Role of Ketamine in the Treatment of Psychiatric Disorders by Sahar Derakhshanian, Maxine Zhou, Alexander Rath, Rachel Barlow, Sarah Bertrand, Caroline DeGraw, Christopher Lee, Jamal Hasoon, Alan D. Kaye

“…The illness is complex and combines genetic, pathophysiologic, and environmental factors that combine to negatively affect neurotransmitter balance in the brain. …”
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Pivotal roles of melanopsin containing retinal ganglion cells in pupillary light reflex in photopic conditions by Jeremy Matthew Bohl, Abdul Rhman Hassan, Zachary J. Sharpe, Megi Kola, Angela Shehu, Deborah Langrill Beaudoin, Tomomi Ichinose

“…Previous studies have investigated the roles of photoreceptors and ipRGCs in PLR using genetically-modified mouse models. Herein, we acutely ablated photoreceptors using N-nitroso-N-methylurea (MNU) to examine the roles of ipRGCs in the PLR. …”
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Cerebrospinal fluid metabolites as potential biomarkers for epilepsy: Insights from genome‐wide association studies by Zhenxiang Zhao, Na Xing, Lin Hou

“…Researchers looked at the relationship between 338 cerebrospinal fluid metabolites and 11 types of epilepsy using genetic data. They found that 17 of these chemicals could potentially cause six types of epilepsy. …”
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Glucose-6-phosphate dehydrogenase deficiency with coinherited Gaucher disease: A rare association by Nupur Parakh, Kusha Sharma, Sunita Sharma, Priti Chatterjee, Varinder Singh

“…Similar findings were seen on bone marrow trephine biopsy. Genetic testing revealed pathogenic variations in the GBA gene. …”
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Quality of life and psychological and gastrointestinal symptoms after cholecystectomy: a population-based cohort study by Eivind Ness-Jensen, Kristian Hveem, Stian Lydersen, Arne Talseth, Tom-Harald Edna

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Biosynthesis of ZnO nanoparticles using banana peel pectin for antibacterial and photocatalytic applications by Kazi Suraiya Islam, Md. Hasnain Mustak, Md. Khalid Hossain Shishir, Md. Minnatul Karim, Gazi Md. Arifuzzaman Khan

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Dissemination of Evidence-Based Recommendations for Sickle Cell Disease to Primary Care and Emergency Department Providers in North Carolina: A Cost Benefit Analysis by Paula Tanabe, Audrey L. Blewer, Emily Bonnabeau, Hayden B. Bosworth, Denise H. Clayton, Nancy Crego, Marian F. Earls, Kern Eason, Grayson Forlines, Gary Rains, Matthew Young, Nirmish Shah

“…**Background:** Sickle cell disease (SCD) is a genetic condition affecting primarily individuals of African descent, who happen to be disproportionately impacted by poverty and who lack access to health care. …”
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An untargeted metabolomic analysis of acute AFB1 treatment in liver, breast, and lung cells. by Heidi H Cao, Sabrina Molina, Susan Sumner, Blake R Rushing

“…The mechanism in which AFB1 causes genetic mutations has been well studied, however its metabolomic effects remained largely unknown. …”
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A descriptive-multivariate analysis of community knowledge, confidence, and trust in COVID-19 clinical trials amongst Ugandans working in healthcare settings. by Keneth Iceland, Kasozi, Lawrence Obado, Osuwat

“…Skepticism against DNA recombinant vaccines (DRV) implies genetically modified vaccines such as the Oxford- AstraZeneca vaccine, Pfizer/BioNTech are bound to face a level of resistance once adapted in Uganda. …”
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Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey by Neslihan Bayramoglu Tepe, Reyhan Gunduz, Omer Faruk Dizibuyuk, Huseyin Caglayan Ozcan, Ozge Komurcu Karuserci, Seyhun Sucu, Tanyeli Guneyligil Kazaz, Ali Irfan Kutlar

“…Anomalies that led to termination were grouped as central nervous system , cardiovascular system, gastrointestinal system, genitourinary system, pulmonary, musculoskeletal, head-neck, chromosomal, genetic, multiple anomalies and others. Four groups were formed based on the consistency of prenatal ultrasound diagnosis with pathological diagnosis. …”
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sORFdb – a database for sORFs, small proteins, and small protein families in bacteria by Julian M. Hahnfeld, Oliver Schwengers, Lukas Jelonek, Sonja Diedrich, Franz Cemič, Alexander Goesmann

“…Nonetheless, they represent an essential part of bacteria’s often neglected genetic repertoire. In recent years, the development of ribosome profiling protocols has led to the detection of an increasing number of previously unknown small proteins. …”
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Single-cell immunopathology of recurrent acute generalized exanthematous pustulosis associated with vancomycin by Eric M. Mukherjee, MD, PhD, Andrew Gibson, PhD, Matthew S. Krantz, MD, Rama Gangula, MS, Amy M. Palubinsky, PhD, Alan S. Boyd, MD, Jeffrey P. Zwerner, MD, PhD, Anna K. Dewan, MD, MS, Nontaya Nakkam, PhD, Katherine C. Konvinse, MD, PhD, Yueran Li, PhD, Ramesh Ram, PhD, Abha Chopra, PhD, Elizabeth J. Phillips, MD

“…Objective: To better understand the genetic risk factors and single-cell immunopathogenesis of AGEP, we longitudinally characterized a patient with recurrent AGEP after an initial episode triggered by vancomycin. …”
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Codon usage patterns and genomic variation analysis of chloroplast genomes provides new insights into the evolution of Aroideae by Xinbi Jia, Jiaqi Wei, Yuewen Chen, Chenghong Zeng, Chan Deng, Pengchen Zeng, Yufei Tang, Qinghong Zhou, Yingjin Huang, Qianglong Zhu

“…Our research could provide a theoretical foundation for the chloroplast genetic engineering, taxonomy, and phylogenetic relationships of Aroideae chloroplasts.…”
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Development and evaluation of a recombinant monoclonal human antibody with virus-neutralizing activity against the F glycoprotein of respiratory syncytial virus by Sergey A. Klotchenko, Ekaterina A. Romanovskaya-Romanko, Marina A. Plotnikova, Anastasia A. Pulkina, Aram A. Shaldzhyan, Dmitry S. Balabashin, Victoria A. Toporova, Teimur K. Aliev, Natalia E. Gyulikhandanova, Dmitry A. Lioznov

“…Constructs encoding the recombinant antibody FM1 were designed using genetic engineering. Recombinant antibodies were produced in the CHO-K1 cell line through transient expression. …”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…Mutation of encoding gene — A (TA) 7TAA A is the principal cause of insufficiency of this enzyme, however development of clinical syndrome and severity of symptoms is related to other factors as well (male gender, additional genetic mutations, et al.). Provoking factors of jaundice attacks include fasting, infectious diseases, overstrain, effect of drugs and xenobiotics. …”
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Evaluation of the relatedness between the biofilm-associated genes and antimicrobial resistance among Acinetobacter baumannii isolates in the southwest Iran by Nafiseh Hosseinzadeh Shakib, Zahra Hashemizadeh, Abolfazl Rafati Zomorodi, Reza Khashei, Yeganeh Sadeghi, Abdollah Bazargani

“…The REP-PCR technique was utilized to analyze the genetic relatedness of the isolates (Fig. 4). Results: All isolates displayed multi-drug resistance, with the highest resistance rates observed against ceftazidime, cefotaxime, and trimethoprim/sulfamethoxazole (100%). …”
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Cost-efficient assignment panel for ducks. Setup of a cost-efficient assignment panel for duck populations.  by Chapuis, Hervé, Brard-Fudulea, Sophie, Hazard, Azélie, Vignal, Alain, Demars, Julie, Rouger, Romuald, Teissier, Marc, Gilbert, Hélène

“…This new design impacted the population structure, creating more sire x dam combinations, offering possibilities for a better estimation of non-additive genetic effects, which could prove relevant in the foie gras sector. …”
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Prognostic impact of donor mitochondrial genomic variants in myelodysplastic neoplasms after stem-cell transplantation by Jing Dong, Shahram Arsang-Jang, Tao Zhang, Zhongyuan Chen, Yung-Tsi Bolon, Stephen Spellman, Raul Urrutia, Paul Auer, Wael Saber

“…In the entire donor cohort, we identified 1,825 mtDNA variants, including 67 potential pathogenic variants. Genetic variants on MT-CYB and MT-ND5 genes were identified as independent predictors of posttransplant outcomes. …”
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Whole blood transcriptome profiles of trypanotolerant and trypanosusceptible cattle highlight a differential modulation of metabolism and immune response during infection by Trypan... by Peylhard, Moana, Berthier, David, Dayo, Guiguigbaza-Kossigan, Chantal, Isabelle, Sylla, Souleymane, Nidelet, Sabine, Dubois, Emeric, Martin, Guillaume, Sempéré, Guilhem, Flori, Laurence, Thévenon, Sophie

“…Exposed cattle include trypanosusceptible indicine breeds, severely affected by the disease, and West African taurine breeds called trypanotolerant owing to their ability to control parasite development, survive and grow in enzootic areas. Until now the genetic basis of trypanotolerance remains unclear. …”
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Hybrid intelligence framework for optimizing shear capacity of lightweight FRP-reinforced concrete beams by Iman Faridmehr, Moncef L. Nehdi, Mohammad Ali Sahraei, Kiyanets Aleksandr Valerievich, Chiara Bedon

“…Multi-objective optimization was deployed to integrate Genetic Algorithms (GA) and fmincon to optimize beam parameters for maximizing the shear capacity, Vc. …”
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