Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development. by Theresa A Reimels, Mia Steinberg, Hua Yan, Sivan Shahar, Ashley Rosenberg, Kristina Kalafsky, Max Luf, Lindsay Kelly, Stacia Octaviani, Cathie M Pfleger

“…Subsequently, we reported that Rabex-5 inhibits Notch signaling in the Drosophila hematopoietic system. Here we report genetic interactions using Rabex-5 transgenes encoding domain-specific mutations that show that Rabex-5 requires an intact E3 domain to inhibit Notch signaling in the epithelial tissue of the developing wing. …”
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Tension Recordings from Primary Bronchi in Acta2-GCaMP8.1-mVermilion Transgenic Mice by Qais Khalaf, Srijit Ghosh, Keith Thornbury

“…Transgenic Acta2-GCaMP8.1-mVermilion (GCaMP) mice express a genetically encoded intracellular fluorescent Ca2+ indicator in smooth muscle cells, have been developed to facilitate the study of Ca2+. …”
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On the Search for Supersingular Elliptic Curves and Their Applications by Ismel Martinez-Diaz, Rashad Ali, Muhammad Kamran Jamil

“…As our main result, we define for the first time an objective function to measure the supersingularity in ordinary curves, and we apply local search and a genetic algorithm using that function. The study not only finds these supersingular elliptic curves but also investigates possible uses for them. …”
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Adaptive characteristics of promising soybean cultivars under the conditions of the south of the Russian Far East by E. S. Butovets, L. M. Lukyanchuk

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Parametric Evaluation of Simultaneous Effects of Damaged Zone Parameters and Rock Strength Properties on GRC by Ali Ghorbani, Hadi Hasanzadehshooiili, Amin Eslami

“…Besides, effects of intermediate principal stress and the exponential decaying dilation parameter are taken into account thanks to adoption of the unified strength criterion (USC) as the material strength criteria. To do so, genetic algorithm (GA) via the method of evolutionary polynomial regression (EPR) is used to find a relationship between a number of 19 affecting parameters on the GRC as the input, and the internal support pressure as the target of prediction. …”
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The Role of Imperial Authorities in Electing Muslim Clerics across Yenisei Governorate, Mid-Nineteenth to Early Twentieth Centuries by Elena A. Shershneva

“…To accomplish this, the chronological and historic-genetic methods are used. Results. The region’s sociohistorical agenda made any elections of required clerics somewhat problematic. …”
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Narrative Literature Review of Potential Atrial Fibrillation Mechanism of Action Induced by Discontinuation of Benzodiazepines by Agnė Okulevičiūtė, Gabija Laubner Sakalauskienė

“…There is evidence that genetic diversity can influence the response to BZDs through GABA receptors. …”
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VOICES-POSITIONS IN DISCOURSES: HOW IS IDENTITY POSSIBLE? by T. V. Podolska

“…Interdisciplinary research perspective allowed using a comprehensive methodology where, complementing each other, there are phenomenological, cultural, anthropological, hermeneutic, systematic, historical and genetic methods and method historical-philosophical and socio-cultural comparative studies. …”
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Performance Evaluation of Different Blood Levels of Crossbred Dorper Sheep and Farmers’ Perception Toward Crossbred Dorper Sheep in Central South Zone, Southern Ethiopia by Kebede Habtegiorgis, Deribe Gemiyo, Ayele Abebe, Addisu Jimma

“…The breed could be promoted as an optional genetic material. To ensure better survival of crossbred lambs, it is important to integrate improved management systems, such as enhanced feed, housing, and healthcare.…”
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Seminal Fluid-Mediated Inflammation in Physiology and Pathology of the Female Reproductive Tract by Anthonio O. Adefuye, Henry A. Adeola, Kurt J. Sales, Arieh A. Katz

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Assessment of cold resistance in <i>Momordica charantia</i> L. accessions according to pollen germination at low temperatures <i>in vitro</i> by Yu. V. Fotev

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Recent methods for the diagnosis and differentiation of ameloblastoma: a narrative review by Ke Hu, Xudong Zhang, Ruixue Chen, Xiangjun Li

“…Laboratory tests are more suitable for detecting genetic alterations and identifying certain markers. …”
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Intraspecific Morphological Variations among the Populations of Milicia excelsa, Pouteria adolfi-friedericii, and Prunus africana in Different Natural Forests of Southwest Ethiopia by Mohammed Adefa Seid, Yigardu Mulatu Mengesha

“…Therefore, it is important to look for conservation strategies, such as domestication, to maintain and improve the variability and genetic quality among the populations in a wider scale of the ecological and social environment.…”
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Comparative ecological testing of <i>Achillea millefolium</i> (L.) cultivars in Moscow Province by I. N. Korotkikh, N. V. Nevkrytaya, T. V. Platonova

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Familial Aggregation for Ischemic Heart Disease by José Leandro Pérez Guerrero, William Arias Salazar

“…<strong>Background:</strong> ischemic heart disease is a nosological entity of multifactorial origin with genetic predisposition and susceptible to environmental changes. …”
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Health Canada's use of its priority review process for new drugs: a cohort study by Joel Lexchin

“…The purpose of this study is to compare Health Canada's use of priority reviews to therapeutic ratings from two independent organisations, the Patented Medicine Prices Review Board (PMPRB) and the French drug bulletin Prescrire International, over the period 1 January 1997–31 December 2012.Design Cohort study.Data sources Annual reports of the Therapeutic Products Directorate, and the Biologics and Genetic Therapies Directorate; evaluations of therapeutic innovation from PMPRB and Prescrire International; WHO Collaborating Centre for Drug Statistics Methodology.Interventions Assessments by PMPRB and Prescrire International treated as a gold standard for postmarket therapeutic value.Primary and secondary outcome measures Drug-by-drug comparison between the review status from Health Canada and the therapeutic status from PMPRB/Prescrire using κ values, and positive and negative predictive values. …”
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Coagulase gene and agr complex polymorphism-based genotyping of <i>Staphylococcus aureus</i> isolated from non-human primates by V. A. Kalashnikova

“…The paper demonstrates results of molecular and genetic examination of Staphy-lococcus aureus isolated from non-human primates. …”
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Phylogenetic Aspects of Antibiotic Resistance and Biofilm Formation of P. aeruginosa Isolated from Clinical Samples by Maryam Motevasel, Masoud Haghkhah, Negar Azimzadeh

“…It is distinguished there were similar genetic patterns between detected isolates from urine and could be concluded that the urinary tract played a critical role in maintaining and transferring biofilm drug-resistant genes of P. aeruginosa in clinical sites. …”
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Studying steppe cherry cultivars in Chelyabinsk Province by A. A. Vasiliev, F. M. Gasymov, V. R. Galimov

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Finite strain formulation of the discrete equilibrium gap principle: application to direct parameter estimation from large full-fields measurements by Peyraut, Alice, Genet, Martin

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