Bayesian joint-regression analysis of unbalanced series of on-farm trials by Turbet Delof, Michel, Rivière, Pierre, Dawson, Julie C, Gauffreteau, Arnaud, Goldringer, Isabelle, van Frank, Gaëlle, David, Olivier

“…The methods developed could be used for evaluation and/or selection within networks of various stakeholders such as farmers, gardeners, plant breeders or managers of genetic resource centres.…”
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Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis by Hongxi Guo, Juan Luo, Hu Yang, Jun Yang, Hongqiang Bian, Xufei Duan, Xin Wang

“…Notably, 41.2% (7 cases) involved genetic and congenital anatomical variations. Pancreatic duct stent placement was successfully performed in all 17 children (100.0% success rate). …”
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Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context by Hui Ying, Xueyan Wu, Xiaojing Jia, Qianqian Yang, Haoyu Liu, Huiling Zhao, Zhihe Chen, Min Xu, Tiange Wang, Mian Li, Zhiyun Zhao, Ruizhi Zheng, Shuangyuan Wang, Hong Lin, Yu Xu, Jieli Lu, Weiqing Wang, Guang Ning, Jie Zheng, Yufang Bi

“…Methods: We conducted a Mendelian randomization (MR) and colocalization analysis using 26,597 single-cell expression quantitative trait loci (sc-eQTL) to proxy effects of expressions of 16,597 genes in 14 peripheral blood immune cells and tested them against four COVID-19 outcomes from COVID-19 Genetic Housing Initiative GWAS meta-analysis Round 7. …”
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Comparative transcriptomic analysis and identification of candidate genes related to Verticillium wilt resistance in Gossypium barbadense and Gossypium hirsutum by Jieyin Zhao, Xingui Hu, Yuxiang Wang, Jiaxin Lu, Wenju Gao, Xuening Su, Quanjia Chen, Yanying Qu

“…In conclusion, our results provide a theoretical basis for an in-depth understanding of the molecular mechanism underlying the difference in Verticillium wilt resistance between G. barbadense and G. hirsutum and provide a new genetic resource for the study of cotton resistance to Verticillium wilt.…”
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Breast cancer risk assessment based on a predictive model: evaluation of risk factors among Japanese women by Michiyo Yamada, Takashi Chishima, Takashi Ishikawa, Kazutaka Narui, Sadatoshi Sugae, Peter J. Tonellato, Itaru Endo

“…Conclusion Our widely available, simple, and cost-effective models with optimal variables could indicate the characteristics of certain genetic and environmental risk factors for BC in Japanese women.…”
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Dissemination of Staphylococcus epidermidis in Swedish bovine dairy herds: minimal overlap with human isolates by Karin Persson Waller, Mattias Myrenås, Hyeyoung Kim, Micael Widerström, Tor Monsen, Stefan Börjesson, Stefan Börjesson, Stefan Börjesson, Emma Östlund, Wonhee Cha

“…The primary aim of this study was to assess the genetic relatedness of S. epidermidis isolates from bovine subclinical mastitis (SCM), bovine milk filters, healthy dairy farmers or farm personnel, and human hospital patients in Sweden, and to detect and compare genes encoding antimicrobial resistance (AMR) and virulence factors. …”
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Influence of minor hydrocarbon seepage on sulfur cycling in marine subsurface sediments by E. Schnabel, A. Vuillemin, C. C. Laczny, B. J. Kunath, A. R. Soares, A. J. Probst, R. Di Primio, J. Kallmeyer

“…</p> <p>Overall, our study demonstrates that the gradient in pore water geochemistry, the rates of sulfate reduction processes, and the genetic features of microbial populations actively involved in sulfate-driven AOM processes are all affected by low and often unnoticed upward HC fluxes. …”
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uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

“…Abstract Background Neuronal intranuclear inclusion disease (NIID) is genetically linked to CGG repeat expansion in the 5’-untranslated region of the NOTCH2NLC gene, with nascent polyglycine-containing protein (uN2CpolyG) identified as a primary pathogenic factor. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…Furthermore, many of these studies lack sufficient clinical follow-up data, making it difficult to draw meaningful associations between genetic variants and patient outcomes. Our study aimed to characterize the mutational landscape of cDLBCL using whole-genome sequencing of matched tumor-normal samples obtained from a cohort of 43 dogs previously enrolled in a clinical trial for which longitudinal follow-up was available. …”
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Embryonic heat conditioning induces paternal heredity of immunological cross- tolerance: coordinative role of CpG DNA methylation and miR-200a regulation by Padma Malini Ravi, Tatiana Kisliouk, Shelly Druyan, Amit Haron, Mark A. Cline, Elizabeth R. Gilbert, Noam Meiri

“…While the initial stress-response set-points in the hypothalamus may be genetically determined, they are further influenced by epigenetic factors during embryonic development. …”
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Advancing the Indian cattle pangenome: characterizing non-reference sequences in Bos indicus by Sarwar Azam, Abhisek Sahu, Naveen Kumar Pandey, Mahesh Neupane, Curtis P Van Tassell, Benjamin D Rosen, Ravi Kumar Gandham, Subha Narayan Rath, Subeer S Majumdar

“…Abstract Background India harbors the world’s largest cattle population, encompassing over 50 distinct Bos indicus breeds. This rich genetic diversity underscores the inadequacy of a single reference genome to fully capture the genomic landscape of Indian cattle. …”
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From the Banks of the Orkhon to the Banks of the Neva: the History of Mining and Transit of Mongolian Gold to the Russian Empire at the beginning of the 20th century. by Aldar A. Shirapov, Anna M. Plekhanova

“…The main method used is historical-genetic, the use of which helped to identify the reasons according to which the Mongolor joint-stock company was created, as well as to reconstruct the mechanism of both gold production by this company and its further transit to Russia. …”
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Riverine microplastic discharge along the southern Black Sea coast of Türkiye by Yahya Terzi, Rafet Çağrı Öztürk, Ahmet Raif Eryaşar, İlhan Yandi, Ahmet Şahin, Fatih Yılmaz, Kenan Gedik, Sedat Gündoğdu

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Optimizing boron application methods and dosages to enhance jute (Corchorus olitorius) seed yield and quality under sub-tropical climate by Tapan Kumar, Pritthee Mallick Tama, Syed Aflatun Kabir Hemel, Ranjit Kumar Ghosh, Md Imran Ali, Abdullah Al-Bakky, Abdul Alim

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Analisis Metode Estimasi Biaya pada Perangkat Lunak Beserta Faktor-Faktor yang Mempengaruhi : A Systematic Literature Review by Amelia Devi Putri Ariyanto, Lutfiyatul ‘Azizah, Umi Laili Yuhana

“…Besides, this study also succeeded in finding the best method and combination of methods based on best accuracy, namely COCOMO II and the combination of Genetic Algorithm and Artificial Bee Colony, along with the five main factors that influence cost estimation so that it can be used by researchers or other practitioners to develop cost estimates for software projects. …”
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FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss by Lijun Li, Renjin Lin, Yang Xu, Lingdi Li, Zhijun Pan, Jian Huang

“…Osteoporosis is a significant global health issue, and the current treatment options are highly restricted. Transplanting genetically engineered MSCs has been acknowledged as a highly promising therapy for osteoporosis. …”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…Its development at patients of all age groups is observed on a background of gastritis with, probably, genetically determined hyperplasia of gastric epithelial cells producing NO-synthase and endothelin-1. …”
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Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro by Han T, Jia T, Wang J

“…Tala Han,1 Ting Jia,1 Junrui Wang1,2 1Department of Laboratory Medicine, Affiliated Hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of China; 2Inner Mongolia Key Laboratory of Clinical Pathogenic Microorganism, The Affiliated Hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of ChinaCorrespondence: Junrui Wang, Clinical Laboratory, Affiliated hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of China, Tel +86 04713451315, Email wangjunrui123@yeah.netBackground: Linezolid resistance in methicillin-resistant Staphylococcus aureus (MRSA) was reported frequently in recent years, but the mechanism underlying this process was less reported, especially for clinical isolates with different genetic background. Thus, this study aims to explore the adaptive evolution characteristics underlying linezolid resistance in MRSA clinical isolates exposed to continuous induction stress of linezolid in vitro.Methods: The in vitro susceptibility of 1032 MRSA clinical isolates to linezolid was detected using commercial VITEK-2 equipment via broth microdilution. …”
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Prediction model for unfavorable treatment outcome for complicated sever acute malnutrition (SAM) in under five children admitted in hospitals at Amhara Region by Almaw Genet Yeshiwas, Zelalem Alamrew Anteneh, Tilahun Degu Tsega, Ahmed Fentaw Ahmed, Chalachew Yenew

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Structural insights into dynamics of the BMV TLS aminoacylation by Wen Yang, Ran Yi, Jing Yao, Yongxiang Gao, Shanshan Li, Qingguo Gong, Kaiming Zhang

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