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13841
Argonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles
Published 2025-01-01“…These proteins consist of small, single-stranded RNA or DNA and may provide a route for detecting and silencing complementary mobile genetic elements. In this research, we investigated which AGO(s) were involved in Kawasaki disease (KD). …”
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13842
Understanding and reducing delayed dental care for early childhood caries: a structural equation model approach
Published 2025-02-01“…Multi-factor analysis revealed key factors affecting treatment delay, including permanent residence, medical insurance type, oral health habits, reasons for visit, first symptoms, the time of first discovery of oral problems, brushing teeth before bedtime every day, a genetic history of dental caries and the staging of dental caries. …”
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13843
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13844
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13845
Comprehensive characterization of high-risk coding and non-coding single nucleotide polymorphisms of human CXCR4 gene.
Published 2024-01-01“…This comprehensive analysis shed light on the potential functional consequences of genetic variation in the CXCR genes, offering valuable insights into the implications of disease susceptibility and may pave the way for future therapeutic interventions.…”
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13846
A scoping review on the obstacles faced by beta thalassemia major patients in Pakistan- Matter of policy investment
Published 2024-11-01“…Beta-thalassemia major (β-TM) is a genetic disorder, prevalent especially in the Mediterranean region, Southeast Asia, and the Indian subcontinent. …”
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13847
RETRACTED: Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection
Published 2021-10-01“…These bacteria are genetically closely related and share many virulence factors, including adhesins and toxins. …”
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13848
Molecular Characterization and Risk Factors of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolated from Chinese Tertiary Hospital
Published 2025-01-01“…Rongping Zhu,1,* Ju Li,2,* Siyan Lian,2,* Yishan Li,3 Meili Cai,2 Yingping Cao,2 Xiaohong Xu2,4 1Department of Blood Transfusion, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, Fujian, 350001, People’s Republic of China; 2Department of Laboratory Medicine, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, People’s Republic of China; 3Anxi County Traditional Chinese Medicine Hospital, Quanzhou, Fujian, 362000, People’s Republic of China; 4Fujian Medical University Union Clinical College, Fuzhou, Fujian, 350001, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaohong Xu; Yingping Cao, Department of Clinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, People’s Republic of China, Tel +86 13959192290 ; +86 13365910806, Email vancy1988@163.com; caoyingping@aliyun.comBackground: Therefore, the objectives of this study were to investigate the prevalence of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) in Fujian Medical University Union Hospital, identify their genetic characters, characterize their resistance profiles, and identify risk factors for their infection to improve prevention and treatment strategies for CR-hvKp in the area.Methods: Between January 2021 and January 2022, clinically identified carbapenem-resistant Klebsiella pneumoniae (CRKp) isolates were collected. …”
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13849
Naturally occurring influenza reassortment in pigs facilitates the emergence of intrahost virus subpopulations with distinct genotypes and replicative fitness
Published 2025-01-01“…., farm, region, country), limited field research has explored the extent of reassortment happening at the single pig level and how that contributes to the overall genetic and biological variation observed in populations. …”
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13850
Investigation of <i>ITGB3</i> Heterogeneity to Overcome Trastuzumab Resistance in HER2-Positive Breast Cancer
Published 2024-12-01“…Tumour heterogeneity, describing genetic, epigenetic, and phenotypic differences within and between tumours, complicates tumour treatment and contributes to drug resistance. …”
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13851
"Preparation and curing kinetics of “bottlebrush-like structure” green bio-based ultra-low-temperature polyfarnesene nanocomposites"
Published 2024-12-01“…As a versatile monomer, trans-β-farnesene had a special structure of long side chain monosubstitution, which could be genetically edited from the source to form a “bottlebrush-like” polymer with a regular structure. …”
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13852
Comprehensive profiling of gut bacterial communities in hybrid red tilapia with and without streptococcosis
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13853
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13854
Polymorphic Single‐Nucleotide Variants in miRNA Genes and the Susceptibility to Colorectal Cancer: Combined Evaluation by Pairwise and Network Meta‐Analysis, Thakkinstian's Algorit...
Published 2025-01-01“…Network meta‐analysis and the Thakkinstian's method were applied for determining the potentially optimal genetic models; additionally, the FPRP was used to identify noteworthy associations. …”
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13855
Competing sexual-asexual generic names in Agaricomycotina (Basidiomycota) with recommendations for use
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13856
Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization
Published 2025-01-01“…Also, using mammalian cells that exclusively or predominately express IP3R1, to which Bok binds strongly, and a fluorescent Ca2+-sensitive dye or a genetically-encoded Ca2+ sensor, we explored how endogenous and exogenous Bok controls the Ca2+ mobilizing function of IP3R1, and whether Bok phosphorylation at Ser-8, or replacement of Ser-8 with a phosphomimetic amino acid, is regulatory. …”
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13857
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13858
Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes
Published 2025-01-01“…We develop a classifier that can be used to infer chromatin status in single-cell or bulk RNA-seq data, enabling identification of altered chromatin transition in genetic knock-outs, and a quality control to identify skewed NSN-SN proportions that could otherwise confound differential gene expression analysis. …”
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13859
Differential HLA Association of GAD65 and IA2 Autoantibodies in North Indian Type 1 Diabetes Patients
Published 2021-01-01“…We evaluated the prevalence of GAD65 and IA-2 autoantibodies (GADA and IA2A) in 252 T1D patients from North India and investigated the genetic association of GADA and IA2A with HLA class I and class II genes/haplotypes. …”
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13860
Serological, phenotypic and molecular characterization of brucellosis in small ruminants in northern Algeria
Published 2025-01-01“…The phylogenetic analysis and clustering with the West Mediterranean lineage of B. melitensis revealed high genetic similarity of the investigated isolates with B. melitensis of human origin from North Africa and travel-associated ‘European’ cases, especially from Morroco, Tunisia, Sweden and Italy. …”
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