Indirect and direct interactions between grain aphid and parasitoid in the presence of symbiont Regiella insecticola by Yue Man, Delu Li, Minghui Wang, Zuqing Hu, Jean-Luc Gatti, Nicolas Desneux, Peng Han, Chen Luo

“…Methods We generated Sitobion avenae aphid clonal lines that are genetically identical but differ in Regiella insecticola infection. …”
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Influence of the A3669G Glucocorticoid Receptor Gene Polymorphism on the Metabolic Profile of Pediatric Patients with Congenital Adrenal Hyperplasia by Ricardo P. P. Moreira, Larissa G. Gomes, Guiomar Madureira, Berenice B. Mendonca, Tânia A. S. S. Bachega

“…Pediatric CAH patients have an increased risk of cardiovascular disease, and it remains unknown if genetic predisposition is a contributing factor. Glucocorticoid receptor gene (NR3C1) polymorphisms are associated with an adverse metabolic profile. …”
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Comparison of SNP Variation and Distribution in Indigenous Ethiopian and Korean Cattle (Hanwoo) Populations by Zewdu Edea, Hailu Dadi, Sang Wook Kim, Tadelle Dessie, Kwan-Suk Kim

“…The level of SNP variation identified in this particular study highlights that these markers can be potentially used for genetic studies in African cattle breeds.…”
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A microfluidics platform for simultaneous evaluation of sensitivity and side effects of anti-cancer drugs using a three-dimensional culture method by Yuki Kobayashi, Honoka Hashizume, Sotaro Takiguchi, Jiajue Ji, Ryuji Kawano, Keiichiro Koiwai, Haru Yamamoto, Mohamed Elbadawy, Tsutomu Omatsu, Amira Abugomaa, Masahiro Kaneda, Tatsuya Usui, Kazuaki Sasaki

“…The effects of drug perfusion on FMT and MI organoids were examined by measuring cell viability and performing genetic analysis. After 48 h of perfusion with toceranib (10 µM) or doxorubicin (1 µM), cell viability of FMT organoids was decreased compared to the non-perfusion condition. …”
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Comparative Study of <i>Phytolacca</i> Species Through Morphological, Chloroplast Genome, and Phylogenetic Analysis by Sumin Jeong, Yeseul Kim, Heewon Ji, Jun-Ho Song, Inkyu Park

“…This study has aimed to clarify the classification of <i>Phytolacca</i> species based on their morphology and genetic differences. The chloroplast genome of <i>P. acinosa</i> was sequenced and comparative analyses were conducted to identify the regions of variation and nucleotide diversity among the species. …”
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Molecular Characterization of Putative Virulence Determinants in Burkholderia pseudomallei by Suat Moi Puah, S. D. Puthucheary, Jin Town Wang, Yi Jiun Pan, Kek Heng Chua

“…These genes were extensively characterized at the molecular level, together with an additional gene BPSL3147 that had been identified by other investigators. Through a reverse genetic approach, single-gene knockout mutants were successfully constructed by using site-specific insertion mutagenesis and were confirmed by PCR. …”
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A new approach for evaluating maize transgressive segregants and their three-way cross potential in the S4 convergent breeding population by Nuniek Widiayani, Muhammad Fuad Anshori, Nasaruddin Nasaruddin, Muh Farid, Ifayanti Ridwan, Abd. Haris Bahrun, Muhammad Azrai, Amin Nur, Purnama Isti Khaerani, Willy Bayuardi Suwarno, Karlina Syahruddin, Naeem Khan, Majed A. Alotaibi, Mahmoud F. Seleiman

“…Based on the resulting study, the combination of ratio analysis, path analysis, best linear unbiased prediction, relative fitness, and selection indices is an objective approach to assessing the genetic potential of the S4 TS. The selection index formed was 0.53 ear weight + 0.24-grain yield percentage + yield. …”
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Serum α1-AT Levels and <i>SERPINA1</i> Molecular Analysis in Breast Cancer: An Experimental and Computational Study by Guadalupe Ávalos-Navarro, Luis A. Bautista-Herrera, Asbiel Felipe Garibaldi-Ríos, Ramiro Ramírez-Patiño, Marisol Gutiérrez-García, Perla Briseño-Álvarez, Luis Felipe Jave-Suárez, Emmanuel Reyes-Uribe, Martha Patricia Gallegos-Arreola

“…Background/Objectives: Breast cancer (BC) is a heterogeneous disease with multifactorial origins, including environmental, genetic, and immunological factors. Inflammatory cytokines, such as alpha 1 antitrypsin (α1-AT), are increased in BC and affect physiological and pathological conditions. …”
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Claim Amount Forecasting and Pricing of Automobile Insurance Based on the BP Neural Network by Wenguang Yu, Guofeng Guan, Jingchao Li, Qi Wang, Xiaohan Xie, Yu Zhang, Yujuan Huang, Xinliang Yu, Chaoran Cui

“…The main method that has been used in the prediction of the total claim amount in automobile insurance is the generalized linear model, where the BP neural network model could provide a different approach to estimate the total claim loss. This paper uses a genetic algorithm to optimize the structure of the BP neural network at first, and the calculation speed is significantly improved. …”
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Pyelonephritis and Bacteremia Caused by Klebsiella variicola following Renal Transplantation by Cody Lo, Shazia Masud, Gregory D. Deans

“…Klebsiella variicola (K. variicola) is a Gram-negative organism genetically similar to Klebsiella pneumoniae (K. pneumoniae) that can cause a variety of diseases in humans. …”
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Hot deformation physical mechanisms and a unified constitutive model of a solid solution Ti55511 alloy deformed in the two-phase region by Huijie Zhang, Y.C. Lin, Gang Su, Yongfu Xie, Wei Qiu, Ningfu Zeng, Song Zhang, Guicheng Wu

“…Material constants are determined using a genetic algorithm (GA), and the experimental data align well with the predicted data. …”
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Assessment of MGMT and TERT Subtypes and Prognosis of Glioblastoma by Whole Tumor Apparent Diffusion Coefficient Histogram Analysis by Ling Chen, Min Wu, Yao Li, Lifang Tang, Chuyun Tang, Lizhao Huang, Tao Li, Li Zhu

“…We aimed to evaluate whether apparent diffusion coefficient (ADC) histogram analysis can better predict MGMT and TERT molecular characteristics and to determine the prognostic relevance of genetic profile in patients with GBM. Materials and Methods: MRI, clinical, and pathological data of 79 patients with GBM were retrospectively collected. …”
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Association of anti-phospholipid antibodies and hepatitis B virus infection in Najaf Governorate by Ameer Mohammed Kadhim, Hawraa Ameer Mubark, Dhefaf Hameed Al-Mudhafar, Zainab Hayder Abdulmajeed

“…Abstract Background: Antiphospholipid syndrome (APS) is an autoimmune disease with multifactorial risk factors including genetic and environmental factors such as viral infection, and it can be diagnosed by the presence of antiphospholipid antibodies (APLA) in the serum. …”
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Challenges and Novelties in the Treatment of Obesity in Adults. A review by Karolina Kuczapska, Marek Kurowski, Anna Gliwa, Monika Ryglewicz, Dariusz Fabian, Elżbieta Leszczyńska-Knaga, Natalia Jakubczyk, Weronika Rutkowska-Kawalec, Paweł Moczydłowski, Karolina Michalczuk

“…Etiology of this disease includes different factors from genetic, environmental, and lifestyle fields, while effective management of obesity is still being studied.  …”
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De novo assembly of the complete mitochondrial genomes of two Camellia-oil tree species reveals their multibranch conformation and evolutionary relationships by Zhun Xiao, Yiyang Gu, Junqin Zhou, Mengqi Lu, Jinfeng Wang, Kaizheng Lu, Yanling Zeng, Xiaofeng Tan

“…Additionally, these results enrich Camellia genetic resources and expand our knowledge of mitogenome variation.…”
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The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile. by Glen P Carter, Gillian R Douce, Revathi Govind, Pauline M Howarth, Kate E Mackin, Janice Spencer, Anthony M Buckley, Ana Antunes, Despina Kotsanas, Grant A Jenkin, Bruno Dupuy, Julian I Rood, Dena Lyras

“…Various hypotheses have been proposed for the emergence of these strains, and for their persistence and increased virulence, but supportive experimental data are lacking. Here we describe a genetic approach using isogenic strains to identify a factor linked to the development of hypervirulence in C. difficile. …”
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Direct and Indirect Protein Interactions Link FUS Aggregation to Histone Post-Translational Modification Dysregulation and Growth Suppression in an ALS/FTD Yeast Model by Seth A. Bennett, Samantha N. Cobos, Raven M. A. Fisher, Elizaveta Son, Rania Frederic, Rianna Segal, Huda Yousuf, Kaitlyn Chan, David K. Dansu, Mariana P. Torrente

“…Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are incurable neurodegenerative disorders sharing pathological and genetic features, including mutations in the <i>FUS</i> gene. …”
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Characterization of m6A Methylation Modification Patterns in Colorectal Cancer Determines Prognosis and Tumor Microenvironment Infiltration by Qingfang Yue, Yuan Zhang, Fei Wang, Fei Cao, Jun Bai, Xianglong Duan

“…The results indicated that the expression profiles and genetic mutations of 21 genes encoding m6A methylation regulators in CRC were characterized by a high degree of heterogeneity. …”
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A Newborn with Genital Ambiguity, 45,X/46,XY Mosaicism, a Jumping Chromosome Y, and Congenital Adrenal Hyperplasia by Lei Zhang, Linda D. Cooley, Sonal R. Chandratre, Atif Ahmed, Jill D. Jacobson

“…Our report documents the medical and genetic complexity of children such as this one with ambiguous genitalia and discusses the need for a multidisciplinary team approach.…”
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Transcriptome and weighted gene co-expression network analysis of jujube (Ziziphus jujuba Mill.) fruit reveal putative genes involved in proanthocyanin biosynthesis and regulation by Wenqiang Wang, Yunfeng Pu, Hao Wen, Dengyang Lu, Min Yan, Minzhe Liu, Minyu Wu, Hongjin Bai, Lirong Shen, Cuiyun Wu

“…These findings provide valuable knowledge to facilitate its genetic studies and molecular breeding.…”
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