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2261
Plant diversity and transcriptional variability assessed by retrotransposon-based molecular markers
Published 2017-03-01“…The retrotransposons comprise most of large genomes among plants; differences in their prevalence explain most of the variation in genome size. …”
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2262
Generation and analysis of mouse embryonic stem cells with knockout of the <i>Mcph1</i> (microcephalin) gene
Published 2024-09-01“…Chromatin is not randomly distributed within the nucleus, but organized in a three-dimensional structure that plays a critical role in genome functions. Сohesin and condensins are conserved multi-subunit protein complexes that participate in mammalian genome organization by extruding chromatin loops. …”
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2263
Comparative testing of vaccines based on viruses of genetic lineages G1 and Y280 for their potency against low pathogenic avian influenza H9N2
Published 2021-08-01“…The level of inhibition (reduction) of the virulent LPAI virus genome synthesis in vaccinated birds following their challenge with H9N2 virus of genetic lineage G1 was higher in birds following homologous vaccination, while the time periods of the genome detection in the biomaterial samples were the same. …”
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2264
Engineering a live-attenuated porcine reproductive and respiratory syndrome virus vaccine to prevent RNA recombination by rewiring transcriptional regulatory sequences
Published 2025-02-01“…Reverse genetic manipulation to engineer a different transcriptional regulatory sequence (TRS) circuit introduces genetic traps into the viral genome that are lethal to recombinant RNA progeny viruses. …”
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2265
Current status of recombinant duck enteritis virus vector vaccine research
Published 2025-02-01“…Like other herpesviruses, it has a large genome with multiple non-coding and non-essential regions for viral replication. …”
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2266
Microbiome and Colorectal Cancer in Humans: A Review of Recent Studies
Published 2025-01-01“…In recent years, metagenomic techniques such as shotgun sequencing and genome-wide association studies focused on understanding the role of the microbiota and the metabolome on early CRCs and colon carcinogenesis to determine if there are modifiable or intervenable targets for CRC. …”
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2267
The distribution of allele frequencies of the 15 Short Tandem Repeats loci in Elazığ population, Turkiye
Published 2024-04-01“…The DNA within the Human Genome involves loci with high polymorphism such as short tandem repeats (STR). …”
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2268
The extremely halotolerant black yeast Hortaea werneckii - a model for intraspecific hybridization in clonal fungi
Published 2019-07-01“…The use of these genes was hampered by ambiguous sequences obtained by Sanger sequencing, as a consequence of the diploid and highly heterozygous genome of many H. werneckii strains. Analysis of the BTB and MCM7 genes showed that in some cases two copies of the gene from the same genome are positioned in distant phylogenetic clusters of the intraspecific gene tree. …”
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2269
Tell me y: anticipation of sex discrepancies in cell-free DNA testing due to maternal genetic abnormalities: a case report
Published 2025-01-01“…Amplification of these regions in the DNA isolated from the white blood cells fraction confirmed the presence of Y-chromosome insertions in the maternal genome. This study highlights a new source of discrepancy in cfDNA testing due to maternal genomic variations. …”
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2271
Transcriptome and DNA methylation analysis of the goat pineal gland during puberty
Published 2025-01-01“…To screen pineal gland candidate genes related to the onset of goat puberty and regulated by genome methylation, we collected pineal glands from prepubertal and pubertal female goats, then, determined the DNA methylation profile by whole genome bisulfite sequencing and the transcriptome by RNA sequencing on Illumina HiSeqTM2500. …”
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2272
Development and characterization of a line with substitution of chromosome 4B of wheat <i>Triticum aestivum</i> L. on chromosome 4H<sup><i>mar</i> </sup> of wild barley <i>Hordeum...
Published 2023-11-01“…For this purpose, we crossed the line of bread wheat variety Pyrotrix 28 with an incomplete amphiploid, and then selected cytogenetically stable 42chromosome plants with a high level of fertility in hybrid progeny. Genomic in situ hybridization (GISH) revealed a pair of H. marinum chromosomes in the genome of these plants. …”
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2273
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MsDpo4—a DinB Homolog from Mycobacterium smegmatis—Is an Error-Prone DNA Polymerase That Can Promote G:T and T:G Mismatches
Published 2012-01-01“…Error-prone DNA synthesis in prokaryotes imparts plasticity to the genome to allow for evolution in unfavorable environmental conditions, and this phenomenon is termed adaptive mutagenesis. …”
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Cashmere cyclic growth affected by different photoperiods alters DNA methylation patterns
Published 2024-12-01“…Whole-genome bisulfite sequencing was used to study epigenetic differences in hair follicles from Inner Mongolia Albas cashmere goats during long and short photoperiods. …”
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2278
Functional and Practical Insights Into the Genetic Basis of Takayasu Arteritis
Published 2025-01-01“…Large‐scale genetic studies have significantly contributed to the identification of genetic variation associated with immune‐mediated diseases. To date, five genome‐wide association studies (GWAS) have been performed in TAK, identifying multiple genetic susceptibility loci across the genome. …”
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2279
Interspecific hybridization and cell engineering of lettuce (<i>Lactuca</i> L.)
Published 2024-10-01“…This technique faces problems associated with complicated protoplast regeneration and the loss of reproductive ability in hybrids. Genome-editing methods are more effective and better controllable, but society is still wary of any interference with the plant genome and legally regulates the sale of GM products as food. …”
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2280
Are You My Host? An Overview of Methods Used to Link Bacteriophages with Hosts
Published 2025-01-01“…These include methods to show phage genome entry into host cells (e.g., PhageFISH); proximity of phage and host genomes (e.g., proximity ligation, polonies, viral tagging); and analysis of genomes and metagenomes (e.g., CRISPR spacer analysis, metagenomic co-occurrence). …”
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