Identification of Novel GCK and HNF4α Gene Variants in Japanese Pediatric Patients with Onset of Diabetes before 17 Years of Age by Rumi Katashima, Mari Matsumoto, Yuka Watanabe, Maki Moritani, Ichiro Yokota

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PIN2-mediated self-organizing transient auxin flow contributes to auxin maxima at the tip of Arabidopsis cotyledons by Patricio Pérez-Henríquez, Shingo Nagawa, Zhongchi Liu, Xue Pan, Marta Michniewicz, Wenxin Tang, Carolyn Rasmussen, Xinping Cui, Jaimie Van Norman, Lucia Strader, Zhenbiao Yang

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Machine learning assisted composition design of high-entropy Pb-free relaxors with giant energy-storage by Xingcheng Wang, Ji Zhang, Xingshuai Ma, Huajie Luo, Laijun Liu, Hui Liu, Jun Chen

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Multi-gene precision editing tool using CRISPR-Cas12a/Cpf1 system in Ogataea polymorpha by Senqin Hou, Shibin Yang, Wenqin Bai

“…However, the lack of precise and efficient genome editing tools severely hinders the construction of cell factories. …”
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Auditory Phenotype of a Novel Missense Variant in the CEACAM16 Gene in a Large Russian Family With Autosomal Dominant Nonsyndromic Hearing Loss by Tatiana G. Markova, Natalia N. Alekseeva, Oxana P. Ryzhkova, Olga L. Shatokhina, Anna A. Orlova, Viktoriia V. Zabnenkova, Olga S. Groznova, Olesya V. Sagaydak, Svetlana S. Chibisova, Alexander V. Polyakov, George A. Tavartkiladze

“…Genetic testing was performed, including whole-genome sequencing for the proband’s son and Sanger sequence analysis for the proband and for all available family members. …”
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Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain by Darine Villela, Claudia K. Suemoto, Renata Leite, Carlos Augusto Pasqualucci, Lea T. Grinberg, Peter Pearson, Carla Rosenberg

“…Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). …”
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A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer’s Disease by Jorge I. Vélez, Dora Rivera, Claudio A. Mastronardi, Hardip R. Patel, Carlos Tobón, Andrés Villegas, Yeping Cai, Simon Easteal, Francisco Lopera, Mauricio Arcos-Burgos

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First-principles investigation of adhesion strength and interfacial bonding in Mg/X (X = Ti, Zr, Hf, V, Nd, Cr, Mo, Mn, and Fe) interface by Longke Bao, Zhifu Yao, Yuhui Zhang, Cuiping Wang, Kaihong Zheng, Rongpei Shi, Xingjun Liu, Fusheng Pan

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Approaches to Analyze Protein Interactions by Stanley Fields, Becky Drees, Tony R. Hazbun, Chandra Tucker, Amy Hin Yan Tong, Marie Evangelista, Charles Boone, Giuliano Nardelli, Luisa Castagnoli, Adriana Zucconi, Gianni Cesareni, Gary Bader, Chris Hogue

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Efficacy of melatonin treatment in a cystic fibrosis mouse model of airway infection by Kristen R. Schaefer, Sara Rogers, Zachary Faber, Thomas J. Kelley

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All Roads Lead to Rome: Pathways to Engineering Disease Resistance in Plants by Aziz Ul Ikram, Muhammad Saad Shoaib Khan, Faisal Islam, Sulaiman Ahmed, Tengfang Ling, Feng Feng, Zongtao Sun, Huan Chen, Jian Chen

“…Recent developments in genetic engineering, including efficient gene manipulation and transformation methods, gene editing and synthetic biology, coupled with the understanding of microbial pathogenicity and plant immunity, both at molecular and genomic levels, have enhanced the capabilities to develop disease resistance in plants. …”
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Efficiency of Polyphenol Extraction from Artificial Honey Using C18 Cartridges and Amberlite® XAD-2 Resin: A Comparative Study by Chua Yung An, Md. Murad Hossain, Fahmida Alam, Md. Asiful Islam, Md. Ibrahim Khalil, Nadia Alam, Siew Hua Gan

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Intratumor heterogeneity of HPV integration in HPV-associated head and neck cancer by Noah Sasa, Toshihiro Kishikawa, Masashi Mori, Rie Ito, Yumie Mizoro, Masami Suzuki, Hirotaka Eguchi, Hidenori Tanaka, Takahito Fukusumi, Motoyuki Suzuki, Yukinori Takenaka, Keisuke Nimura, Yukinori Okada, Hidenori Inohara

“…Whole-genome sequencing of 51 tumors revealed intratumor heterogeneity of HPV integration, with 44% of breakpoints subclonal, and a biased distribution of integration breakpoints across the HPV genome. …”
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Bacterial community assembly of specific pathogen-free neonatal mice by Elizabeth A. Kennedy, James S. Weagley, Andrew H. Kim, Avan Antia, Anna L. DeVeaux, Megan T. Baldridge

“…Short-read shotgun sequencing-based metagenomic profiling of young pups enabled the assembly of metagenome-assembled genomes for strain-level analysis of these pioneer Ligilactobacillus, Streptococcus, and Proteus species. …”
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Bacterial Diversity in Native Heart Valves in Infective Endocarditis by Anna Sinitskaya, Alexander Kostyunin, Maxim Asanov, Maria Khutornaya, Anastasia Klyueva, Alyona Poddubnyak, Alexey Tupikin, Marsel Kabilov, Maxim Sinitsky

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Latitudinal Variation into the Macrofaunal Assemblages Associated to Zostera noltei Seagrass along the Atlantic Coast of Morocco by Oussama Bououarour, Soilam Boutoumit, Reda El Kamcha, Hocein Bazairi

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Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer’s disease by Michael H. Guo, Wan-Ping Lee, Badri Vardarajan, Gerard D. Schellenberg, Jennifer E. Phillips-Cremins

“…Here, we genotype 312,731 polymorphic STR tracts genome-wide using PCR-free whole genome sequencing data from 2981 individuals (1489 AD case and 1492 control individuals). …”
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VEIKIANTIS GENOMAS - VISUMINIS POŽYMIS: DABARTIES ŽVILGSNIS Į GENETIKĄ by Jonas Rubikas

“…Keywords: genome, genomics, DNA microarrays, proteome. …”
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Complete mitogenome characteristics and phylogenetic analysis of traditional Chinese medicinal plant Tinospora sagittata (Oliv.) Gagnep. from the Menispermaceae family by Jing Zhao, Zi-Han Chen, Peng-Cheng Huang, Liu-Wei Chen, Ming-Xian Zhang, Li-Hua Wang, You-Yong Zhu, Jia-Guan Wang, Yu Zhao

“…Although its plastome and nuclear genome had been sequenced, its mitochondrial genome has not been explored, which significantly hampers conservation efforts and further research for this species. …”
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Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures by Kyung Min Kang, Jeoung Eun Lee, Ji Eun Park, Hyunjin Kim, Hee Yeon Jang, Minyeon Go, Dong Ryul Lee, Sung Han Shim

“…In total, 10 hESC lines were analyzed. For each cell line, genomic DNA was extracted from early and late passages of cell cultures. …”
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