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13001
Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro
Published 2025-03-01“…However, the species faces challenges in genetic breeding and germ-line preservation due to its late sexual maturity (2–3 years for males and 3–4 years for females) and single spawning cycle. …”
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13002
Association between Brain-Derived Neurotrophic Factor (BDNF) Levels in 2nd Trimester Amniotic Fluid and Fetal Development
Published 2018-01-01“…The development of the fetal nervous system mirrors general fetal development, comprising a combination of genetic resources and effects of the intrauterine environment. …”
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13003
Therapy of genomic unstable solid tumours (WHO grade 3/4)in clinical stage III/IV using individualised neoantigen tumour peptides-INP trial (individualised neoantigen tumour peptid...
Published 2022-06-01“…Currently, a few studies have reported using a mixture of neoantigen peptides derived from multiple genetic mutation sites in the treatment of genomic unstable advanced solid malignancies. …”
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13004
Actinomycete-Derived Pigments: A Path Toward Sustainable Industrial Colorants
Published 2025-01-01“…Scale-up of production and yield optimization challenges have been circumvented with the aid of biotechnology advancements, including genetic engineering and innovative fermentation and extraction methods, which have enhanced these bio-pigments’ viability and cost-competitiveness. …”
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13005
Targeting EP2 Receptor Improves Muscle and Bone Health in Dystrophin<sup>−/−</sup>/Utrophin<sup>−/−</sup> Double-Knockout Mice
Published 2025-01-01“…Duchenne muscular dystrophy (DMD) is a severe genetic muscle disease occurring due to mutations of the dystrophin gene. …”
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13006
Algorithm of management of patient with alcohol-induced liver disease
Published 2011-02-01“…The main of them include amount of taken alcohol, gender, genetic polymorphism of enzymes involved in alcohol metabolism (метаболизме алкоголя?)…”
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13007
Promising Therapeutic Functions of Bone Marrow Mesenchymal Stem Cells Derived-Exosome in Asthma
Published 2022-01-01“…Extracellular vesicles (EVs) enriched in body fluid were characterized as subcomponents of extracellular vesicles and delivered carriers combined with genetic messages in vivo. The therapeutic potential of exosomes has become a research hotspot in many diseases. …”
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13008
Butyric Acid Modulates Gut Microbiota to Alleviate Inflammation and Secondary Bone Loss in Ankylosing Spondylitis
Published 2024-12-01“…While the exact pathogenetic mechanism of AS remains unclear, previous reports have highlighted the involvement of genetic factors, immune responses, and gut microbiota dysregulation in the development of this condition. …”
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13009
Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy
Published 2025-01-01“…Methods: We generated a mouse model of SCM induced by lipopolysaccharide (LPS) and then obtained comprehensive metabolic and genetic data from SCM mouse hearts using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) and RNA sequencing (RNA-seq). …”
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13010
Predictors for Gingival Index in Middle-Aged Asian Indians with Type 2 Diabetes from South India: A Cross-Sectional Observational Study
Published 2018-01-01“…Asian Indians develop type 2 diabetes mellitus (T2DM) much earlier as compared to White Caucasians, due to unique phenotypic and genetic architecture. Periodontitis in T2DM patients is often a neglected clinical feature. …”
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13011
Missing Risk Factor Prediction in Cardiovascular Disease Using a Blended Dataset and Optimizing Classification With a Stacking Algorithm
Published 2025-01-01“…ABSTRACT Machine learning is important in the treatment of heart disease because it is capable of analyzing large amounts of patient data, such as medical records, imaging tests, and genetic information, in order to identify patterns and predict the risk of developing heart disease. …”
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13012
Atypical presentation of Andersen-Tawil syndrome: heart failure with reduced ejection without periodic paralysis or dysmorphic features
Published 2024-12-01“…Ultimately, he was diagnosed with non-ischaemic dilated cardiomyopathy and referred for genetic testing, which revealed a KCNJ2 variant. Shortly after discharge, he experienced a 55-second run of ventricular tachycardia, necessitating the placement of a single-chamber ICD. …”
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13013
The rationale, design of the Assisted reproductive technology cohort nested in a pre-pregnancy family cohort (APP-Cohort)
Published 2025-12-01“…With a focus on various types of risk factors such as genetic, environmental, and shared familial traits, the ongoing follow-up of this study will enable researchers to evaluate and distinguish the impacts of these factors on pregnancy outcomes, perinatal health, and children’s health for individuals conceived naturally versus those conceived through ART. …”
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13014
Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells
Published 2025-01-01“…Enrichment of pathways related to neurogenesis, axon guidance, and synaptic signaling varied across donors, highlighting the impact of genetic and epigenetic individuality on NSPC behavior.…”
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13015
Normalization of Cystic Fibrosis Immune System Reverses Intestinal Neutrophilic Inflammation and Significantly Improves the Survival of Cystic Fibrosis MiceSummary
Published 2025-01-01“…Background & Aims: Cystic fibrosis (CF) is an autosomal recessive genetic disorder, affecting multiple organ systems. …”
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13016
Molecular characterization and lineage analysis of canine astrovirus strains from dogs with gastrointestinal disease in Ecuador based on ORF-2 gene analysis
Published 2025-02-01“…Given the high frequency of CaAstV infections in dogs with gastroenteritis and its high genetic variability, it emphasizes the need to implement routine diagnostic measures that include this pathogen as one of the main causes of the disease and a risk agent in case of multiple infections.…”
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13017
Current state of INRA research on olive trees in Morocco
Published 2024-09-01“…This olive research program is carried out at INRA Marrakech and INRA Meknes and includes five main topics: (i) Conservation and valorization of genetic resources; (ii) Irrigation and fertilization management; (iii) Integrated pest management; (iv) Olive oil quality and valorization; and (v) Olive value chain analysis. …”
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13018
Haploidentical hematopoietic stem cell transplantation using post-transplant cyclophosphamide in patients with inborn errors of immunity: Experience in a reference center in Colomb...
Published 2024-12-01“…Inborn errors of immunity is a diverse group of rare diseases caused by over 400 genetic mutations affecting the immune system and increasing infection susceptibility, autoimmunity, and malignancy. …”
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13019
First whole genome report of Mangrovibacter phragmitis PSU-3885–11 isolated from a patient in Thailand
Published 2025-01-01“…Moreover, comparative genomic analysis showed 99.32 % average nucleotide identity (ANI) similar to M. phragmitis MP23, and several antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) were identified in the PSU-3885–11 genome which may contribute to its ability to survive in diverse environments, including human hosts. …”
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13020
Endometriosis does not impact aneuploidy rates of products of conception in IVF population
Published 2025-01-01“…Abstract It has been debated whether endometriosis (EMS) adversely affects oocyte quality, potentially leading to a higher incidence of genetically unbalanced embryos or other egg factors that affect the developmental potential. …”
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