State-of-the-art gene therapy for inherited retinal disorders by O.I. Orenburkina, A.E. Babushkin

“…More than 100 IRDs caused by various defects in about 270 genes are known. Molecular genetic diagnostics is essential for identifying a specific hereditary factor of the disease. …”
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Examining the Gm18 and mG Modification Positions in tRNA Sequences by Mayavan Subramanian, Thangavelu Srinivasan, Dorairaj Sudarsanam

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Dependence of the yield in late-generation lines on the spike productivity in original segregating populations of spring bread wheat by S. B. Lepekhov

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Molecular Imaging of Gliomas by A. H. Jacobs, C. Dittmar, A. Winkeler, G. Garlip, W. D. Heiss

“…Third, pathognomonic genetic changes leading to disease have to be explored on the molecular level to serve as specific targets for patient-tailored therapies. …”
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A Few Words about the Hybrid Nature of Mawlid’s Text of the 18th Century by Alla Kozhinowa

“…Regarding Slavonic words, it is difficult to determine their origin accurately due to genetic links of the languages. Definitely, there have been attested lexemes be- longing to Common Slavic, along with Church Slavonic and East Slavonic words of Polish origin. …”
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IL-6 variant is associated with metastasis in breast cancer patients. by Chike O Abana, Brian S Bingham, Ju Hwan Cho, Amy J Graves, Tatsuki Koyama, Robert T Pilarski, A Bapsi Chakravarthy, Fen Xia

“…<h4>Introduction</h4>Although tumor metastases remain significant drivers of mortality, the genetic factors that increase the risks of metastases are not fully identified. …”
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Multiobjective Neuro-Fuzzy Controller Design and Selection of Filter Parameters of UPQC Using Predator Prey Firefly and Enhanced Harmony Search Optimization by Koganti Srilakshmi, Gummadi Srinivasa Rao, Katragadda Swarnasri, Sai Ram Inkollu, Krishnaveni Kondreddi, Praveen Kumar Balachandran, C. Dhanamjayulu, Baseem Khan

“…However, in order to demonstrate the performance of the suggested approach, a comparison is conducted with the ant colony and genetic algorithms, i.e., (ACA) (GA), as well as the standard methods of synchronous reference frame (SRF) and instantaneous active and reactive power theory (p-q). …”
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Development of the adaptive spring bread wheat cultivar ‘Omskaya Yubileynaya’ under the conditions of the Siberian region by N. A. Popolzukhina, P. V. Popolzukhin, A. A. Gaidar, Yu. Yu. Parshutkin, N. A. Yakunina

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Multiobjective Optimization of Surface Roughness and Tool Wear in High-Speed Milling of AA6061 by Machine Learning and NSGA-II by Anh-Tu Nguyen, Van-Hai Nguyen, Tien-Thinh Le, Nhu-Tung Nguyen

“…We applied a two-pronged approach that combines machine learning (ML) and a Nondominated Sorting Genetic Algorithm (NSGA-II) to model and optimize Ra and Vbmax. …”
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Phenotypic variability of <i>Linum usitatissimum</i> L. accessions under the conditions of the Northern Trans-urals by K. P. Korolev, N. A. Bome, N. N. Kolokolova

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RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma by Qiang Xu, Lingyu Kong, Zhezhu Han, Xiuying Jin, Mingyan Ding, Zhengri Piao, Songnan Zhang

“…Methods We assessed the expression properties and genetic alterations of 26 RNA modification writers, including adenosine-to-inosine RNA editing, alternative polyadenylation, m1A, and m6A in 502 lung adenocarcinoma (LUAD) samples from the Cancer Genome Atlas (TCGA) datasets. …”
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Sequential Therapy of Linezolid and Contezolid to Treat Hematogenous Lung Abscess Caused by Staphylococcus aureus in a Congenital Cerebral Hypoplasia Patient: A Case Report by Zhou S, Xin C, Liu W

“…Shuang Zhou,1 Chengqi Xin,2– 5 Wenjuan Liu1 1Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 2Stem Cell Clinical Research Center, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 3National Local Joint Engineering Laboratory, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 4National Genetic Test Center, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China; 5Liaoning Key Laboratory of Frontier Technology of Stem Cell and Precision Medicine, Dalian Innovation Institute of Stem Cell and Precision Medicine, Dalian, Liaoning, People’s Republic of ChinaCorrespondence: Wenjuan Liu; Chengqi Xin, Email liuwenjuan880424@126.com; chengqixin@126.comAbstract: Staphylococcus aureus is a common pathogen of hematogenous lung abscesses. …”
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Efficacy of Topical Mesenchymal Stem Cell Therapy in the Treatment of Experimental Dry Eye Syndrome Model by Emrullah Beyazyıldız, Ferda Alpaslan Pınarlı, Özlem Beyazyıldız, Emine Rümeysa Hekimoğlu, Uğur Acar, Muhammed Necati Demir, Aynur Albayrak, Figen Kaymaz, Güngör Sobacı, Tuncay Delibaşı

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Active Antialopecia Chemical Identification of Merremia peltata Leaves and Computational Study toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation by Syawal Abdurrahman, Ruslin Ruslin, Aliya N. Hasanah, Resmi Mustarichie, Mus Ifaya

“…Alopecia occurs due to various genetic, environmental, and nutritional factors. One of the methods developed to treat alopecia is through inhibition of the enzyme 5-α-reductase, which converts testosterone into its more potent metabolite, dihydrotestosterone (DHT). …”
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The SpxA1-TenA toxin-antitoxin system regulates epigenetic variations of Streptococcus pneumoniae by targeting protein synthesis. by Shaomeng Wang, Xiu-Yuan Li, Mengran Zhu, Haiteng Deng, Juanjuan Wang, Jing-Ren Zhang

“…Because spontaneous variations frequently occur during bacterial growth in the number of the AT di-nucleotides in the promoter region of the spxA1-tenA operon, this locus acts as a programmed genetic switch that generates pneumococcal subpopulations with epigenetic and phenotypic diversity.…”
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Characterization of Integrons and Antimicrobial Resistance in Escherichia coli Sequence Type 131 Isolates by Jiangqing Huang, Fangjun Lan, Yanfang Lu, Bin Li

“…Continued surveillance of this mobile genetic element should be performed to study the evolution of antibiotic resistance among E. coli ST131.…”
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Promoting Immortalized Adipose-Derived Stem Cell Transdifferentiation and Proliferation into Neuronal-Like Cells through Consecutive 525 nm and 825 nm Photobiomodulation by Madeleen Jansen van Rensburg, Anine Crous, Heidi Abrahamse

“…The protein detection of an early neuronal marker, neuron-specific enolase (NSE), and late, ciliary neurotrophic factor (CNTF), was determined with enzyme-linked immunosorbent assays (ELISAs). The genetic expression was also explored through real-time PCR. …”
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RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5. by Julie J Loiselle, Justin G Roy, Leslie C Sutherland

“…Interestingly, the earliest and most frequent genetic alteration associated with lung cancers involves a lesion in the region to which the RNA binding protein RBM5 maps. …”
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Priestia flexa as a Novel Urinary Tract Pathogen in Daloa, Côte d’Ivoire: Insights From Genomic Sequencing by Dého Aristide Gbégbé, Okran Beyosse Christophe Kacou, N’goran Parfait N’zi, Djédoux Maxime Angaman

“…In addition, 438, 350, and 153 mobile genetic elements (MGEs) were predicted in the genomes of strains 21LM367, 21LM1136, and 21LM07, respectively. …”
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A New Mathematical Model for Cell Layout Problem considering Rotation of Unequal Dimensions of Cells and Machines by Raheleh Alamiparvin, Esmaeil Mehdizadeh, Hamed Soleimani

“…In large dimensions, 30 random problems were created, and the results of ICA were compared with the results of the particle swarm optimization (PSO) algorithm and genetic algorithm (GA). Finally, the parameters of the three meta-heuristic algorithms were set by the Taguchi method. …”
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