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1341
Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study
Published 2025-02-01“…CIDs develop over the span of several years, and the risk of developing CIDs has been linked to genetic and environmental factors. Thus, modification of environmental factors is a promising approach for the prevention of CIDs. …”
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1342
Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal
Published 2025-02-01“…EEG consistently revealed 2–3.5 Hz generalized spike‐and‐wave discharges. Genetic investigations revealed point mutations and deletions in two cases each. …”
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1343
von Willebrand factor polymorphism (rs1063856) as a risk factor for portal vein thrombosis in chronic liver diseases
Published 2025-02-01“…It is currently unclear how genetic differences in vWF genes relate to the incidence of portal vein thrombosis (PVT). …”
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1344
Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study
Published 2025-02-01“…Exclusion criteria included endocrinological, genetic, or chronic diseases. Untargeted lipidomics analysis was performed using liquid chromatography-mass spectrometry (LC-MS), and serum biomarker levels were measured using ELISA assays. …”
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1345
Hepatic and renal functions of paediatric patients with thalassaemia: a cross-sectional study from two large thalassaemia centres in Sri Lanka
Published 2025-02-01“…Objectives Thalassaemia is a genetic disorder of haemoglobin synthesis characterised by life-long chronic anaemia. …”
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1346
Prevalence and Molecular Characterization of Cysticercus tenuicollis Isolated from Some Intermediate Host in Kurdistan-Iraq
Published 2018-09-01“…The selected cysts were preserved in 70% Ethanol for DNA extraction and molecular study, The mt-CO1 gene was amplified with a conventional polymerase chain reaction (PCR), the PCR product purified and DNA sequencing for reverse and forward strands was determined by a genetic analyzer, the obtained sequences aligned with the DNA sequences of T. hydatigena in Iran, Turkey and Palestine, which deposited in GenBank under the following accession number (JQ710588), (JN827307) and ( KM032284) respectively. …”
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1347
Enhancement of CD8+T cell cytotoxicity activity by IFN-α implies alternative pathologic role in systemic lupus erythematosus
Published 2025-06-01“…Objective: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease which is affected by the environmental, genetic factors as well as the immune system. Previous reports have implicated IFN-α in the pathogenesis of SLE. …”
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1348
Protective potential of structural proteins of the SARS-CoV-2 virus in protecting against COVID-19
Published 2024-12-01“…Recombinant adenoviral vectors rAd5-S, rAd5-N, rAd5-M were used for immunization of animals. Various genetic, virological and immunological methods, as well as methods of working with animals, were used in the study. …”
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1349
Survival and risk factors for metastatic colorectal cancer patients with a history of prior malignancy
Published 2025-02-01“…Therefore, we advocate for active standardized treatment for these patients and propose expanding the range of prior malignancies included in clinical trials based on publication timelines, primary tumour locations, and genetic testing results. The objective is to facilitate timely and proactive treatment for patients following the disclosure of results, thereby instilling confidence in the management of mCRC.…”
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1350
Integration of artificial intelligence and advanced optimization techniques for continuous gas lift under restricted gas supply: A case study
Published 2025-03-01“…To optimize the selected input variables, including tubing inside diameter, gas injection rate, and separator pressure, various optimization algorithms such as particle swarm optimization (PSO), ant colony optimization (ACO), genetic algorithm (GA), and a Novel optimization algorithm in a gas-lift study called grey wolf optimization (GWO), were utilized considering the constraint of the limited available gas. …”
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1351
Factors accounting for limited sexual reproduction in a long-lived unisexual plant species
Published 2025-02-01“…Modelling environmental data at higher resolution, smaller scale and expanding geographic coverage to include more sporophyte occurrences, and comparing genetic diversity in sporophytic with non-sporophytic populations, are future lines of this research.…”
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1352
Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish
Published 2025-01-01“…Collectively, our data shows that IPP exposures can disrupt a battery of biological pathways spanning neurometabolomic, genetic, epigenetic as well as organ-level targets. …”
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1353
Identifying [between] Geser and Genghis Khan. Part 1: Contamination of Images in Folklore and Historical Memories of Central and Inner Asia
Published 2024-09-01“…Methods of comparative analysis ― the comparative/genetic and historical/typological ones ― have proven instrumental in tracing common images and plots of Turko-Mongolian folklore narratives, and considering the latter both within related origins and typological proximities arising from actual historical conditions. …”
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1354
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1355
Bioinformatics screening and clinical validation of CircRNA and related miRNA in male osteoporosis
Published 2025-02-01“…Abstract Background The pathogenesis of male osteoporosis (MOP) remains unclear, with the role of genetic factors attracting the attention of researchers. …”
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1356
Differentiated approach at the choice of chronic hepatitis C antiviral therapy mode (real clinical practice experience)
Published 2018-08-01“…To estimate efficacy and safety of cepeginterferon-alpha 2b (cPEG-IFNα2b) and ribavirin combination for the treatment of chronic hepatitis C (CHC), to define necessity of IL-28V genetic polymorphism diagnostics, to estimate liver elastometry scores at the background of antiviral therapy. …”
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1357
Klasifikasi Kebutuhan Jumlah Produk Makanan Customer Menggunakan K-Means Clustering dengan Optimasi Pusat Awal Cluster Algoritma Genetika
Published 2021-10-01“…This study tries to apply data mining to classify the number of customer needs for food products using k-means clustering with optimization initial cluster center genetic algorithm. In this study used 210 data from product sales for three weeks. …”
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1358
The clinical role of blood coagulation and platelet receptors gene allelic variants in development of Wilson’s disease
Published 2018-08-01“…Original study included 85 patients with a Wilson’s disease who were divided into two groups: without neurological symptoms (abdominal form; n=51) and with neurologic symptomatology (mixed form; n=34). Genetic polymorphism testing was carried out by real-time polymerase chain reaction with melting curve analysis. …”
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1359
Factors Influencing the Pregnancy Outcome of Intrauterine Insemination and Follow-Up Treatment
Published 2023-01-01“…Furthermore, there were 240 couples who not pregnant received one or more cycles of in vitro fertilisation/intracytoplasmic sperm injection/ pre-implantation genetic technology treatment, and another 182 couples forgo follow-up treatment. …”
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1360