychrophilic Enzymes: From Folding to Function and Biotechnology by Georges Feller

“…Psychrophiles thriving permanently at near-zero temperatures synthesize cold-active enzymes to sustain their cell cycle. Genome sequences, proteomic, and transcriptomic studies suggest various adaptive features to maintain adequate translation and proper protein folding under cold conditions. …”
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Protocol for in vivo chromatin immunoprecipitation on purified chromatin isolated from mouse liver nuclei by Lei Li, May G. Akl, Scott B. Widenmaier

“…Summary: Chromatin immunoprecipitation (ChIP) is used to investigate genome binding by transcription factors, but it can be problematic. …”
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COMPOSITION AND UTILIZATION OF THE APPLE- TREE COLLECTION IN BELARUS by Z. A. Kazlouskaya

“…Using molecular markers made it possible to identify large-fruit donors with 2-3 oligogenes of apple scab resistance in the same genome, and small-fruit donors with 1-3 oligogenes of powdery mildew resistance. …”
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A Group Feature Screening Procedure Based on Pearson Chi-Square Statistic for Biology Data with Categorical Response by Hanji He, Jianfeng He, Guangming Deng

“…Specifically, group structure exists for biogenetic data, so we need to analyze the entire genome rather than individual strongly correlated genes. …”
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Microbes from Peat Swamp Forest — The Hidden Reservoir for Secondary Metabolites? by Kuan-Shion Ong, Vengadesh Letchumanan, Jodi Woan-Fei Law, Catherine M. Yule, Sui-Mae Lee

“…The interactions observed are attributed to their genomes and to their production of secondary metabolites including antimicrobials. …”
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Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В by M. A. Volkova, P. S. Yaroslavtseva, V. Yu. Sosi Pato Rova, T. L. Eroshina, I. A. Chvala

“…Using real-time RT-PCR avian metapneumovirus genome was detected in the upper part of the respiratory tract, infraorbital sinuses and Harderian gland within 2-12 days post infection. …”
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A Novel Partial Sequence Alignment Tool for Finding Large Deletions by Taner Aruk, Duran Ustek, Olcay Kursun

“…Finding large deletions in genome sequences has become increasingly more useful in bioinformatics, such as in clinical research and diagnosis. …”
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Template switching during DNA replication is a prevalent source of adaptive gene amplification by Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham

“…Copy number variants (CNVs) are an important source of genetic variation underlying rapid adaptation and genome evolution. Whereas point mutation rates vary with genomic location and local DNA features, the role of genome architecture in the formation and evolutionary dynamics of CNVs is poorly understood. …”
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Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening by Wei Jin, Yexuan Deng, John E. La Marca, Emily J. Lelliott, Sarah T. Diepstraten, Christina König, Lin Tai, Valentina Snetkova, Kristel M. Dorighi, Luke Hoberecht, Millicent G. Hedditch, Lauren Whelan, Geraldine Healey, Dan Fayle, Kieran Lau, Margaret A. Potts, Moore Z. Chen, Angus P. R. Johnston, Yang Liao, Wei Shi, Andrew J. Kueh, Benjamin Haley, Jean-Philippe Fortin, Marco J. Herold

“…Our enAsCas12a mouse and accompanying crRNA libraries enhance genome engineering capabilities and complement current CRISPR technologies.…”
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