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2221
Moving “Forward” in Plasmodium Genetics through a Transposon-Based Approach
Published 2012-01-01“…The genome sequence of the human malaria parasite, Plasmodium falciparum, was released almost a decade ago. …”
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2222
Replication timing in Drosophila and its peculiarities in polytene chromosomes
Published 2019-03-01“…High-throughput methods allowed analysis of DNA replication on a genome scale, as well as its correlation with chromatin structure and gene activi ty. …”
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2223
Prospects for mineral biofortification of wheat: classical breeding and agronomy
Published 2024-09-01“…Despite the promise of transgenesis and genome editing, these labor-intensive methods require significant investments, so these technologies, when applied to wheat, are still at the development stage and cannot be applied routinely. …”
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2224
Human microbiome, applied to clinical practice
Published 2018-08-01“…The Human microbiome project was designed for identification and characterization of set of human microorganisms as well as for studying the changes in the human health due to microbiome changes. The Human Genome Project assumes: development of the human genome variations database (HapMap; Human Variome Project), interpretation of human phenotype differences (Encyclopedia Of DNA Elements), modeling of human phenomenon (RECON), interpretation of epigenetic variants and hereditary changes in phenotypical manifestations. …”
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2225
Evaluation of Recombinant Antibody Production Efficiency in CHO Cells with Sleeping Beauty Transposon Vector System
Published 2024-09-01“…Different transfection systems are employed for the integration of the target gene cassette into the cell genome and have limitations, such as (i) the integration region in the genome, (ii) the size of the target cassette, and (iii) long selection periods for stable expression. …”
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2226
Chromosome distribution of four LTR retrotransposons and 18 S rDNA in coffea eugenioides
Published 2025-01-01“…Understanding the genomic organization and dynamics of the repeatome is fundamental to enlighten their role in plant genome evolution. …”
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2227
Integrative multi-omics analysis reveals the translational landscape of the plant-parasitic nematode Meloidogyne incognita
Published 2025-01-01“…Our findings revealed numerous previously unannotated translation events and refined the genome annotation. By investigating the genome-wide translational dynamics of M. incognita during parasitism, we revealed that the genes of M. incognita undergo parasitic stage-specific regulation at the translational level. …”
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2228
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2229
The landscape of nucleotide diversity in Drosophila melanogaster is shaped by mutation rate variation
Published 2023-04-01“…What shapes the distribution of nucleotide diversity along the genome? Attempts to answer this question have sparked debate about the roles of neutral stochastic processes and natural selection in molecular evolution. …”
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2230
Innovations in intestinal organoid technology featuring an open apical surface
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2231
Pea (Pisum sativum L.): the uneasy fate of the first genetical object
Published 2015-07-01“…Meanwhile, we await the completion of pea nuclear genome sequencing in 2016. For working out new molecular markers in pea, the synteny of its genome to the sequenced genome of Medicago truncatula is extensively used. …”
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2232
TopoQual polishes circular consensus sequencing data and accurately predicts quality scores
Published 2025-01-01“…Abstract Background Pacific Biosciences (PacBio) circular consensus sequencing (CCS), also known as high fidelity (HiFi) technology, has revolutionized modern genomics by producing long (10 + kb) and highly accurate reads. …”
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2233
Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching ho...
Published 2025-01-01“…We identified bacterial isolates, collected clinical data, and performed antimicrobial susceptibility testing. Genome characteristics of isolates were investigated by whole genome sequencing. …”
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2234
Network-assisted target identification for haploinsufficiency and homozygous profiling screens.
Published 2017-06-01“…Chemical genomic screens have recently emerged as a systematic approach to drug discovery on a genome-wide scale. …”
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2235
Alternative Splicing in Self-Renewal of Embryonic Stem Cells
Published 2011-01-01“…Progressing beyond the limitations of a fixed genomic sequence, alternative splicing offers an additional layer of complexity to produce protein variants that may differ in function and localization that can direct embryonic stem cells to specific differentiation pathways. …”
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2236
Determination of the copy numbers of type A porcine endogenous retroviruses in domestic pigs and wild boars
Published 2017-02-01“…Thus, the Siberian minipig genome has a considerable number of type A PERVs, conceivably pathogenic to humans. …”
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2237
FishPi: a bioinformatic prediction tool to link piRNA and transposable elements
Published 2025-01-01“…Through complementary seed region binding with transposable elements (TEs), piRNAs protect the genome from transposition. A tool to link piRNAs with complementary TE targets will improve our understanding of the role of piRNAs in genome maintenance and gene regulation. …”
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2238
A Survey of SNP Data Analysis
Published 2018-09-01“…Finally, we discuss the future directions of SNP data analysis for genome-wide association.…”
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2239
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2240
Assessment of drought resistance in sorghum CMS lines based on various sterility sources
Published 2021-12-01“…In isonuclear CMS lines, the greatest effect on drought resistance was shown by cytoplasm A3 versus A4 (with the Zheltozernoe 10 genome), cytoplasm A5 versus A1 (with the Karlik 4v genome), and M35-1A versus the analog on cytoplasm 9E (with the Pischevoe 614 genome).Conclusion. …”
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