Current data on the circulation of the Q fever pathogen in the Republic of Guinea by Ekaterina V. Naidenova, Kirill S. Zakharov, Dmitry A. Agafonov, Mikhail Yu. Kartashov, Aislu M. Senichkina, Erik S. Khalilov, Abdoul B. Ibrahim, Mamadou B. Bah, Ibrahim Nourdine, Nikolai K. Tokarevich, Sanaba Boumbaly, Yusuf Sidime, Svetlana A. Shcherbakova, Vladimir V. Kutyrev

“…The study was carried out using ELISA and PCR methods, selected samples were subjected to in-depth genetic analysis. Results and discussion. The study of the distribution of C. burnetii on the territory of all landscape-geographical zones of the Republic of Guinea was carried out. …”
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Clinical analysis of pulmonary mucosa-associated lymphoid tissue lymphoma coexisting with lung cancer by Heng Yang, Man-Hui Li, Qiu-Hong Li, Ke-Bin Cheng, Wei-Jun Cao

“…Methods We retrospectively analyzed the clinical, imaging, genetic mutations and pathological data among adult patients with pulmonary MALT lymphoma coexisting with lung cancer who were confirmed by pathological examinations after operation at Shanghai Pulmonary Hospital between 1st January 2013 and 31st May 2024. …”
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Network Pharmacology and Molecular Docking Study on the Mechanism of the Therapeutic Effect of Strychni Semen in NSCLC by He Geng, Yujie Xue, Binghua Yan, Zhaoxue Lu, Hengjin Yang, Peng Li, Jundong Zhou

“…NSCLC-related targets were retrieved from the GeneCards, OMIM and DisGenet databases. The intersection targets of Strychni Semen in treating NSCLC were obtained via an online platform. …”
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Stage-specific milk yield losses and associated sweating, respiration, and rectal temperature responses under varying temperature-humidity index thresholds in lactating and dry cow... by P.A. Tu, Y.H. Yeh, Y.H. Chen, J.W. Shiau, T.Y. Lin, Thomas Banhazi, M.K. Yang

“…Therefore, comprehensive strategies, including not only cooling measures but also dietary adjustments and genetic improvements for heat tolerance, are required to help these animals regulate their body temperature and avoid HS. …”
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Study on Pore and Fissure Structure Characteristics of Deep Soft Coal Rock by Minbo Zhang, Zhen Zhang, Dangyu Zhang, Delong Zou, Jinlei Du, Zichao Wang, Chunxin Li

“…The results show that there are three major categories and five minor categories of pores with different genetic types, including metamorphic pore, exogenous pore, and mineral pore, and there are endogenous fissures, exogenous tensile fissures, and exogenous shear fissures developed in the coal body. …”
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Evaluation of Human Leukocyte Antigen Class I and Class II in End-Stage Renal Disease Occurrence in Indonesian Transplantation Patients by Hani Susianti, Dwi Priyadi Djatmiko, I Komang Adi Widana, Deasy Ayuningtyas Tandio, Catur Suci Sutrisnani, Singgih Pudjo Wahono, Ira Puspitawati

“…Background. Genetic studies of end-stage renal disease (ESRD), including those of human leukocyte antigen (HLA) genes, have been reported in several populations but have not yet been evaluated in Indonesia. …”
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Integrating Metabolomics and Genomics to Uncover the Impact of Fermented Total Mixed Ration on Heifer Growth Performance Through Host-Dependent Metabolic Pathways by Zhenzhen Hu, Minyu Zuo, Shixuan Ding, Yifan Zhong, Mingyuan Xue, Huichao Zheng

“…With the increasing demand for enhancing livestock production performance and optimizing feed efficiency, this study aimed to investigate the effects of fermented total mixed ration (FTMR) containing different proportions of rice straw and sheath and leaves of <i>Zizania latifolia</i> on systemic nutrient metabolism and oxidative metabolism under host genetic regulation and on growth performance of heifers. …”
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A novel oncolytic Vaccinia virus armed with IL-12 augments antitumor immune responses leading to durable regression in murine models of lung cancer by Lijuan Chen, Lijuan Chen, Pengju Wang, Carmela Di Gioia, Ming Yuan, Zhe Zhang, Jinxin Miao, Wenli Yan, Guanghao Zhao, Yangyang Jia, Na Wang, Zhongxian Zhang, Haoran Guo, Giulia Marelli, Louisa Chard Dunmall, Nicholas R. Lemoine, Nicholas R. Lemoine, Yaohe Wang, Yaohe Wang

“…Here, we investigated the use of VVL-m12, a next-generation, genetically modified, interleukin-12 (IL-12)-armed VV, as a new therapeutic strategy to treat murine models of lung cancer and as a mechanism of increasing lung cancer sensitivity to antibody against programmed cell death protein 1 (α-PD1) therapy. …”
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Miniaturization and characterization of patient derived hepatocellular carcinoma tumor organoid cultures for cancer drug discovery applications by David A. Close, Paul A. Johnston

“…Patient derived tumor organoid (PDTO) models retain the structural, morphological, genetic, and clonal heterogeneity of the original tumors. …”
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Inflammatory markers link triglyceride-glucose index and obesity indicators with adverse cardiovascular events in patients with hypertension: insights from three cohorts by Yanqiu Huang, Yi Zhou, Yadan Xu, Xiaoyu Wang, Ziyi Zhou, Kang Wu, Qiqi Meng, Liao Wang, Yang Yang, Hong Gao, Juan Ji, Xu Jiang, Yang Yang, Lipeng Hao, Hui Wang

“…Inflammation markers like systemic inflammatory response index (SIRI) and C-reactive protein (CRP) partially explained these links, with CRP having a stronger effect. Genetically predicted TyG was also linked to stroke (OR 1.26, 95%CI 1.10–1.45) risk. …”
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QTL Mapping of Traits Associated with Dual Resistance to the African Stem Borer (Busseola fusca) and Spotted Stem Borer (Chilo partellus) in Sorghum (Sorghum bicolor) by Phyllis W. Muturi, Mary Mgonja, Patrick Rubaihayo, James K. Mwololo

“…Insect damage traits and morphological traits were correlated using Pearson’s correlation coefficients. Genetic mapping was done using JoinMap 4 software, while QTL analysis was done using PLABQTL software. …”
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Influence of quartz types on mechanical parameters in the early silurian Longmaxi shale, Sichuan Basin by Qin Zhang, Feng Liang, Qun Zhao, Wen Liu, Weiliang Kong, Wanli Gao, Xinyu Zhang, Guangyin Cai, Tianquan Qu, Zhen Qiu

“…After systematic analysis of organic geochemistry, mineral composition, cathodoluminescence observation, major/trace elements, and log interpretation and calculation of shale mechanical parameters, the genetic mechanism of quartz was analyzed and the percentage of quartz of different origins and the influence on rock mechanical properties were evaluated quantitatively. …”
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A Nomogram Built on Clinical Factors and CT Attenuation Scores for Predicting Treatment Response of Acute Myeloid Leukemia Patients by Linna Liu, Wenzheng Lu, Li Xiong, Han Qi, Robert Peter Gale, Bin Yin

“…While clinical factors such as age and genetic mutations contribute to prognosis, recent studies suggest that CT attenuation scores may also predict treatment outcomes. …”
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Research on leakage and diffusion behavior of hydrogen doped natural gas in integrated pipeline corridors based on data drive by Xiaolong Gong, Hua Li, Cheng Li, Mingyue Kou, Lingxu Kong, Hongcheng Liu

“…In addition, the backpropagation neural network (BPNN) combined with the global optimization capability of genetic algorithm and the nonlinear mapping capability of neural network is used in this paper to provide a reliable technical means for the accurate prediction of explosion risk volume, which has important application value in the safety design of pipeline corridor and accident prevention and control. …”
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Antimicrobial Resistance and Biofilm-Forming Ability in ESBL-Producing and Non-ESBL-Producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Isolated from Canine Urinary... by Alessia Facchin, Joel Filipe, Irene Mauri, Filippo Tagliasacchi, Guido Grilli, Tiziana Vitiello, Gabriele Ratti, Laura Musa, Martina Penati, Paola Scarpa, Stefania Lauzi

“…<b>Methods</b>: The <i>E. coli</i> and <i>K. pneumoniae</i> isolates were bacteriologically and genetically analyzed. <b>Results</b>: Overall, 53/133 (39.8%) samples had a positive microbiological culture. …”
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Pregnancy Outcomes among Patients with Sickle Cell Disease in Brazzaville by F. O. Galiba Atipo Tsiba, C. Itoua, C. Ehourossika, N. Y. Ngakegni, G. Buambo, N. S. B. Potokoue Mpia, A. Elira Dokekias

“…Sickle cell disease (SCD) is one of the most common genetic diseases in the world. It combines, in its homozygous form, chronic hemolytic anemia, vasoocclusive complications, and susceptibility to infections. …”
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Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy by Gregory B. Lesinski, Chrystal M. Paulos, Maggie Phillips, Jacklyn Hammons, Isaac Karpovsky, Zaid Mahdi, Natalie K. Horvat, Megan M. Wyatt, Margaret A. Hall, Cameron J. Herting, Richard A. Moffitt

“…We posit that murine models serve as useful tools to study the fate of T cell therapy. Currently, genetically engineered mouse models (GEMMs) for PDAC are considered a “gold-standard” as they recapitulate many aspects of human disease. …”
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Breast cancer risk assessment based on a predictive model: evaluation of risk factors among Japanese women by Michiyo Yamada, Takashi Chishima, Takashi Ishikawa, Kazutaka Narui, Sadatoshi Sugae, Peter J. Tonellato, Itaru Endo

“…Conclusion Our widely available, simple, and cost-effective models with optimal variables could indicate the characteristics of certain genetic and environmental risk factors for BC in Japanese women.…”
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Mendelian randomization analysis reveals causal relationship between depression, antidepressants and benign paroxysmal vertigo by Yayun Liao, Kejian Zhou, Zhiyan Guo, Lu Qin, Shan Deng, Hong Yang, Baohui Weng, Liya Pan

“…In conclusion, there was a significant causal association between antidepressants and BPV at the genetic level. Clinicians should pay attention to patients with BPV combined with depressive disorders and develop timely interventions.…”
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Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives by Dagmawi Woldesenbet, Yalewayker Tegegne, Abdulhakim Mussema, Elias Tamene, Kemal Mohamed, Wagaw Abebe, Melese Mekuria, Kasahun Bogale, Habtamu Geremew, Mufta Muzemil Shifa, Mulugeta Aemero Tegegne

“…Factors contributing to this resurgence include emerging drug resistance, insecticide resistance, and genetic mutations such as single nucleotide polymorphisms. …”
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