Characterization of a chemically induced osteoarthritis model in zebrafish by Gongyi Xiao, Jin Qin, Huiping Yang, Qizhi Song, Ruobin Zhang, Junlan Huang, Yuexi Mou, Wen Liu, Xianding Sun, Mao Nie

“…Moreover, zebrafish present distinct advantages, including robust regenerative abilities, genetic editing simplicity, and efficient drug screening. …”
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Diversity of Rhizophydiales (Chytridiomycota) in Thailand: unveiling the hidden gems of the Kingdom by Vedprakash G. Hurdeal, Joyce E. Longcore, E. B. Gareth Jones, Kevin D. Hyde, Eleni Gentekaki

“…By meticulously exploring their morphological characteristics and genetic makeup, we expand the known catalogue of fungal diversity by describing Alphamyces thailandicus, Angulomyces ubonensis, Gorgonomyces aquaticus, G. chiangraiensis, G. limnicus, Pateramyces pingflumenensis, Terramyces aquatica, and T. flumenensis and also provide valuable insights into the intricacies of this order. …”
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Każde dziecko i każda jego cecha ma swoiste tempo rozwoju, modyfikowane przez warunki życia w danym okresie. (Raport 2 z dwuletnich comiesięcznych badań na Jukatanie w Meksyku)... by Napoleon Wolański, Armando Rojas, Graciela Valentin, Anna Siniarska

“…These phenomena depend rather on condition s in which the development of each individual occurs, as well as on its genetic predispositions and eco-sensitivity. It is probable, that differences in onset and intensity of pubertal spurt depend on alternations between periods of saltations and stasis of growth processes and on changes in body mass. …”
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Data Mining Evidences Variabilities in Glucose and Lipid Metabolism among Fish Strains: A Case Study on Three Genotypes of Gibel Carp Fed by Different Carbohydrate Sources by Xuerong Song, Haokun Liu, Junyan Jin, Dong Han, Xiaoming Zhu, Yunxia Yang, Shouqi Xie

“…Furthermore, there were numerous interactions between carbohydrate sources and strains for growth, metabolites, and transcriptional control, confirming the existence of genetic polymorphisms in carbohydrate use in gibel carp. …”
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Incidence of extended spectrum beta-lactamase (ESBL) producing Escherichia coli isolated from women with urinary tract infections in Jordan by Rania Al-Groom

“…The blaCTX-M gene was genetically confirmed in 20 (10.1%) of the isolates. …”
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Metabarcoding the night sky: Monitoring landscape-scale insect diversity through bat diet by Cynthia Tobisch, Svenja Dege, Bernd Panassiti, Julian Treffler, Christoph Moning

“…Our study shows that genetic analysis of bat feces provides an efficient and promising approach to assess insect diversity patterns at the landscape level, and highlights the potential of widespread bat species for the monitoring of terrestrial insects at large scales.…”
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Major individual and regional variations in unit entrainment by oscillations of different frequencies by Mohamed Badawy, Ian T. Kim, Alon Amir, Mohammad M. Herzallah, Luisa F. Gomez-Alatorre, Drew B. Headley, Denis Paré

“…Perhaps those are less susceptible to genetic variations. While our findings do not allow us to determine which explanation is correct, they do highlight the perils of averaging.…”
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Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling by Raquel Arantes Megid, Guilherme Gomes Ribeiro, Izabela Natalia Faria Gomes, Ana Carolina Laus, Letícia Ferro Leal, Letícia Ferro Leal, Luciane Sussuchi da Silva, Abu-Bakr Adetayo Ariwoola, Josiane Mourão Dias, Rui Manuel Reis, Rui Manuel Reis, Renato Jose da Silva-Oliveira, Renato Jose da Silva-Oliveira

“…BackgroundThe molecular non-genetic changes of resistance to sotorasib are currently uncertain. …”
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Scalable Fabrication of Light-Responsive Superhydrophobic Composite Phase Change Materials via Bionic-Engineered Wood for Solar–Thermal Energy Management by Yang Meng, Jiangyu Zhang, Yuchan Li, Hui Jiang, Delong Xie

“…Herein, a multifunctional composite phase change material (CPCM) is developed using a balsa-derived morphology genetic scaffold, engineered via bionic catechol surface chemistry. …”
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SLC6A4 5HTTLPR Polymorphism Affects Insulin Secretion in Patients with Polycystic Ovary Syndrome by Barbara Šenk, Katja Goričar, Nika Aleksandra Kravos, Mojca Jensterle Sever, Andrej Janež, Vita Dolžan

“…To investigate in a pilot study of genetic polymorphisms in serotonin system influencing basal- and glucose-stimulated insulin secretion in women with polycystic ovary syndrome (PCOS). …”
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Self-beneficial transactional social dynamics for cooperation in Shwachman-Diamond syndrome: a mixed-subject analysis using computational pragmatics by Arthur Trognon, Arthur Trognon, Arthur Trognon, Natacha Stortini, Natacha Stortini, Coralie Duman, Coralie Duman, Nami Koïdé, Ewa Skupinska, Ewa Skupinska, Hamza Altakroury, Alizée Poli, Alizée Poli, Loann Mahdar-Recorbet, Loann Mahdar-Recorbet, Blandine Beaupain, Jean Donadieu, Michel Musiol, Michel Musiol, Michel Musiol

“…BackgroundShwachman-Diamond Syndrome (SDS) is a rare genetic disorder with documented cognitive and behavioral challenges. …”
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Randomised cross-over trial of vildagliptin and pioglitazone as add-on therapy in patients with type 2 diabetes: predicting Which One is Right Here (WORTH) study protocol by Yannan Jiang, Tony R Merriman, Rui Qian Yeu, Rebecca Brandon, Dale Griffiths, Kate Smallman, Allan Moffitt, Glenn Doherty, Ryan Paul, Jennie Harré Hindmarsh, Kerry Macaskill-Smith, Brandon Orr-Walker, Rinki Murphy

“…The objective of this study was to test whether glycaemic response to representative treatments of dipeptidyl peptidase-4 inhibitors (vildagliptin) and thiazolidinediones (pioglitazone) varies according to ethnicity, gender, baseline obesity, triglyceride level or genetic variation.Methods This is a multicentre, two-period, two-treatment, open-label, randomised cross-over trial of vildagliptin and pioglitazone as second-line or third-line therapy in patients with T2D who have suboptimal glycaemic control on metformin and/or sulfonylurea therapy. …”
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The Protective Role of HLA-DRB113 in Autoimmune Diseases by Andreia Bettencourt, Cláudia Carvalho, Bárbara Leal, Sandra Brás, Dina Lopes, Ana Martins da Silva, Ernestina Santos, Tiago Torres, Isabel Almeida, Fátima Farinha, Paulo Barbosa, António Marinho, Manuela Selores, João Correia, Carlos Vasconcelos, Paulo P. Costa, Berta Martins da Silva

“…Autoimmune diseases (AIDs) are characterized by a multifactorial aetiology and a complex genetic background, with the MHC region playing a major role. …”
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Clinical phenotypes and associated factors in knee osteoarthritis in an African black population by Charles Sougué, Malick Diallo, Yannick Laurent Tchenadoyo Bayala, Ismaël Ayouba Tinni, Fulgence Kaboré, Wendlassida Joelle Stéphanie Zabsonré Tiendrebeogo, Patrick Wendpouiré Hamed Dakouré, Dieu-Donné Ouedraogo

“…The study identified five clinical phenotypes through clustering: 152 patients (47.3 ​%) exhibited the “osteoporotic” phenotype, 113 patients (35.2 ​%) exhibited the “metabolic” phenotype, 17 patients (5.3 ​%) exhibited the “genetic” phenotype, 24 patients (7.4 ​%) exhibited the “biomechanical” phenotype, and 15 patients (4.6 ​%) exhibited the “post-traumatic” phenotype. …”
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Arrested Puberty in an Adolescent Male with Anorexia Nervosa Successfully Resumed with Multidisciplinary Care by Diana Simão Raimundo, Carolina Figueiredo, Ana Raposo, Bernardo Dias Pereira

“…The normal development of puberty depends on the specific pulsatility of gonadorelin, which is finely regulated by genetic and environmental factors. In the published literature, eating disorders figure as a cause of pubertal delay/arrest in females but are rarely considered in males with disordered puberty. …”
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Integrated Planning for Shared Electric Vehicle System Considering Carbon Emission Reduction by Xiaohui Sun, Yumei Mi, Askar Ahtam, Zhi Zuo

“…By applying these models to the Chicago Sketch network and using a genetic algorithm to solve the models, it is concluded that the optimal outlet location solution considering carbon emission reduction will increase the outlet construction cost and user travel time cost. …”
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Copper and iron as unique trace elements linked to fibromyalgia risk by Wenxing Zeng, Minhua Hu, Luyao Ma, Feng Huang, Ziwei Jiang

“…This study employed Mendelian randomization (MR) to assess potential causal relationships between 15 major trace elements and the risk of FM, focusing on the specific roles of elements that show significant associations. Genetic instrumental variables (single nucleotide polymorphisms, SNPs), related to these trace elements and FM were extracted from genome-wide association studies (GWAS). …”
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Evolutionary analysis of genes associated with the sense of balance in semi-aquatic mammals by Yuehuan Dong, Qinguo Wei, Guolei Sun, Xiaodong Gao, Tianshu Lyu, Lidong Wang, Shengyang Zhou, Xibao Wang, Yongquan Shang, Lupeng Shi, Honghai Zhang

“…Our study endeavors to unravel the genetic components associated with the sense of balance in semi-aquatic mammals and to examine the evolutionary trajectories of these genes, shed light on the molecular mechanisms underlying the adaptive evolution of balance perception in semi-aquatic mammals. …”
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Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice by Wei Song, Zi-ming Zhou, Le-le Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yong-mei Zhang

“…TREM-1 inhibition, both genetically and pharmacologically, reduced monocyte infiltration, alleviated neuroinflammation, and preserved dopaminergic neurons, resulting in improved motor function. …”
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Characteristic external genitalia in male neonates with 5α-reductase deficiency by Takeshi Munenaga, Yosuke Ichihashi, Satsuki Nakano, Hironori Shibata, Takeshi Sato, Hiroshi Asanuma, Keiko Homma, Tomonobu Hasegawa, Tomohiro Ishii

“…This study enrolled 31 Japanese cases of 46,XY DSD whose external genitalia was examined during the neonatal period; four were diagnosed as 5αRD and 15 were defined as non-5αRD by genetic analysis of SRD5A2 or urinary steroid metabolites. …”
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