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Long-term survival in a large cohort of patients with venous thrombosis: incidence and predictors.
Published 2012-01-01“…<h4>Methods and findings</h4>4,947 patients from the Multiple Environmental and Genetic Assessment study of risk factors for venous thrombosis (MEGA study) with a first nonfatal venous thrombosis or pulmonary embolism and 6,154 control individuals without venous thrombosis, aged 18 to 70 years, were followed up for 8 years. …”
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13564
Family Self-Support in Managing Down Syndrome Children: A Qualitative Study
Published 2024-01-01“…Down syndrome (DS) is the most common reason for disabilities caused by genetic disorders. Due to the special nature of this disease and the special needs of children with Down syndrome, they are required to receive their families’ support. …”
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Phenotypic stability of spring bread wheat regenerant lines
Published 2023-04-01Get full text
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13568
Promising source material for winter triticale breeding under the conditions of the Middle Urals
Published 2022-12-01Get full text
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13569
Physiological and transcriptomic analysis of the effect of overexpression of the NTPIP2;4 gene on drought tolerance in tobacco
Published 2025-01-01“…In this experiment, we constructed an NtPIP2;4 overexpression vector and genetically transformed tobacco variety 'K326' to investigate the mechanism of NtPIP2;4 gene in regulating drought tolerance in tobacco at physiological and transcriptomic levels. …”
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Interleukin-18 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility: An Umbrella Review of Meta-Analyses
Published 2024-01-01“…Data were reanalyzed using Review Manager Software 5.1, and Mantel–Haenszel random effects were applied for the five genetic models: allelic, recessive, dominant, homozygote, and heterozygote. …”
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Immunolipid magnetic bead-based circulating tumor cell sorting: a novel approach for pathological staging of colorectal cancer
Published 2025-01-01“…ObjectiveThis study aimed to assess whether circulating tumor cells (CTCs) from colorectal cancer (CRC) could be used as an alternative to tissue samples for genetic mutation testing, overcoming the challenge of difficult tumor tissue acquisition.MethodsWe developed an immunolipid magnetic bead (IMB) system modified with antibodies against epithelial cell adhesion molecule (EpCAM) and vimentin to efficiently separate CTCs. …”
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Time Series Prediction of COD<sub>Mn</sub> in Dianchi Lake Based on Data Decomposition and NARX Optimization
Published 2024-07-01“…Comparative analyses are made with WPT-particle swarm optimization (PSO) - NARX, WPT-genetic algorithm (GA) - NARX, WPT-NARX, SHIO-NARX, WPT-SHIO extreme learning machine (ELM), and WPT-SHIO-BP neural network models. …”
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A colheita da floresta: Uma estratégia de desenvolvimento social e economicamente viável ao desmatamento?
Published 2010-07-01“…Also, the Biodiversity Convention, which took place during the WCED, highlighted the sovereignty of nations over their biological resources and defined that each country should create its own conditions to facilitate access to genetic resources while promoting the fair and equitable sharing of the benefits derived from the use of such resources.Central to this process are debates over the role of the economic activity in environmental protection, especially the protection of the world’s biodiversity resources upon which the whole economic and climatic systems depend.This paper examines the theory behind some modern development strategies, such as the one that supports that the market economy will save the world’s biodiversity. …”
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Systematic review of bidirectional interaction between gut microbiome, miRNAs, and human pathologies
Published 2025-02-01Get full text
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The production process of spring wheat plants in the system of biological agriculture
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THE STRUCTURE OF THE SIBERIAN GEOGRAPHICAL FLORAL ELEMENT IN THE MIDDLE SIBERIAN FOREST STEPPES
Published 2019-10-01Get full text
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Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies
Published 2025-02-01“…Gene therapy involves altering or manipulating gene expression and can be enhanced by NPs designed to carry various genetic materials. Similarly, NPs can improve the efficacy of ERT for lysosomal storage disorders (LSDs) by facilitating enzyme delivery to the brain, overcoming issues like immunogenicity and instability. …”
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YAP1 as a Novel Negative Biomarker of Immune Checkpoint Inhibitors for EGFR-Mutant Non-Small-Cell Lung Cancer
Published 2023-01-01“…Based on YAP1 expression, all the NSCLC patients including the EGFR-mutant and EGFR-wildtype (WT) patients were divided into two groups, YAP1_High and YAP1_Low. Using cBioPortal, genetic alterations were analyzed for identification of immunogenicity in EGFR-mutant NSCLC. …”
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