A scoping review of published literature on chikungunya virus. by Mariola Mascarenhas, Sophiya Garasia, Philippe Berthiaume, Tricia Corrin, Judy Greig, Victoria Ng, Ian Young, Lisa Waddell

“…In addition, a repository of CHIKV mutations associated with evolutionary fitness and adaptation has been created by compiling and characterizing these genetic variants as reported in scientific literature.…”
Get full text

Breeding for postharvest physiological deterioration in cassava: problems and strategies by Wilton Mbinda, Asunta Mukami

“…In this review, we discuss the available knowledge on (i) physiology and biochemistry of cassava storage root with regard to PPD (ii) strategies for minimizing PPD in cassava storage roots (iii) traits associated with PPD tolerance as essential targets for prolonging cassava storage root shelf life, and (iv) suggestions for novel genomic tools and modern genetic and breeding approaches for prolonging shelf-life in cassava storage roots. …”
Get full text

Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food. by Laura Dearden, Isadora C Furigo, Lucas C Pantaleão, L W P Wong, Denise S Fernandez-Twinn, Juliana de Almeida-Faria, Katherine A Kentistou, Maria V Carreira, Guillaume Bidault, Antonio Vidal-Puig, Ken K Ong, John R B Perry, Jose Donato, Susan E Ozanne

“…We demonstrate that targets of miR-505-5p are enriched in fatty acid metabolism pathways and overexpression of miR-505-5p decreased neuronal fatty acid metabolism in vitro. miR-505-5p targets are associated with increased BMI in human genetic studies. Intra-cerebroventricular injection of miR-505-5p in wild-type mice increased HFD intake, mimicking the phenotype observed in offspring exposed to maternal obesity. …”
Get full text

Image Evolution Using 2D Power Spectra by Michael Gircys, Brian J. Ross

“…We refine fitness measures based on Fourier analysis and spatial frequency and apply them within a genetic programming environment for image synthesis. …”
Get full text

A core set of risk factors in individuals at risk of rheumatoid arthritis: a systematic literature review informing the EULAR points to consider for conducting clinical trials and... by Daniel Aletaha, Kulveer Mankia, Paul Emery, Deshire Alpizar-Rodriguez, Andreas Kerschbaumer, Andrea Di Matteo, Heidi Siddle, Joel Kerry

“…Fifty-three articles included data on risk factors including autoantibodies, subclinical inflammation on imaging, clinical features, serum and cellular biomarkers and genetic markers. Risk factors were dependent on the at-risk population. …”
Get full text

Understanding the Spectrum of Mild Clinical Outcomes and Novel Findings in Arterial Tortuosity Syndrome Among Qatari Patients: Implications of SLC2A10 Mutation by Muhammed Riyas K. Rahmath, Haytham Ibrahim, Muhammad Faiyaz-Ul-Haque, Zafar Nawaz, Ahmad Zitoun, Ahmed Hussein, Ahmed Sadek, Ayman El-Menyar, Reema Kamal, Hassan Al-Thani, Gulab Sher

“…The cohort study included 21 patients who were genetically confirmed by mutations in the SLC2A10 gene. …”
Get full text

Clinical Phenotype of Fucosidosis in Cuba by Víctor Jesús Tamayo Chang, George Alberto Pérez Benítez

“…<br /><strong>Method:</strong> a case series study was carried out, for which the clinical and genetic histories of patients with α-L-fucosidase enzyme activity in leukocytes were analyzed, quantified by spectrofluorimetry 30 % lower than the activity of healthy controls. …”
Get full text

Mammalian mitochondrial inorganic polyphosphate (polyP) and cell signaling: Crosstalk between polyP and the activity of AMPK by Renata T. Da Costa, Anna Nichenko, Matheus M. Perez, Malgorzata Tokarska-Schlattner, Sheida Kavehmoghaddam, Vedangi Hambardikar, Ernest R. Scoma, Erin L. Seifert, Uwe Schlattner, Joshua C. Drake, Maria E. Solesio

“…Moreover, increased levels of polyP activate AMPK. Accordingly, the genetic downregulation of AMPKF0611 impairs polyP levels in both SH-SY5Y cells and in the brains of female mice. …”
Get full text

Comparative characterization of Leporipoxvirus members’ reproduction in continuous cell culture by O. G. Lapteva, S. G. Yurkov, I. P. Sindryakova, A. V. Lunitsin

“…Prepared cultures were identified as myxoma virus and Shope fibroma virus with molecular genetic analysis. Tests of the viruses for their antigenic relatedness showed that antibodies against myxoma virus were able to neutralize Shope fibroma virus also. …”
Get full text

Characterization and molecular biological identification of tick species in Nanjing city by Luyao SUN, Xuemin CHEN, Bingdong SONG, Yan ZHANG, Yanqun SUN, Yue MIN, Shougang ZHANG

“…Tick species composition varied among habitats and animal hosts. No significant genetic variation within tick species was observed.…”
Get full text

The Role of the Enterohepatic Circulation of Bile Salts and Nuclear Hormone Receptors in the Regulation of Cholesterol Homeostasis: Bile Salts as Ligands for Nuclear Hormone Recept... by Richard N Redinger

“…The coordinated effect of lipid activated nuclear hormone receptors; liver X receptor (LXR), bound by oxysterol ligands and farnesoid X receptor (FXR), bound by bile acid ligands, act as genetic transcription factors to cause feed-forward cholesterol catabolism to bile acids and feedback repression of bile acid synthesis, respectively. …”
Get full text

Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization by Patrizia Cavadini, Alice Vismarra, Francesca Merzoni, Vittoria Di Giovanni, Maria Beatrice Boniotti, Lorenzo Capucci, Antonio Lavazza

“…This study aimed firstly to indirectly show through a seroepidemiological survey from 1998 to 2008 the circulation of RCVs strains in rabbit farms and then to genetically characterise RCV strains diagnosed in Italy in faecal and intestinal samples of wild and farmed rabbits collected in various regions in the following years (2000–2022). …”
Get full text

Enhancing Campus Mobility: Simulated Multi-Objective Optimization of Electric Vehicle Sharing Systems Within an Intelligent Transportation System Frameworks by Omar S. Aba Hussen, Shaiful J. Hashim, Nasri Sulaiman Member, S.A.R. Alhaddad, Bassam Y. Ribbfors, Masanobu Umeda, Keiichi Katamine

“…A simulation model was developed in MATLAB, utilizing the Non-dominated Sorting Genetic Algorithm (NSGA-II), a powerful multi-objective optimization technique that balances conflicting objectives to achieve the best trade-offs for operational efficiency. …”
Get full text

Arbuscular Mycorrhizal Fungi Associated with Myrciaria dubia in the Amazonia Region, Peru by Alexandra Jherina Pineda-Lázaro, Adela Vallejos-Tapullima, Angel David Hernández-Amasifuen, Santos Carballar-Hernández, Sixto Imán-Correa, Fernando Marcelo Carvajal-Vallejos, Orlando Ríos-Ramírez, Mike Anderson Corazon-Guivin

“…Likewise, the molecular analysis detected the presence of genetic material (rDNA) corresponding to AMF in the roots of both accessions. …”
Get full text

Studies on the Association of GCK and GCKR Polymorphisms with Susceptibility to Gestational Diabetes Mellitus: A Meta-Analysis by Hongxia Tu, Youyi Zhang, Mingyi Wang

“…Results: We included 20 studies, comprising 9745 GDM women and 15,830 controls. All genetic models showed a strong correlation between the GCK rs1799884 polymorphism and GDM, with carriers of the A allele exhibiting an increased risk. …”
Get full text

Occurrence and Multi-Locus Genotyping of <i>Giardia duodenalis</i> in Black Goats from Fujian Province, China by Shou-Xiao Huang, Kai Hu, Peng-Fei Fu, Si-Ang Li, Yang Liu, Zhipeng Niu, Dong-Hui Zhou

“…To evaluate the prevalence and genetic diversity of <i>G. duodenalis</i> in black goats, we collected 539 fecal samples from nine districts in Fujian Province, China. …”
Get full text

Muscle parameters in men and oxidative stress markers by Michał Pietruszewski, Judyta Nowak-Kornicka, Agnieszka Żelaźniewicz, Bogusław Pawłowski

“…Factors like lifestyle, diet, and genetic predisposition, which were not controlled in this study, could also influence the observed outcomes and should be included in future research.…”
Get full text

Current smoking improves ulcerative colitis patients’ disease behaviour in the northwest of China by Huihong Zhai, Wenyu Huang, Aiqin Liu, Qianqian Li, Qian Hao, Ling Ma, Feng Yang, Shutian Zhang

“…Several studies have revealed that both environmental and genetic factors play crucial roles in the formation and development of this disease. …”
Get full text

A Case-Control Association Study of RANTES (-28C>G) Polymorphism as a Risk Factor for Parkinson’s Disease in Isparta, Turkey by Nilufer Sahin-Calapoglu, Serpil Demirci, Mustafa Calapoglu, Baris Yasar

“…We have examined whether genetic polymorphisms at the genes encoding chemokines IL-8 (-251A>T), MCP-1 (-2518A/G), and RANTES (-28C>G) and chemokine receptors CCR2 (V64I) and CCR5 (-Δ32) were associated with sporadic PD risk in Isparta, Turkey. …”
Get full text

Challenges Faced by Nurses in Transitioning Pediatric Sickle Cell Disease Patients to Adult Care by Gifty Enyonam Amoaku, Delali Adwoa Wuaku, Vivian Efua Senoo-Dogbey

“…Background Sickle-cell disease is a common genetic red blood cell disorder with global concern. …”
Get full text