Gallbladder Carcinomas: An Immunoprognostic Evaluation of P53; Bcl-2; CEA and Alpha-Fetoprotein by R Kanthan, JM Radhi, SC Kanthan

“…The p53 gene is the most frequently mutated gene in many human cancers, including those of the colon, breast, lung, esophagus, liver and brain. Such genetically mutated tumours are generally associated with progression of the disease and poor clinical outcome. …”
Get full text

Heteromericarpy of Heracleum sosnowskyi Manden. (Umbelliferae = Apiaceae) by K. G. Tkachenko

Get full text

Mitochondrial Complex I Deficiency among Egyptian Pediatric Patients with Steroid-Resistant Nephrotic Syndrome by Doaa M. Abdou, AbdelAal Mohamed, Mohamed Abdulhay, Sara El Khateeb

“…The objective of the current study is to measure the activity of mitochondrial complex I in renal biopsies obtained from pediatric patients diagnosed with SRNS compared to steroid-sensitive nephrotic syndrome (SSNS) patients in order to elucidate its role in pathogenesis and the prognosis for further genetic work. Subjects and Method. Renal biopsies of 120 patients diagnosed with nephrotic syndrome based on clinical and laboratory findings, divided into two groups, SRNS (60 patients) and SSNS (60 patients). …”
Get full text

Effect of autologous platelet-rich plasma treatment on patients with thin endometrium by Tung Nguyen Thanh, Ai Hoang Van, Son Trinh The, Lan Do Ngoc, Hang Doan Thi, Trang Quan Van, Khoa Ba Tran, Sang Trieu Tien

Get full text

Sea buckthorn cultivars promising for mechanized harvesting by cutting fruit-bearing branches by Yu. A. Zubarev, A. V. Gunin, E. I. Panteleeva, A. V. Vorobyeva

Get full text

Establishment of a Comprehensive Platform for Sustained Delivery of Yoga Therapy for Sickle Cell Anemia in Rural and Remote Tribal Pocket in India by Thota Neeraja, Ramesh Nanjundaiah Mavathur, Himanshu Anirudhbhai Shukla, Manmath Gharote

“…Background: Sickle cell anemia (SCA) is the most common inherited genetic red blood cell disorder, highly prevalent in the tribal population residing in the Central India. …”
Get full text

Pivotal roles of melanopsin containing retinal ganglion cells in pupillary light reflex in photopic conditions by Jeremy Matthew Bohl, Abdul Rhman Hassan, Zachary J. Sharpe, Megi Kola, Angela Shehu, Deborah Langrill Beaudoin, Tomomi Ichinose

“…Previous studies have investigated the roles of photoreceptors and ipRGCs in PLR using genetically-modified mouse models. Herein, we acutely ablated photoreceptors using N-nitroso-N-methylurea (MNU) to examine the roles of ipRGCs in the PLR. …”
Get full text

Definition of a Novel Cuproptosis-Relevant lncRNA Signature for Uncovering Distinct Survival, Genomic Alterations, and Treatment Implications in Lung Adenocarcinoma by Zhuning Wang, Junqiao Yao, Tengyu Dong, Xing Niu

“…We collected transcriptome expression profiling, clinical information, somatic mutation, and copy number variations from TCGA-LUAD cohort retrospectively. The genetic alterations of cuproptosis genes were systematically assessed across LUAD, and cuproptosis-relevant lncRNAs were screened for defining a LASSO prognostic model. …”
Get full text

Activity of gemmogenesis in regenerated plants of hazelnut cv. ‘Akademyk Yablokov’ and antibiotic therapy for elimination of bacterial contamination <i>in vitro</i> by T. A. Krasinskaya

Get full text

Volt/VAr Regulation of the West Mediterranean Regional Electrical Grids Using SVC/STATCOM Devices With Neural Network Algorithms by H. Feza Carlak, Ergin Kayar

“…The modeled power system is optimized for the size and location of the FACTS devices by applying genetic algorithms (GAs) and particle swarm optimization (PSO) algorithms to the selected busbars of the FACTS devices, a strategy designed to significantly reduce system losses. …”
Get full text

Exploring potential therapeutic targets for small cell lung cancer based on transcriptomics combined with Mendelian randomization analysis by Zhicheng Liao, Pengcheng Jia, Yifan Li, Zhihui Zheng, Jizhou Zhang

“…ObjectiveThe main objective of this study was to explore and identify new genetic targets in small-cell lung cancer (SCLC) through transcriptomics analysis and Mendelian randomization (MR) analysis, which will help in the subsequent development of new therapeutic interventions.MethodsIn this study, we extracted the SCLC dataset from the Gene Expression Omnibus (GEO) database, processed the data, and screened out differentially expressed genes (DEGs) using R software. …”
Get full text

A review of artificial intelligence techniques for optimizing friction stir welding processes and predicting mechanical properties by Roosvel Soto-Diaz, Mauricio Vásquez-Carbonell, Jose Escorcia-Gutierrez

“…Hybrid models combining AI with optimization algorithms, such as particle swarm optimization (PSO) and genetic algorithms, were particularly effective. These models demonstrated high precision in predicting tensile strength and detecting internal defects, significantly improving joint quality. …”
Get full text

The molecular prevalence of Theileria equi in the Arabian stallion in Egypt with special reference to biochemical parameters by Noora F. Thabet, Omaima M. Kandil, Omnia M. Kandil, Khalid M. Fararh

Get full text

Age-Related Trends in Body Composition among Women Aged 20–80 Years: A Cross-Sectional Study by Nirmala Rathnayake, Hasanga Rathnayake, Sarath Lekamwasam

“…The determinants of body composition are likely to vary geographically due to the diversity of genetic and environmental factors between populations. …”
Get full text

A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis. by Courtney A Granville, Regan M Memmott, Andria Balogh, Jacopo Mariotti, Shigeru Kawabata, Wei Han, Jaclyn Lopiccolo, Jason Foley, David J Liewehr, Seth M Steinberg, Daniel H Fowler, M Christine Hollander, Phillip A Dennis

“…Foxp3+ cells were depleted using rapamycin, an antibody, or genetic ablation.<h4>Results</h4>Exposure of A/J mice to a tobacco carcinogen tripled lung-associated Foxp3+ cells prior to tumor development. …”
Get full text

Predictive factors for the diagnosis of coeliac disease in children and young people in primary care: A systematic review and meta-analysis. by Christian E Farrier, Marta Wanat, Anthony Harnden, Amy Paterson, Nia Roberts, Defne Saatci, Jennifer Hirst

“…Included studies were observational or randomized trials reporting the risk of CD when exposed to predictive factor(s) in people ≤25 years of age. Genetic factors were excluded. Risk of Bias was assessed using the Newcastle-Ottawa Scale. …”
Get full text

Hepatoprotective Effects of Crude Stem Bark Extracts and Solvent Fractions of Cordia africana against Acetaminophen-Induced Liver Injury in Rats by Gudeta Duga Geresu, Shemsu Umer, Mahlet Arayaselassie, Genet Ashebir, Eyasu Makonnen

Get full text

Targeted next-generation sequencing for antimicrobial resistance detection in ventilator-associated pneumonia by Yuting Li, Yanfang Jiang, Hao Liu, Yao Fu, Junying Lu, Hongyan Li, Lulu Sheng, Dejian Gu, Dong Zhang

Get full text

Biodiversity Change in Cultural Landscapes—The Rural Hotspot Hypothesis by Carsten Neumann, Robert Behling, Gabriele Weiss

“…Spatiotemporal dimensions of backyard pressures involving material fluxes, species exchange and retention, alternation of site conditions, and local genetic adaptation are delineated for different backyard features, including building structures, gardens, lawns, and paved grounds. …”
Get full text

Metagenomic insights and biosynthetic potential of Candidatus Entotheonella symbiont associated with Halichondria marine sponges by Hiyoung Kim, Jiyeong Ahn, Jaebum Kim, Hahk-Soo Kang

“…Entotheonella pangenome, with almost no overlapping BGCs between different MAGs. The cryptic and genetically unique BGCs present in the Ca. Entotheonella pangenome represents a promising source of new bioactive natural products.…”
Get full text